Molecular and Serological Survey of Selected Viruses in Free-Ranging Wild Ruminants in Iran

Hemmatzadeh, Farhid; Boardman, Wayne; Alinejad, Arezo; Hematzade, Azar; Moghadam, Majid Kharazian; Andrei, Graciela

doi:10.1371/journal.pone.0168756

Title: Molecular and Serological Survey of Selected Viruses in Free-Ranging Wild Ruminants in Iran

Journal Article · Tue Dec 20 00:00:00 EST 2016 · PLoS ONE

DOI:https://doi.org/10.1371/journal.pone.0168756· OSTI ID:1378484

Hemmatzadeh, Farhid ^[1]; Boardman, Wayne ^[2]; Alinejad, Arezo ^[3]; Hematzade, Azar ^[4]; Moghadam, Majid Kharazian ^[5]; Andrei, Graciela ^[6]

Univ. of Adelaide, SA (Australia). School of Animal and Veterinary Sciences
Univ. of Adelaide, SA (Australia). School of Animal and Veterinary Sciences; Univ. of South Australia, Adelaide, SA (Australia). School of Pharmacy and Medical Sciences
Univ. of Tehran, Tehran (Iran). Faculty of Veterinary Medicine
Islamic Azad Univ., Shahrekord (Iran)
Iran Dept. of Environment, Tehran (Iran)
Katholieke Universiteit Leuven Rega Institute for Medical Research, Belgium

A molecular and serological survey of selected viruses in free-ranging wild ruminants was conducted in 13 different districts in Iran. Samples were collected from 64 small wild ruminants belonging to four different species including 25 Mouflon (Ovis orientalis), 22 wild goat (Capra aegagrus), nine Indian gazelle (Gazella bennettii) and eight Goitered gazelle (Gazella subgutturosa) during the national survey for wildlife diseases in Iran. Serum samples were evaluated using serologic antibody tests for Peste de petits ruminants virus (PPRV), Pestiviruses [Border Disease virus (BVD) and Bovine Viral Diarrhoea virus (BVDV)], Bluetongue virus (BTV), Bovine herpesvirus type 1 (BHV-1), and Parainfluenza type 3 (PI3). Sera were also ELISA tested for Pestivirus antigen. Tissue samples including spleen, liver, lung, tonsils, mesenteric and mediastinal lymph nodes and white blood cells (WBCs) were tested using polymerase chain reaction (PCR) for PPRV, Foot and Mouth Disease virus (FMDV), Pestivirus, BTV, Ovine herpesvirus type 2 (OvHV-2) and BHV-1. Serologic tests were positive for antibodies against PPRV (17%), Pestiviruses (2%) and BTV (2%). No antibodies were detected for BHV-1 or PI3, and no Pestivirus antigen was detected. PCR results were positive for PPRV (7.8%), FMDV (11%), BTV (3%), OvHV-2 (31%) and BHV-1 (1.5%). Finally, none of the samples were positive for Pestiviruses.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Univ. of Adelaide, SA (Australia). School of Animal and Veterinary Sciences

Sponsoring Organization:: Iran DoE

Grant/Contract Number:: 01-1384

OSTI ID:: 1378484

Journal Information:: PLoS ONE, Vol. 11, Issue 12; ISSN 1932-6203

Publisher:: Public Library of ScienceCopyright Statement

Country of Publication:: United States

Language:: English

Citation Metrics:

Cited by: 8 works

Citation information provided by
Web of Science

References (64)

