P-MartCancer–Interactive Online Software to Enable Analysis of Shotgun Cancer Proteomic Datasets

Journal Article · Tue Oct 31 00:00:00 EDT 2017 · Cancer Research

DOI:https://doi.org/10.1158/0008-5472.CAN-17-0335· OSTI ID:1414547

Webb-Robertson, Bobbie-Jo M.; Bramer, Lisa M.; Jensen, Jeffrey L.; Kobold, Markus A.; Stratton, Kelly G.; White, Amanda M.; Rodland, Karin D.

P-MartCancer is a new interactive web-based software environment that enables biomedical and biological scientists to perform in-depth analyses of global proteomics data without requiring direct interaction with the data or with statistical software. P-MartCancer offers a series of statistical modules associated with quality assessment, peptide and protein statistics, protein quantification and exploratory data analyses driven by the user via customized workflows and interactive visualization. Currently, P-MartCancer offers access to multiple cancer proteomic datasets generated through the Clinical Proteomics Tumor Analysis Consortium (CPTAC) at the peptide, gene and protein levels. P-MartCancer is deployed using Azure technologies (http://pmart.labworks.org/cptac.html), the web-service is alternatively available via Docker Hub (https://hub.docker.com/r/pnnl/pmart-web/) and many statistical functions can be utilized directly from an R package available on GitHub (https://github.com/pmartR).

• Research Organization: Pacific Northwest National Laboratory (PNNL), Richland, WA (US)
• Sponsoring Organization: USDOE
• DOE Contract Number: AC05-76RL01830
• OSTI ID: 1414547
• Report Number(s): PNNL-SA-123730; 453040220
• Journal Information: Cancer Research, Journal Name: Cancer Research Journal Issue: 21 Vol. 77; ISSN 0008-5472
• Publisher: American Association for Cancer Research
• Country of Publication: United States
• Language: English