skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Biopolymers and supramolecular polymers as biomaterials for biomedical applications

Journal Article · · MRS Bulletin
DOI:https://doi.org/10.1557/mrs.2015.270· OSTI ID:1371112

Abstract

Research Organization:
Energy Frontier Research Centers (EFRC) (United States). Center for Bio-Inspired Energy Science (CBES)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES); National Science Foundation (NSF); National Institutes of Health (NIH)
DOE Contract Number:
SC0000989
OSTI ID:
1371112
Journal Information:
MRS Bulletin, Vol. 40, Issue 12; Related Information: CBES partners with Northwestern University (lead); Harvard University; New York University; Pennsylvania State University; University of Michigan; University of Pittsburgh; ISSN 0883-7694
Publisher:
Materials Research Society
Country of Publication:
United States
Language:
English

References (147)

Mapping the Ligand-binding Sites and Disease-associated Mutations on the Most Abundant Protein in the Human, Type I Collagen journal November 2001
New perspectives in cell adhesion: RGD and integrins journal October 1987
Physical properties of hierarchically ordered self-assembled planar and spherical membranes journal January 2010
A bioengineered peripheral nerve construct using aligned peptide amphiphile nanofibers journal October 2014
Silk structure studied with nuclear magnetic resonance journal February 2013
Reversible Polymers Formed from Self-Complementary Monomers Using Quadruple Hydrogen Bonding journal November 1997
The role of ECM proteins and protein fragments in guiding cell behavior in regenerative medicine journal June 2011
Casting Metal Nanowires Within Discrete Self-Assembled Peptide Nanotubes journal April 2003
Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair journal August 2011
Dynamic reassembly of peptide RADA16 nanofiber scaffold journal June 2005
Self-assembling organic nanotubes based on a cyclic peptide architecture journal December 1993
Self-Assembly and Mineralization of Peptide-Amphiphile Nanofibers journal November 2001
A Healable Supramolecular Polymer Blend Based on Aromatic π−π Stacking and Hydrogen-Bonding Interactions journal September 2010
Design of nanostructures based on aromatic peptide amphiphiles journal January 2014
Polymeric materials based on silk proteins journal September 2008
Fibronectin fibrillogenesis, a cell-mediated matrix assembly process journal September 2005
Cell death versus cell survival instructed by supramolecular cohesion of nanostructures journal February 2014
Silk fibroin matrices for the controlled release of nerve growth factor (NGF) journal October 2007
Binding of soluble form of fibroblast surface protein, fibronectin, to collagen journal July 1977
Nano neuro knitting: Peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision journal March 2006
Host–Guest Driven Self-Assembly of Linear and Star Supramolecular Polymers journal June 2008
Modular, Well-Behaved Reversible Polymers from DNA-Based Monomers journal November 2002
Silk fibroin as a vehicle for drug delivery applications journal March 2011
Supramolecular design of self-assembling nanofibers for cartilage regeneration journal February 2010
Growth factor delivery-based tissue engineering: general approaches and a review of recent developments journal June 2010
Sonic Hedgehog Regulates Brain‐Derived Neurotrophic Factor in Normal and Regenerating Cavernous Nerves journal March 2013
Silk-based biomaterials journal February 2003
Hierarchical Structure and Nanomechanics of Collagen Microfibrils from the Atomistic Scale Up journal February 2011
Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes journal March 1997
Assembly of Human Umbilical Vein Endothelial Cells on Compliant Hydrogels journal March 2010
The extracellular matrix at a glance journal December 2010
The ins and outs of fibronectin matrix assembly journal August 2003
Recombinant Fibronectin Matrix Mimetics Specify Integrin Adhesion and Extracellular Matrix Assembly journal February 2013
Cartilage tissue engineering and bioreactor systems for the cultivation and stimulation of chondrocytes journal February 2007
Self-Assembling Peptide Nanotubes journal January 1996
Thermoreversible Supramolecular Polymer Gels via Metal–Ligand Coordination in an Ionic Liquid journal October 2013
Taking Cell-Matrix Adhesions to the Third Dimension journal November 2001
Physical influences of the extracellular environment on cell migration journal October 2014
Effects of RGDS sequence genetically interfused in the silk fibroin light chain protein on chondrocyte adhesion and cartilage synthesis journal October 2010
Fibronectin fibrillogenesis: a paradigm for extracellular matrix assembly journal October 1999
Role of collagenous matrices in the adhesion and growth of cells journal March 1981
Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide journal September 2005
Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials journal April 2002
Modulation of Cell Proliferation and Differentiation through Substrate-dependent Changes in Fibronectin Conformation journal March 1999
Collagen fibril formation journal May 1996
Acute Excisional Wounds Treated with a Tissue-Engineered Skin (Apligraf) journal January 1999
Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response journal October 1989
