Electrooxidative Tandem Cyclization of Activated Alkynes with Sulfinic Acids To Access Sulfonated Indenones

Journal Article · Thu May 25 00:00:00 EDT 2017 · Organic Letters

DOI:https://doi.org/10.1021/acs.orglett.7b01256· OSTI ID:1427529

Wen, Jiangwei ^[1]; Shi, Wenyan ^[2]; Zhang, Fan ^[2]; Liu, Dong ^[2]; Tang, Shan ^[2]; Wang, Huamin ^[2]; Lin, Xiao-Min ^[3]; Lei, Aiwen  ^[2]

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1. The Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei, China; Center for Nanoscale Materials, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439, United States
2. The Institute for Advanced Studies (IAS), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, Hubei, China
3. Center for Nanoscale Materials, Argonne National Laboratory, 9700 South Cass Avenue, Argonne, Illinois 60439, United States

An,electrooxidative direct arylsulfonlylation of yones sulfintc acids via a radical tandem cyclization strategy has been developed for the construction of sulfonated ilicIenones:under oxidant, free conditions. This method provides a simple and efficient approach to prepare various sulfonylindenones in good to,excellent:Tyidds,, demonstrating the tremendous prospect of utilizing electrocatalysis in oxidative coupling, Notably, this reaction could Be easily scaled up with good, efficiency.

• Research Organization: Argonne National Lab. (ANL), Argonne, IL (United States)
• Sponsoring Organization: National Natural Science Foundation of China (NNSFC); USDOE Office of Science - Office of Basic Energy Sciences - Scientific User Facilities Division
• DOE Contract Number: AC02-06CH11357
• OSTI ID: 1427529
• Journal Information: Organic Letters, Vol. 19, Issue 12; ISSN 1523-7060
• Publisher: American Chemical Society
• Country of Publication: United States
• Language: English