The role of wildlife in bluetongue virus maintenance in Europe: Lessons learned after the natural infection in Spain Ruiz-Fons, Francisco; Sánchez-Matamoros, Almudena; Gortázar, Christian Virus Research, Vol. 182 https://doi.org/10.1016/j.virusres.2013.12.031	journal	March 2014
Bluetongue: Laboratory diagnosis Afshar, Ahmad Comparative Immunology, Microbiology and Infectious Diseases, Vol. 17, Issue 3-4 https://doi.org/10.1016/0147-9571(94)90045-0	journal	August 1994
Serological survey of antibodies against BVD virus in camels (Camelus dromedarius) in Iran Raoofi, Afshin; Hemmatzadeh, Farhid; Ghanaei, Amir Mansoor Tropical Animal Health and Production, Vol. 42, Issue 3 https://doi.org/10.1007/s11250-009-9435-3	journal	August 2009
Investigation of the Role of Austrian Ruminant Wildlife in the Epidemiology of Malignant Catarrhal Fever Viruses Benetka, V.; Krametter-Froetscher, R.; Baumgartner, W. Journal of Wildlife Diseases, Vol. 45, Issue 2 https://doi.org/10.7589/0090-3558-45.2.508	journal	April 2009
Occurrence of precipitating antibodies to bluetongue virus in sera of farm animals in Iran Afshar, A.; Kayvanfar, H. Veterinary Record, Vol. 94, Issue 11 https://doi.org/10.1136/vr.94.11.233	journal	March 1974
Clinical and Para-clinical Findings of a Recent Outbreaks of Peste des Petits Ruminants in Iran Abdollahpour, G.; Raoofi, A.; Najafi, J. Journal of Veterinary Medicine Series B, Vol. 53, Issue s1 https://doi.org/10.1111/j.1439-0450.2006.01013.x	journal	December 2006
Emerging Infectious Diseases of Wildlife-- Threats to Biodiversity and Human Health Daszak, P. Science, Vol. 287, Issue 5452 https://doi.org/10.1126/science.287.5452.443	journal	January 2000
Aspects of the persistence of foot-and-mouth disease virus in animals—the carrier problem Alexandersen, Soren; Zhang, Zhidong; Donaldson, Alex I. Microbes and Infection, Vol. 4, Issue 10 https://doi.org/10.1016/s1286-4579(02)01634-9	journal	August 2002
The Pathogenesis and Diagnosis of Foot-and-Mouth Disease Alexandersen, S.; Zhang, Z.; Donaldson, A. I. Journal of Comparative Pathology, Vol. 129, Issue 1 https://doi.org/10.1016/S0021-9975(03)00041-0	journal	July 2003
A review of experimental infections with bluetongue virus in the mammalian host Coetzee, Peter; van Vuuren, Moritz; Venter, Estelle. H. Virus Research, Vol. 182 https://doi.org/10.1016/j.virusres.2013.12.044	journal	March 2014
Viral Metagenomics on Animals as a Tool for the Detection of Zoonoses Prior to Human Infection? Temmam, Sarah; Davoust, Bernard; Berenger, Jean-Michel International Journal of Molecular Sciences, Vol. 15, Issue 6 https://doi.org/10.3390/ijms150610377	journal	June 2014
Bovine viral diarrhea virus infections in heterologous species Passler, Thomas; Walz, Paul H. Animal Health Research Reviews, Vol. 11, Issue 2 https://doi.org/10.1017/S1466252309990065	journal	November 2009
Cytogenetic analyses of wild sheep populations in northern Iran Nadler, C. F.; Lay, D. M.; Hassinger, J. D. Cytogenetic and Genome Research, Vol. 10, Issue 2 https://doi.org/10.1159/000130135	journal	January 1971
Malignant catarrhal fever: A review Russell, George C.; Stewart, James P.; Haig, David M. The Veterinary Journal, Vol. 179, Issue 3 https://doi.org/10.1016/j.tvjl.2007.11.007	journal	March 2009
Isolation of bluetongue virus serotype 1 from aborted goat fetuses Chauhan, H. C.; Biswas, S. K.; Chand, K. Revue Scientifique et Technique de l'OIE, Vol. 33, Issue 3 https://doi.org/10.20506/rst.33.3.2319	journal	December 2014
Epidemiological investigation of bluetongue virus antibodies in sheep in Iran Khezri, Mohammad; Azimi, Seyed Veterinary World https://doi.org/10.5455/vetworld.2013.122-125	journal	January 2013
Grazers on the plains: challenges and prospects for large herbivores in Central Asia Mallon, David P.; Zhigang, Jiang Journal of Applied Ecology, Vol. 46, Issue 3 https://doi.org/10.1111/j.1365-2664.2009.01654.x	journal	June 2009
