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Title: An RNA Aptamer Capable of Forming a Hydrogel by Self-Assembly

Authors:
 [1];  [2];  [1];  [2]; ORCiD logo [1]
  1. Chemistry Department, University at Albany, State University of New York, Albany, New York 12222, United States
  2. Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, United States
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
National Institutes of Health (NIH)
OSTI Identifier:
1374625
Resource Type:
Journal Article
Resource Relation:
Journal Name: Biomacromolecules; Journal Volume: 18; Journal Issue: 7
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Huang, Zhen, Kangovi, Gagan N., Wen, Wei, Lee, Sangwoo, and Niu, Li. An RNA Aptamer Capable of Forming a Hydrogel by Self-Assembly. United States: N. p., 2017. Web. doi:10.1021/acs.biomac.7b00314.
Huang, Zhen, Kangovi, Gagan N., Wen, Wei, Lee, Sangwoo, & Niu, Li. An RNA Aptamer Capable of Forming a Hydrogel by Self-Assembly. United States. doi:10.1021/acs.biomac.7b00314.
Huang, Zhen, Kangovi, Gagan N., Wen, Wei, Lee, Sangwoo, and Niu, Li. Thu . "An RNA Aptamer Capable of Forming a Hydrogel by Self-Assembly". United States. doi:10.1021/acs.biomac.7b00314.
@article{osti_1374625,
title = {An RNA Aptamer Capable of Forming a Hydrogel by Self-Assembly},
author = {Huang, Zhen and Kangovi, Gagan N. and Wen, Wei and Lee, Sangwoo and Niu, Li},
abstractNote = {},
doi = {10.1021/acs.biomac.7b00314},
journal = {Biomacromolecules},
number = 7,
volume = 18,
place = {United States},
year = {Thu Jun 15 00:00:00 EDT 2017},
month = {Thu Jun 15 00:00:00 EDT 2017}
}
  • No abstract prepared.
  • Highlights: • A new composite hydrogel consisted of Fe{sub 2}O{sub 3} nanotubes and graphene has been prepared via hydrothermal method. • In this composite hydrogel, RGO sheets self-assemble into an interconnected macroporous framework and Fe{sub 2}O{sub 3} nanotubes encapsulate into RGO layers. • The resulting composite hydrogel exhibits high specific capacity (850 mAh/g at 200 mA/g), good rate capability and cycling stability. - Abstract: A novel three-dimensional (3D) Fe{sub 2}O{sub 3}/reduced graphene oxide (RGO) hydrogel (FGH) is prepared by a facile hydrothermal strategy. In this composite hydrogel, RGO sheets self-assemble into an interconnected macroporous framework and Fe{sub 2}O{sub 3} nanotubesmore » encapsulate into RGO layers. The FGH delivers high rate capacities of 850, 780, 550, and 400 mAh/g at current densities of 200, 400, 600, and 800 mA/g, respectively. The specific capacity can still maintain at ∼600 mAh/g after 70 cycles, which greatly outperforms that of pure Fe{sub 2}O{sub 3} nanotubes (∼60 mAh/g after 70 cycles). The improved electrochemical performance is ascribed to the unique macroscopic structure which is beneficial for enlarging the active surface area, shortening the electron/ion pathway, accommodating the volume change of Fe{sub 2}O{sub 3} nanotubes, and preventing the aggregation of both Fe{sub 2}O{sub 3} nanoparticles and RGO sheets.« less
  • The initial stage in the self-assembly of tobacco mosaic virus (TMV) RNA and coat protein into virions involves insertion of a loop of TMV RNA between layers of a double-layered disk of TMV protein (containing 17 coat protein subunits per layer) via the central channel of the disk, followed by conversion of the disk-RNA complex into a two-turn protohelix and addition of more protein (elongation). This mechanism leads to assembling particles in which one of the uncoated RNA tails, that containing the 5'-terminus, runs back along the central channel of the growing rod.
  • No abstract prepared.