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Title: Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles

Journal Article · · Nature Photonics
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  1. Technische Univ. Berlin (Germany). Inst. fur Optik und Atomare Physik (IOAP); SLAC National Accelerator Lab., Menlo Park, CA (United States). Linac Coherent Light Source (LCLS); SLAC National Accelerator Lab., Menlo Park, CA (United States). Photon Ultrafast Laser Science and Engineering Inst. (PULSE)
  2. Technische Univ. Berlin (Germany). Inst. fur Optik und Atomare Physik (IOAP)
  3. SLAC National Accelerator Lab., Menlo Park, CA (United States). Linac Coherent Light Source (LCLS); SLAC National Accelerator Lab., Menlo Park, CA (United States). Photon Ultrafast Laser Science and Engineering Inst. (PULSE)
  4. Technische Univ. Berlin (Germany). Inst. fur Optik und Atomare Physik (IOAP); SLAC National Accelerator Lab., Menlo Park, CA (United States). Linac Coherent Light Source (LCLS); Argonne National Lab. (ANL), Argonne, IL (United States)
  5. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics
  6. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics; European X-ray Free-Electron Laser (XFEL), Hamburg (Germany)
  7. Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Center for Free-Electron Laser Science
  8. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics, and Science for Life Lab., Division of Scientific Computing, Dept. of Information Technology
  9. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics; Czech Academy of Science, Prague (Czech Republic). ELI Beamlines, Inst. of Physics; Chalmers Univ. of Technology, Gothenburg (Sweden)
  10. Czech Academy of Science, Prague (Czech Republic). ELI Beamlines, Inst. of Physics
  11. SLAC National Accelerator Lab., Menlo Park, CA (United States). Linac Coherent Light Source (LCLS)
  12. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics; KTH Royal Inst. of Technology, Stockholm (Sweden). AlbaNova Univ. Center, Dept. of Applied Physics, and Biomedical and X-ray Physics
  13. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics, and Dept. of Physics and Astronomy
  14. SLAC National Accelerator Lab., Menlo Park, CA (United States). Linac Coherent Light Source (LCLS); Brookhaven National Lab. (BNL), Upton, NY (United States). National Synchrotron Light Source II (NSLS-II)
  15. Research Inst. for Solid State Physics and Optics, Budapest (Hungary)
  16. Uppsala Univ. (Sweden). Dept. of Cell and Molecular Biology, Lab. of Molecular Biophysics; European X-ray Free-Electron Laser (XFEL), Hamburg (Germany); Czech Academy of Science, Prague (Czech Republic). ELI Beamlines, Inst. of Physics
  17. SLAC National Accelerator Lab., Menlo Park, CA (United States). Linac Coherent Light Source (LCLS); SLAC National Accelerator Lab., Menlo Park, CA (United States). Photon Ultrafast Laser Science and Engineering Inst. (PULSE); Argonne National Lab. (ANL), Argonne, IL (United States); Northwestern Univ., Evanston, IL (United States). Dept. of Physics
+ Show Author Affiliations

Ultrafast X-ray imaging on individual fragile specimens such as aerosols, metastable particles, superfluid quantum systems and live biospecimens provides high-resolution information that is inaccessible with conventional imaging techniques. Coherent X-ray diffractive imaging, however, suffers from intrinsic loss of phase, and therefore structure recovery is often complicated and not always uniquely defined. Here in this paper, we introduce the method of in-flight holography, where we use nanoclusters as reference X-ray scatterers to encode relative phase information into diffraction patterns of a virus. The resulting hologram contains an unambiguous three-dimensional map of a virus and two nanoclusters with the highest lateral resolution so far achieved via single shot X-ray holography. Our approach unlocks the benefits of holography for ultrafast X-ray imaging of nanoscale, non-periodic systems and paves the way to direct observation of complex electron dynamics down to the attosecond timescale.

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States); SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States); Brookhaven National Laboratory (BNL), Upton, NY (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences, and Biosciences Division; German Federal Ministry of Education and Research (BMBF); German Research Foundation (DFG); Swedish Research Council (SRC)
Grant/Contract Number:
AC02-06CH11357; AC02-76SF00515; SC0012704
OSTI ID:
1425332
Alternate ID(s):
OSTI ID: 1423121; OSTI ID: 1433977
Report Number(s):
SLAC-PUB-17234; BNL-203512-2018-JAAM; 142149
Journal Information:
Nature Photonics, Vol. 12, Issue 3; ISSN 1749-4885
Publisher:
Nature Publishing GroupCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 40 works
Citation information provided by
Web of Science

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Cited By (9)

Real-time observation of X-ray-induced intramolecular and interatomic electronic decay in CH2I2 journal May 2019
The role of transient resonances for ultra-fast imaging of single sucrose nanoclusters journal January 2020
3D-printable portable open-source platform for low-cost lens-less holographic cellular imaging journal August 2019
Tunable High Spatio-Spectral Purity Undulator Radiation from a Transported Laser Plasma Accelerated Electron Beam journal December 2019
Holographic phase retrieval and reference design journal August 2019
Refinement for single-nanoparticle structure determination from low-quality single-shot coherent diffraction data journal January 2020
Considerations for three-dimensional image reconstruction from experimental data in coherent diffractive imaging text January 2018
3D-printable portable open-source platform for low-cost lens-less holographic cellular imaging preprint January 2019
Ptychographic wavefront characterisation for single-particle imaging at X-ray lasers preprint January 2020

Linked Research (1)

Figures / Tables (5)

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Related Subjects

71 CLASSICAL AND QUANTUM MECHANICS
GENERAL PHYSICS
77 NANOSCIENCE AND NANOTECHNOLOGY
Ultrafast photonics
X-rays
Imaging and sensing
Nanoparticles