Molecular epidemiology of foot-and-mouth disease virus Knowles, N. J.; Samuel, A. R. Virus Research, Vol. 91, Issue 1 https://doi.org/10.1016/s0168-1702(02)00260-5	journal	January 2003
Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control Banyard, A. C.; Parida, S.; Batten, C. Journal of General Virology, Vol. 91, Issue 12 https://doi.org/10.1099/vir.0.025841-0	journal	September 2010
Prediction of province-level outbreaks of foot-and-mouth disease in Iran using a zero-inflated negative binomial model Jafarzadeh, S. Reza; Norris, Michelle; Thurmond, Mark C. Preventive Veterinary Medicine, Vol. 115, Issue 3-4 https://doi.org/10.1016/j.prevetmed.2014.03.018	journal	August 2014
Proof of principle: Non-invasive sampling for early detection of foot-and-mouth disease virus infection in wild boar using a rope-in-a-bait sampling technique Mouchantat, Susan; Haas, Bernd; Böhle, Wolfgang Veterinary Microbiology, Vol. 172, Issue 1-2 https://doi.org/10.1016/j.vetmic.2014.05.021	journal	August 2014
Fecundity of Wild Sheep (Ovis orientalis) in Iran Valdez, R. Journal of Mammalogy, Vol. 57, Issue 4 https://doi.org/10.2307/1379451	journal	December 1976
Bluetongue Virus Serotype 1 Outbreak in the Basque Country (Northern Spain) 2007–2008. Data Support a Primary Vector Windborne Transport García-Lastra, Rodrigo; Leginagoikoa, Iratxe; Plazaola, Jose M. PLoS ONE, Vol. 7, Issue 3 https://doi.org/10.1371/journal.pone.0034421	journal	March 2012
Active and Latent Ovine Herpesvirus-2 (OvHV-2) Infection in a Herd of Captive White-tailed Deer (Odocoileus virginianus) Palmer, M. V.; Thacker, T. C.; Madison, R. J. Journal of Comparative Pathology, Vol. 149, Issue 2-3 https://doi.org/10.1016/j.jcpa.2013.01.005	journal	August 2013
Immune Complex-based Vaccine for Pig Protection against Parvovirus Roic, B.; Cajavec, S.; Ergotic, N. Journal of Veterinary Medicine Series B, Vol. 53, Issue 1 https://doi.org/10.1111/j.1439-0450.2006.00907.x	journal	February 2006
Serosurveillance of foot-and-mouth disease virus in selected livestock-wildlife interface areas of Tanzania Mkama, Mathias; Kasanga, Christopher J.; Sallu, Raphael Onderstepoort J Vet Res, Vol. 81, Issue 2 https://doi.org/10.4102/ojvr.v81i2.718	journal	April 2014
Ovine herpesvirus 2 infection in American bison: virus and host dynamics in the development of sheep-associated malignant catarrhal fever Cunha, Cristina W.; Gailbreath, Katherine L.; O’Toole, Donal Veterinary Microbiology, Vol. 159, Issue 3-4 https://doi.org/10.1016/j.vetmic.2012.04.021	journal	October 2012
Detection of Bluetongue Virus Serogroup by Polymerase Chain Reaction Akita, Geoffrey Y.; Chinsangaram, Jarasvech; Osburn, Bennie I. Journal of Veterinary Diagnostic Investigation, Vol. 4, Issue 4 https://doi.org/10.1177/104063879200400405	journal	October 1992
Differentiation of types 1a, 1b and 2 bovine viral diarrhoea virus (BVDV) by PCR Ridpath, Julia F.; Bolin, Steven R. Molecular and Cellular Probes, Vol. 12, Issue 2 https://doi.org/10.1006/mcpr.1998.0158	journal	April 1998
High seroprevalence of bluetongue virus antibodies in goats in southeast Iran Mozaffari, Ali Asghar; Khalili, Mohammad; Sabahi, Sina Asian Pacific Journal of Tropical Biomedicine, Vol. 4 https://doi.org/10.12980/APJTB.4.2014B599	journal	May 2014
Evaluation of polymerase chain reaction for the detection and characterisation of rinderpest and peste des petits ruminants viruses for epidemiological studies Forsyth, M. A.; Barrett, T. Virus Research, Vol. 39, Issue 2-3 https://doi.org/10.1016/0168-1702(95)00076-3	journal	December 1995
A preliminary report on the isolation of bovine malignant catarrhal fever virus in Iran Ramyar, H.; Hessami, M. Veterinary Record, Vol. 91, Issue 25 https://doi.org/10.1136/vr.91.25.630	journal	December 1972