A Supramolecular Multi-Block Copolymer with a High Propensity for Alternation journal November 2006
Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair journal July 2002
Development of bioactive peptide amphiphiles for therapeutic cell delivery journal January 2010
Photodynamic Control of Bioactivity in a Nanofiber Matrix journal November 2012
Fibronectin Growth Factor-Binding Domains Are Required for Fibroblast Survival journal January 2011
RGD modified polymers: biomaterials for stimulated cell adhesion and beyond journal November 2003
Nanoconfinement controls stiffness, strength and mechanical toughness of β-sheet crystals in silk journal March 2010
RGD-Functionalized Bioengineered Spider Dragline Silk Biomaterial journal November 2006
Electron microscopic study of supramolecular liquid crystalline polymers formed by molecular-recognition-directed self-assembly from complementary chiral components. journal January 1993
Materials fabrication from Bombyx mori silk fibroin journal September 2011
β1-Integrin and Integrin Linked Kinase Regulate Astrocytic Differentiation of Neural Stem Cells journal August 2014
Silklike materials constructed from sequences of Bombyx mori silk fibroin, fibronectin, and elastin journal July 2007
Regenerative medicine and human models of human disease journal May 2008
Designer functionalized self-assembling peptide nanofiber scaffolds for growth, migration, and tubulogenesis of human umbilical vein endothelial cells journal January 2008
Spontaneous and X-ray-Triggered Crystallization at Long Range in Self-Assembling Filament Networks journal December 2009
A self-assembly pathway to aligned monodomain gels journal June 2010
Unravelling the extracellular matrix journal November 1999
Isolation of a collagen-dependent cell attachment factor journal July 1974
Molecular designer self-assembling peptides journal January 2006
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction journal May 2006
Self-assembly of biomolecular soft matter journal January 2013
A Self-Assembled Delivery Platform with Post-production Tunable Release Rate journal July 2012
Current progress and limitations of spider silk for biomedical applications journal September 2011
Guidance of regrowing sensory axons after cutaneous nerve lesions in the cat journal September 1979
Linkage of functional and structural heterogeneity in proteins: dynamic hole burning in carboxymyoglobin journal October 1987
Self-Assembly of Dendron Rodcoil Molecules into Nanoribbons journal April 2001
Helicoidal multi-lamellar features of RGD-functionalized silk biomaterials for corneal tissue engineering journal December 2010
Nanomechanics of collagen fibrils under varying cross-link densities: Atomistic and continuum studies journal January 2008
Self-Assembly of Large and Small Molecules into Hierarchically Ordered Sacs and Membranes journal March 2008
Tuning Supramolecular Rigidity of Peptide Fibers through Molecular Structure journal May 2010
Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers journal February 2004
Biofunctional Silk/Neuron Interfaces journal February 2012
Novel Vascular Endothelial Growth Factor Binding Domains of Fibronectin Enhance Vascular Endothelial Growth Factor Biological Activity journal July 2002
Collagen scaffolds for tissue engineering journal January 2008
Biological Designer Self-Assembling Peptide Nanofiber Scaffolds Significantly Enhance Osteoblast Proliferation, Differentiation and 3-D Migration journal February 2007
Fibronectin forms the most extensible biological fibers displaying switchable force-exposed cryptic binding sites journal October 2009
Direct conversion of an oligopeptide from a  -sheet to an  -helix: A model for amyloid formation journal January 1997
Fibronectin Polymerization Regulates the Composition and Stability of Extracellular Matrix Fibrils and Cell-Matrix Adhesions journal October 2002
Collagen family of proteins journal October 1991
Hierarchical structures made of proteins. The complex architecture of spider webs and their constituent silk proteins journal January 2010
Construction of Supramolecular Polymers with Alternating α-, β-Cyclodextrin Units Using Conformational Change Induced by Competitive Guests journal September 2004
Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule journal May 1984
Decoding the secrets of spider silk journal March 2011
Recombinant Production of Spider Silk Proteins book January 2013
Functional Supramolecular Polymers journal February 2012
Supramolecular assembly of multifunctional maspin-mimetic nanostructures as a potent peptide-based angiogenesis inhibitor journal January 2015
In vivo studies on angiogenic activity of two designer self-assembling peptide scaffold hydrogels in the chicken embryo chorioallantoic membrane journal January 2012
Engineering bone-like tissuein vitro using human bone marrow stem cells and silk scaffolds journal January 2004
Chiral Supramolecular Polymers Formed by Host−Guest Interactions journal March 2005
Recombinant DNA production of spider silk proteins: Recombinant spider silks journal October 2013
The Mechanical Hierarchies of Fibronectin Observed with Single-molecule AFM journal May 2002
Nanostructured Hydrogels for Three-Dimensional Cell Culture Through Self-Assembly of Fluorenylmethoxycarbonyl–Dipeptides journal March 2006
