Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5′ exonuclease activities

Uson, Maria Loressa; Carl, Ayala; Goldgur, Yehuda; Shuman, Stewart

doi:10.1093/nar/gky238

Title: Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5′ exonuclease activities

Journal Article · Mon Apr 09 00:00:00 EDT 2018 · Nucleic Acids Research

DOI:https://doi.org/10.1093/nar/gky238· OSTI ID:1432392

Uson, Maria Loressa ^[1]; Carl, Ayala ^[1]; Goldgur, Yehuda ^[2]; Shuman, Stewart ^[1]

Molecular Biology Program, Sloan-Kettering Institute, New York, NY 10065, USA
Structural Biology Program, Sloan-Kettering Institute, New York, NY 10065, USA

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Sponsoring Organization:: USDOE

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 1432392

Journal Information:: Nucleic Acids Research, Journal Name: Nucleic Acids Research Vol. 46 Journal Issue: 8; ISSN 0305-1048

Publisher:: Oxford University PressCopyright Statement

Country of Publication:: United Kingdom

Language:: English

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Cited by: 5 works

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