Infectious Diseases and Extinction Risk in Wild Mammals Pedersen, Amy B.; Jones, Kate E.; Nunn, Charles L. Conservation Biology, Vol. 21, Issue 5 https://doi.org/10.1111/j.1523-1739.2007.00776.x	journal	October 2007
Host–pathogen time series data in wildlife support a transmission function between density and frequency dependence Smith, Matthew J.; Telfer, Sandra; Kallio, Eva R. Proceedings of the National Academy of Sciences, Vol. 106, Issue 19 https://doi.org/10.1073/pnas.0809145106	journal	May 2009
A Review of Knowledge Gaps and Tools for Orbivirus Research Drolet, Barbara S.; van Rijn, Piet; Howerth, Elizabeth W. Vector-Borne and Zoonotic Diseases, Vol. 15, Issue 6 https://doi.org/10.1089/vbz.2014.1701	journal	June 2015
The detection of antibodies against peste des petits ruminants virus in cattle, sheep and goats and the possible implications to rinderpest control programmes Anderson, J.; Mckay, J. A. Epidemiology and Infection, Vol. 112, Issue 1 https://doi.org/10.1017/S0950268800057599	journal	February 1994
Bovine viral diarrhea virus in free-ranging wild ruminants in Switzerland: low prevalence of infection despite regular interactions with domestic livestock Casaubon, Julien; Vogt, Hans-Rudolf; Stalder, Hanspeter BMC Veterinary Research, Vol. 8, Issue 1 https://doi.org/10.1186/1746-6148-8-204	journal	October 2012
Role of Wild Small Ruminants in the Epidemiology of Peste Des Petits Ruminants Munir, M. Transboundary and Emerging Diseases, Vol. 61, Issue 5 https://doi.org/10.1111/tbed.12052	journal	January 2013
Peste Des Petits Ruminants Virus Infection of Small Ruminants: A Comprehensive Review Kumar, Naveen; Maherchandani, Sunil; Kashyap, Sudhir Viruses, Vol. 6, Issue 6 https://doi.org/10.3390/v6062287	journal	June 2014
Comparative analysis of equine lymphocyte subsets in whole blood and gradient-purified samples Akens, Margarete K.; Holznagel, E.; Franchini, M. Veterinary Immunology and Immunopathology, Vol. 58, Issue 3-4 https://doi.org/10.1016/S0165-2427(97)00044-5	journal	September 1997
Serosurveillance for Foot-And-Mouth Disease in Mongolian Gazelles (Procapra Gutturosa) and Livestock on the Eastern Steppe of Mongolia Bolortsetseg, Sanjaa; Enkhtuvshin, Shiilegdamba; Nyamsuren, D. Journal of Wildlife Diseases, Vol. 48, Issue 1 https://doi.org/10.7589/0090-3558-48.1.33	journal	January 2012
Malignant Catarrhal Fever: Inching Toward Understanding Li, Hong; Cunha, Cristina W.; Taus, Naomi S. Annual Review of Animal Biosciences, Vol. 2, Issue 1 https://doi.org/10.1146/annurev-animal-022513-114156	journal	February 2014
Surveillance of foot-and-mouth disease (FMD) in susceptible wildlife and domestic ungulates in Southeast of Bulgaria following a FMD case in wild boar Alexandrov, Tsviatko; Stefanov, Dimitar; Kamenov, Pencho Veterinary Microbiology, Vol. 166, Issue 1-2 https://doi.org/10.1016/j.vetmic.2013.05.016	journal	September 2013
The role of wildlife in transboundary animal diseases Siembieda, J. L.; Kock, R. A.; McCracken, T. A. Animal Health Research Reviews, Vol. 12, Issue 1 https://doi.org/10.1017/S1466252311000041	journal	May 2011
PATHOGENS IN WATER DEER (HYDROPOTES INERMIS) IN SOUTH KOREA, 2010–12 Kim, Seol-Hee; Choi, Heelack; Yoon, Junheon Journal of Wildlife Diseases, Vol. 50, Issue 3 https://doi.org/10.7589/2013-06-137	journal	July 2014
Rapid and sensitive polymerase chain reaction based detection and typing of foot-and-mouth disease virus in clinical samples and cell culture isolates, combined with a simultaneous differentiation with other genomically and/or symptomatically related viruses Vangrysperre, W.; De Clercq, K. Archives of Virology, Vol. 141, Issue 2 https://doi.org/10.1007/BF01718403	journal	February 1996
Detection of the bovine herpesvirus-1 (BHV-1) genome by PCR Vilc̆ek, Štefan Journal of Virological Methods, Vol. 41, Issue 2 https://doi.org/10.1016/0166-0934(93)90132-B	journal	February 1993
