Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

Journal Article · Fri Aug 01 00:00:00 EDT 2014 · Structure

DOI:https://doi.org/10.1016/j.str.2014.06.009· OSTI ID:1392741

Calabrese, Matthew F.; Rajamohan, Francis; Harris, Melissa S.; Caspers, Nicole L.; Magyar, Rachelle; Withka, Jane M.; Wang, Hong; Borzilleri, Kris A.; Sahasrabudhe, Parag V.; Hoth, Lise R.; Geoghegan, Kieran F.; Han, Seungil; Brown, Janice; Subashi, Timothy A.; Reyes, Allan R.; Frisbie, Richard K.; Ward, Jessica; Miller, Russell A.; Landro, James A.; Londregan, Allyn T. ; Carpino, Philip A.; Cabral, Shawn; Smith, Aaron C.; Conn, Edward L.; Cameron, Kimberly O.; Qiu, Xiayang; Kurumbail, Ravi G.

Not Available

• Sponsoring Organization: USDOE
• Grant/Contract Number: NONE; AC02-06CH11357; AC02-05CH11231
• OSTI ID: 1392741
• Journal Information: Structure, Journal Name: Structure Journal Issue: 8 Vol. 22; ISSN 0969-2126
• Publisher: Elsevier
• Country of Publication: United Kingdom
• Language: English