Vitronectin—A major cell attachment-promoting protein in fetal bovine serum journal October 1985
Physical and chemical aspects of stabilization of compounds in silk journal January 2012
Spider Silk: From Soluble Protein to Extraordinary Fiber journal May 2009
Biocatalytic induction of supramolecular order journal October 2010
Supramolecular self-assemblies as functional nanomaterials journal January 2013
Functionalized silk-based biomaterials for bone formation journal January 2000
Multi-hierarchical self-assembly of a collagen mimetic peptide from triple helix to nanofibre and hydrogel journal August 2011
Immune response to biologic scaffold materials journal April 2008
Drug release from hydrazone-containing peptide amphiphiles journal January 2011
Extracellular Matrix Molecules: Potential Targets in Pharmacotherapy journal June 2009
Fibronectin and Other Adhesive Glycoproteins book December 2010
Synthesis and Characterization of Cell-Adhesive Silk-Like Proteins Constructed from the Sequences of Anaphe Silk Fibroin and Fibronectin journal April 2009
Porous 3-D Scaffolds from Regenerated Silk Fibroin journal May 2004
Sonic Hedgehog Is Neuroprotective in the Cavernous Nerve with Crush Injury journal May 2013
Silk Fibroin in Tissue Engineering journal June 2012
NMR Study of the Structures of Repeated Sequences, GAGXGA (X = S, Y, V), in Bombyx mori Liquid Silk journal December 2013
A Metal-Collagen Peptide Framework for Three-Dimensional Cell Culture journal October 2009
Reactions to a bovine collagen implant journal December 1989
A modular and supramolecular approach to bioactive scaffolds for tissue engineering journal June 2005
Aligned neurite outgrowth and directed cell migration in self-assembled monodomain gels journal January 2014
Spider Silk:  Ancient Ideas for New Biomaterials journal September 2006
Post-Assembly Functionalization of Supramolecular Nanostructures with Bioactive Peptides and Fluorescent Proteins by Native Chemical Ligation journal March 2014
Ligand Binding to Integrins journal May 2000
A Self-Assembled Nanofiber Catalyst for Ester Hydrolysis journal October 2007
Altered rate of fibronectin matrix assembly by deletion of the first type III repeats journal July 1996
Organ engineering based on decellularized matrix scaffolds journal August 2011
Molecular Structure of RADA16-I Designer Self-Assembling Peptide Nanofibers journal August 2013
Integrins: Versatility, modulation, and signaling in cell adhesion journal April 1992
A Supramolecular System for the Electrochemically Controlled Release of Cells journal November 2012
Surprising strength of silkworm silk journal August 2002
Tissue Cells Feel and Respond to the Stiffness of Their Substrate journal November 2005
Photoconductive Coaxial Nanotubes of Molecularly Connected Electron Donor and Acceptor Layers journal December 2006
Molecular Simulation Study of Peptide Amphiphile Self-Assembly journal February 2008
Dynamic Display of Bioactivity through Host-Guest Chemistry journal September 2013
25th Anniversary Article: Supramolecular Materials for Regenerative Medicine journal February 2014
Interfacial Self-Assembly of Cell-like Filamentous Microcapsules journal May 2011
Fibronectin-integrin interactions journal January 1997
Bioactive DNA-Peptide Nanotubes Enhance the Differentiation of Neural Stem Cells Into Neurons journal December 2014
Proteoglycans: from structural compounds to signaling molecules journal June 2009
Self-assembled peptide-based hydrogels as scaffolds for anchorage-dependent cells journal May 2009
Spider silk proteins: recent advances in recombinant production, structure–function relationships and biomedical applications journal July 2010
Supramolecular Polymers journal December 2001
Bioprintable, cell-laden silk fibroin–gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of three-dimensional tissue constructs journal January 2015
Cell adhesion and proliferation on RGD-modified recombinant spider silk proteins journal October 2012
Self-Assembled Multivalency: Dynamic Ligand Arrays for High-Affinity Binding journal June 2012
What makes spider silk fibers so strong? From molecular-crystallite network to hierarchical network structures journal December 2013
Supramolecular Polymer Formation by Metal−Ligand Complexation:  Monte Carlo Simulations and Analytical Modeling journal November 2004
Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system journal January 2015

Cited By (10)

Self-Assembled Peptide-Based Nanomaterials for Biomedical Imaging and Therapy journal February 2018
Engineering responsive supramolecular biomaterials: Toward smart therapeutics journal September 2016
Dynamic Hydrogels from Host-Guest Supramolecular Interactions journal October 2018
Leveraging advances in biology to design biomaterials journal December 2017
Photo-controlled reversible secondary self-assembly of supramolecular nanosheets and their drug delivery behavior journal January 2019
The past, present and future of protein-based materials journal October 2018
Microfluidic approaches for probing amyloid assembly and behaviour. text January 2018
Microfluidic approaches for probing amyloid assembly and behaviour journal January 2018
Production of protein-based polymers in Pichia pastoris journal September 2019
Reversible Transformation of a Supramolecular Hydrogel by Redox Switching of Methylene Blue—A Noncovalent Chain Stopper journal December 2019