Wildlife as Source of Zoonotic Infections Kruse, Hilde; Kirkemo, Anne-Mette; Handeland, Kjell Emerging Infectious Diseases, Vol. 10, Issue 12 https://doi.org/10.3201/eid1012.040707	journal	December 2004
Bovine herpesvirus 1 infection and infectious bovine rhinotracheitis Muylkens, Benoît; Thiry, Julien; Kirten, Philippe Veterinary Research, Vol. 38, Issue 2 https://doi.org/10.1051/vetres:2006059	journal	March 2007
Serological survey on bovine parainfluenza type 3 in Shahrekord district (Iran) Kojouri, Gholam Ali; Hemmatzadeh, Farhid; Taghadosi, Camellia Comparative Clinical Pathology, Vol. 20, Issue 3 https://doi.org/10.1007/s00580-010-0958-9	journal	March 2010
Pcr Detection of Bovine Herpesviruses from Nonbovine Ruminants in Hungary Kálmán, Dóra; Egyed, László Journal of Wildlife Diseases, Vol. 41, Issue 3 https://doi.org/10.7589/0090-3558-41.3.482	journal	July 2005
Pestiviruses in wild animals Vilček, Š.; Nettleton, P. F. Veterinary Microbiology, Vol. 116, Issue 1-3 https://doi.org/10.1016/j.vetmic.2006.06.003	journal	August 2006
Bovine Parainfluenza-3 Virus Ellis, John A. Veterinary Clinics of North America: Food Animal Practice, Vol. 26, Issue 3 https://doi.org/10.1016/j.cvfa.2010.08.002	journal	November 2010
Potential role of ticks as vectors of bluetongue virus Bouwknegt, Chantal; van Rijn, Piet A.; Schipper, Jacqueline J. M. Experimental and Applied Acarology, Vol. 52, Issue 2 https://doi.org/10.1007/s10493-010-9359-7	journal	April 2010
Fatalities in Wild Goats in Kurdistan Associated with Peste Des Petits Ruminants Virus Hoffmann, B.; Wiesner, H.; Maltzan, J. Transboundary and Emerging Diseases, Vol. 59, Issue 2 https://doi.org/10.1111/j.1865-1682.2011.01270.x	journal	November 2011
A Review on Peste des Petits Ruminants (PPR) with Special Reference to PPR in Iran Bazarghani, T. T.; Charkhkar, S.; Doroudi, J. Journal of Veterinary Medicine Series B, Vol. 53, Issue s1 https://doi.org/10.1111/j.1439-0450.2006.01014.x	journal	December 2006
A predictive diagnostic model for wild sheep (Ovis orientalis) habitat suitability in Iran Bashari, Hossein; Hemami, Mahmoud-Reza Journal for Nature Conservation, Vol. 21, Issue 5 https://doi.org/10.1016/j.jnc.2013.03.005	journal	October 2013
Gastro-intestinal nematodes of gazelle, Gazella subgutturosa, in Iran Eslami, A.; Rahbari, S.; Nikbin, S. Veterinary Parasitology, Vol. 7, Issue 1 https://doi.org/10.1016/0304-4017(80)90012-6	journal	June 1980
Rinderpest: the veterinary perspective on eradication Roeder, Peter; Mariner, Jeffrey; Kock, Richard Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 368, Issue 1623 https://doi.org/10.1098/rstb.2012.0139	journal	August 2013
Foot and Mouth Disease: a look from the wild side Weaver, Genevieve V.; Domenech, Joseph; Thiermann, Alex R. Journal of Wildlife Diseases, Vol. 49, Issue 4 https://doi.org/10.7589/2012-11-276	journal	October 2013
How stress alters immune responses during respiratory infection Griebel, Philip; Hill, Kevin; Stookey, Joseph Animal Health Research Reviews, Vol. 15, Issue 2 https://doi.org/10.1017/S1466252314000280	journal	December 2014
Ecology and Epidemiology of Zoonotic Pathogens Weinberg, Arnold N. Infectious Disease Clinics of North America, Vol. 5, Issue 1 https://doi.org/10.1016/S0891-5520(20)30384-6	journal	March 1991
Effects of Bovine Herpesvirus Type 1 Infection in Calves with Maternal Antibodies on Immune Response and Virus Latency Lemaire, Mylène; Weynants, Vincent; Godfroid, Jacques Journal of Clinical Microbiology, Vol. 38, Issue 5 https://doi.org/10.1128/JCM.38.5.1885-1894.2000	journal	May 2000
The Merck Veterinary Manual Online (8th edition) Scarth, Linda Loos Reference Reviews, Vol. 20, Issue 2, p. 40-40 https://doi.org/10.1108/09504120610647492	journal	February 2006

