Structural and Functional Characterization of the Monomeric U-Box Domain from E4B
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journal
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January 2010 |
Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains
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July 2015 |
The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation
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March 2001 |
The DNA Damage Response: Making It Safe to Play with Knives
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journal
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October 2010 |
Solving structures of protein complexes by molecular replacement with Phaser
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December 2006 |
Activation of UbcH5c∼Ub Is the Result of a Shift in Interdomain Motions of the Conjugate Bound to U-Box E3 Ligase E4B
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journal
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April 2013 |
Structure of the BRCT Repeat Domain of MDC1 and Its Specificity for the Free COOH-terminal End of the γ-H2AX Histone Tail
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journal
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July 2005 |
CellProfiler: image analysis software for identifying and quantifying cell phenotypes
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journal
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October 2006 |
Pathways of ubiquitin conjugation.
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journal
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December 1997 |
RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling
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September 2012 |
Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase
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December 2007 |
PRIMUS: a Windows PC-based system for small-angle scattering data analysis
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September 2003 |
RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins
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November 2007 |
Ubiquitin-binding domains
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journal
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October 2006 |
RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly
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November 2007 |
ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling
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journal
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February 2014 |
E2 Conjugating Enzyme Selectivity and Requirements for Function of the E3 Ubiquitin Ligase CHIP
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journal
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April 2011 |
Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine
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journal
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August 2013 |
Abraxas and RAP80 Form a BRCA1 Protein Complex Required for the DNA Damage Response
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journal
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May 2007 |
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
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journal
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August 2007 |
Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments
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August 2013 |
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
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journal
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December 2007 |
BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer
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journal
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August 2012 |
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2–hUbc13
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journal
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August 2001 |
DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities
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journal
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January 2014 |
High-Yield Expression in Escherichia coli and Purification of Mouse Ubiquitin-Activating Enzyme E1
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journal
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October 2011 |
E2 interaction and dimerization in the crystal structure of TRAF6
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journal
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May 2009 |
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
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journal
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July 2009 |
Noncanonical E2 Variant-Independent Function of UBC13 in Promoting Checkpoint Protein Assembly
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journal
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August 2008 |
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
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journal
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December 2005 |
Antisense PMO Found in Dystrophic Dog Model Was Effective in Cells from Exon 7-Deleted DMD Patient
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journal
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August 2010 |
Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80
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journal
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June 2009 |
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source
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journal
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January 2013 |
New insights into ubiquitin E3 ligase mechanism
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journal
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April 2014 |
Chaperoned Ubiquitylation—Crystal Structures of the CHIP U Box E3 Ubiquitin Ligase and a CHIP-Ubc13-Uev1a Complex
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journal
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November 2005 |
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
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journal
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October 2015 |
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin
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journal
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March 2006 |
High-Throughput SAXS for the Characterization of Biomolecules in Solution: A Practical Approach
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book
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October 2013 |
Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering
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journal
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February 2015 |
Ubiquitin: structures, functions, mechanisms
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journal
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November 2004 |
FoXS: a web server for rapid computation and fitting of SAXS profiles
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journal
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May 2010 |
Distinct Roles of Chromatin-Associated Proteins MDC1 and 53BP1 in Mammalian Double-Strand Break Repair
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journal
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December 2007 |
Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin
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journal
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April 2008 |
Mechanism of ubiquitylation by dimeric RING ligase RNF4
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journal
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August 2011 |
A Guide to Simple and Informative Binding Assays
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journal
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December 2010 |
Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis
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journal
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May 2008 |
Molecular Insights into the Function of RING Finger (RNF)-containing Proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent Ubiquitylation
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journal
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May 2012 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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journal
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January 2010 |
The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation
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journal
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January 2006 |
Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software
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journal
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February 2011 |
RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
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journal
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January 2014 |
Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting
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journal
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May 2015 |
The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage
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journal
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February 2009 |
Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases
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journal
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September 2012 |
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
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journal
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March 2011 |
Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law
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journal
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April 2011 |
Structure and flexibility within proteins as identified through small angle X-ray scattering
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journal
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January 2009 |
Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis
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journal
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July 2012 |
The Ubiquitin Code
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journal
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July 2012 |
RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins
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journal
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February 2009 |
Structural Mechanisms Underlying Posttranslational Modification by Ubiquitin-Like Proteins
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journal
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June 2007 |
Phaser crystallographic software
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journal
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July 2007 |
Mre11–Rad50–Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin templateThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
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journal
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August 2007 |