Structural Basis for Functional Tetramerization of Lentiviral Integrase
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July 2009 |
Improving the Accuracy of Macromolecular Structure Refinement at 7 Å Resolution
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June 2012 |
Solving structures of protein complexes by molecular replacement with Phaser
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December 2006 |
Structural Analysis of a Mutant of the HIV-1 Integrase Zinc Finger Domain That Forms a Single Conformation
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April 2006 |
Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein
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December 2001 |
Three new structures of the core domain of HIV-1 integrase: An active site that binds magnesium
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August 1998 |
Modulating Target Site Selection During Human Immunodeficiency Virus DNA Integration In Vitro with an Engineered Tethering Factor
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September 2006 |
Isolation and Characterization of an Oligomerization-Negative Mutant of HIV-1 Integrase
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July 1999 |
Retroviral intasome assembly and inhibition of DNA strand transfer
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January 2010 |
A role for LEDGF/p75 in targeting HIV DNA integration
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November 2005 |
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
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September 1998 |
A Soluble Active Mutant of HIV-1 Integrase: INVOLVEMENT OF BOTH THE CORE AND CARBOXYL-TERMINAL DOMAINS IN MULTIMERIZATION
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March 1996 |
Retroviral DNA integration directed by HIV integration protein in vitro
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September 1990 |
Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding
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July 2000 |
Allosteric integrase inhibitor potency is determined through the inhibition of HIV-1 particle maturation
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April 2013 |
Oligomeric States of the HIV-1 Integrase As Measured by Time-Resolved Fluorescence Anisotropy †
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August 2000 |
Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling
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March 2000 |
LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery
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October 2011 |
XDS
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January 2010 |
Augmentation of Reverse Transcription by Integrase through an Interaction with Host Factor, SIP1/Gemin2 Is Critical for HIV-1 Infection
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November 2009 |
Non-Catalytic Site HIV-1 Integrase Inhibitors Disrupt Core Maturation and Induce a Reverse Transcription Block in Target Cells
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September 2013 |
HIV DNA Integration
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May 2012 |
Regression Shrinkage and Selection Via the Lasso
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January 1996 |
The A128T Resistance Mutation Reveals Aberrant Protein Multimerization as the Primary Mechanism of Action of Allosteric HIV-1 Integrase Inhibitors
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April 2013 |
Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis
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May 2006 |
A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
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January 2009 |
Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA.
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February 1991 |
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
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January 2013 |
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
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July 2007 |
Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1
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January 2014 |
Features and development of Coot
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March 2010 |
Mechanisms associated with the generation of biologically active human immunodeficiency virus type 1 particles from defective proviruses.
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March 1991 |
Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs
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May 2009 |
Structural Properties of HIV Integrase·Lens Epithelium-derived Growth Factor Oligomers
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April 2010 |
Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication
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May 2010 |
Taxol Allosterically Alters the Dynamics of the Tubulin Dimer and Increases the Flexibility of Microtubules
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October 2008 |
HIV-1 Integration in the Human Genome Favors Active Genes and Local Hotspots
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August 2002 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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January 2010 |
The structural biology of HIV-1: mechanistic and therapeutic insights
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March 2012 |
Version 1.2 of the Crystallography and NMR system
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October 2007 |
The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase
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November 2014 |
Role of metal ions in catalysis by HIV integrase analyzed using a quantitative PCR disintegration assay
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November 2006 |
Allosteric Inhibition of Human Immunodeficiency Virus Integrase: LATE BLOCK DURING VIRAL REPLICATION AND ABNORMAL MULTIMERIZATION INVOLVING SPECIFIC PROTEIN DOMAINS
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June 2014 |
The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy
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January 2013 |
Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes
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journal
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July 2001 |
A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase
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May 2014 |
X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293) - an initial glance of the viral DNA binding platform 1 1Edited by I. A. Wilson
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February 2000 |
Phaser crystallographic software
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July 2007 |
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
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January 2013 |
The intrinsic structure of poly(A) RNA determines the specificity of Pan2 and Caf1 deadenylases
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May 2019 |
New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action
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April 2012 |
A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase
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August 2014 |
HIV integrase as a target for antiretroviral therapy
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January 2012 |
HIV-1 Antiretroviral Drug Therapy
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January 2012 |
Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain
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April 2001 |
Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum
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March 2012 |
Deformable elastic network refinement for low-resolution macromolecular crystallography
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August 2014 |
Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization
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June 2012 |
Preclinical Profile of BI 224436, a Novel HIV-1 Non-Catalytic-Site Integrase Inhibitor
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March 2014 |
Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation
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July 2015 |
Structure-based mutagenesis of the catalytic domain of human immunodeficiency virus type 1 integrase.
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January 1997 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
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January 2010 |