Cited By (2)

Global Distribution and Genetic Heterogeneity of Border Disease Virus Righi, Cecilia; Petrini, Stefano; Pierini, Ilaria Viruses, Vol. 13, Issue 6 https://doi.org/10.3390/v13060950	journal	May 2021
Seroprevalence of Foot and Mouth Disease Virus Infection in Some Wildlife and Cattle in Bauchi State, Nigeria Atuman, Y. J.; Kudi, C. A.; Abdu, P. A. Veterinary Medicine International, Vol. 2020 https://doi.org/10.1155/2020/3642793	journal	March 2020

Similar Records

Development and Characterization of A Multiplexed RT-PCR Species Specific Assay for Bovine and one for Porcine Foot-and-Mouth Disease Virus Rule-Out

Technical Report · Mon Aug 06 00:00:00 EDT 2007 · OSTI ID:1378484

Smith, S M; Danganan, L; Tammero, L; +4 more

Development and Characterization of a Multiplexed RT-PCR Species Specific Assay for Bovine and one for Porcine Foot-and-Mouth Disease Virus Rule-Out Supplemental Materials

Technical Report · Mon Aug 06 00:00:00 EDT 2007 · OSTI ID:1378484

Smith, S; Danganan, L; Tammero, L; +3 more

Foot & Mouth Disease & Ulcerative/Vesicular Rule-outs: Challenges Encountered in Recent Outbreaks

Conference · Mon Jan 28 00:00:00 EST 2008 · OSTI ID:1378484

Hullinger, P

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
60 APPLIED LIFE SCIENCES

Title: Molecular and Serological Survey of Selected Viruses in Free-Ranging Wild Ruminants in Iran

Citation Formats

References (64)

Cited By (2)

Similar Records

Related Subjects