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Title: Array-based detection of genetic alterations associated with disease

Patent ·
OSTI ID:1379191

The present invention relates to DNA sequences from regions of copy number change on chromosome 20. The sequences can be used in hybridization methods for the identification of chromosomal abnormalities associated with various diseases.

Research Organization:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC03-76SF00098
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Patent Number(s):
9,753,035
Application Number:
11/900,648
OSTI ID:
1379191
Resource Relation:
Patent File Date: 2007 Sep 11
Country of Publication:
United States
Language:
English

References (7)

Detection of amplified or deleted chromosomal regions patent December 1995
Genes from the 20Q13 amplicon and their uses patent April 1999
Array-based detection of genetic alterations associated with disease patent April 2001
Array-based detection of genetic alterations associated with disease patent September 2007
Molecular heterogeneity at the breakpoints of smaller 20q deletions journal September 1994
Comparative genomic hybridization of ductal carcinoma in situ of the breast—evidence of multiple genetic pathways journal March 1999
Co-amplification of erbB2, topoisomerase II α and retinoic acid receptor α genes in breast cancer and allelic loss at topoisomerase I on chromosome 20 journal January 1993

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