skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Polycomb repressive complex 2 in an autoinhibited state

Authors:
; ;
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
UNIVERSITYOTHER
OSTI Identifier:
1376260
Resource Type:
Journal Article
Journal Name:
Journal of Biological Chemistry
Additional Journal Information:
Journal Volume: 292; Journal Issue: 32; Journal ID: ISSN 0021-9258
Publisher:
American Society for Biochemistry and Molecular Biology
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Bratkowski, Matthew, Yang, Xin, and Liu, Xin. Polycomb repressive complex 2 in an autoinhibited state. United States: N. p., 2017. Web. doi:10.1074/jbc.M117.787572.
Bratkowski, Matthew, Yang, Xin, & Liu, Xin. Polycomb repressive complex 2 in an autoinhibited state. United States. doi:10.1074/jbc.M117.787572.
Bratkowski, Matthew, Yang, Xin, and Liu, Xin. Mon . "Polycomb repressive complex 2 in an autoinhibited state". United States. doi:10.1074/jbc.M117.787572.
@article{osti_1376260,
title = {Polycomb repressive complex 2 in an autoinhibited state},
author = {Bratkowski, Matthew and Yang, Xin and Liu, Xin},
abstractNote = {},
doi = {10.1074/jbc.M117.787572},
journal = {Journal of Biological Chemistry},
issn = {0021-9258},
number = 32,
volume = 292,
place = {United States},
year = {2017},
month = {6}
}

Works referenced in this record:

Conservation and Functional Importance of Carbon–Oxygen Hydrogen Bonding in AdoMet-Dependent Methyltransferases
journal, October 2013

  • Horowitz, Scott; Dirk, Lynnette M. A.; Yesselman, Joseph D.
  • Journal of the American Chemical Society, Vol. 135, Issue 41
  • DOI: 10.1021/ja407140k

A model for transmission of the H3K27me3 epigenetic mark
journal, October 2008

  • Hansen, Klaus H.; Bracken, Adrian P.; Pasini, Diego
  • Nature Cell Biology, Vol. 10, Issue 11
  • DOI: 10.1038/ncb1787

Polycomb Group proteins: an evolutionary perspective
journal, October 2007


A687V EZH2 is a gain-of-function mutation found in lymphoma patients
journal, July 2012


Refinement of Macromolecular Structures by the Maximum-Likelihood Method
journal, May 1997

  • Murshudov, G. N.; Vagin, A. A.; Dodson, E. J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 53, Issue 3
  • DOI: 10.1107/S0907444996012255

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance
journal, April 2016

  • Brooun, Alexei; Gajiwala, Ketan S.; Deng, Ya-Li
  • Nature Communications, Vol. 7, Issue 1
  • DOI: 10.1038/ncomms11384

Overview of the CCP 4 suite and current developments
journal, March 2011

  • Winn, Martyn D.; Ballard, Charles C.; Cowtan, Kevin D.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444910045749

Regional control of histone H3 lysine 27 methylation in Neurospora
journal, March 2013

  • Jamieson, K.; Rountree, M. R.; Lewis, Z. A.
  • Proceedings of the National Academy of Sciences, Vol. 110, Issue 15
  • DOI: 10.1073/pnas.1303750110

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
journal, February 2012

  • McCabe, M. T.; Graves, A. P.; Ganji, G.
  • Proceedings of the National Academy of Sciences, Vol. 109, Issue 8
  • DOI: 10.1073/pnas.1116418109

The Fusarium graminearum Histone H3 K27 Methyltransferase KMT6 Regulates Development and Expression of Secondary Metabolite Gene Clusters
journal, October 2013


Product Binding Enforces the Genomic Specificity of a Yeast Polycomb Repressive Complex
journal, January 2015


Nascent RNA interaction keeps PRC2 activity poised and in check
journal, August 2014

  • Kaneko, Syuzo; Son, Jinsook; Bonasio, Roberto
  • Genes & Development, Vol. 28, Issue 18
  • DOI: 10.1101/gad.247940.114

Jarid2 and PRC2, partners in regulating gene expression
journal, February 2010


Asymmetrically Modified Nucleosomes
journal, September 2012


PHENIX: a comprehensive Python-based system for macromolecular structure solution
journal, January 2010

  • Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221
  • DOI: 10.1107/S0907444909052925

Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks
journal, May 2011


NMRPipe: A multidimensional spectral processing system based on UNIX pipes
journal, November 1995

  • Delaglio, Frank; Grzesiek, Stephan; Vuister, GeertenW.
  • Journal of Biomolecular NMR, Vol. 6, Issue 3
  • DOI: 10.1007/BF00197809

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2
journal, April 2016

  • Justin, Neil; Zhang, Ying; Tarricone, Cataldo
  • Nature Communications, Vol. 7, Issue 1
  • DOI: 10.1038/ncomms11316

Role of the polycomb protein EED in the propagation of repressive histone marks
journal, September 2009

  • Margueron, Raphael; Justin, Neil; Ohno, Katsuhito
  • Nature, Vol. 461, Issue 7265
  • DOI: 10.1038/nature08398

Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

Regulatory Interactions between RNA and Polycomb Repressive Complex 2
journal, July 2014


Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2
journal, October 2015