skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering

Journal Article · · ChemComm
DOI:https://doi.org/10.1039/c7cc02733h· OSTI ID:1369304

In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. Finally, these results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.

Research Organization:
Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA)
Grant/Contract Number:
AC04-94AL85000
OSTI ID:
1369304
Report Number(s):
SAND-2017-6779J; CHCOFS; 654840
Journal Information:
ChemComm, Vol. 53, Issue 59; ISSN 1359-7345
Publisher:
Royal Society of ChemistryCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 21 works
Citation information provided by
Web of Science

References (43)

Role of partially amorphous structure and alloying elements on the corrosion behavior of Mg–Zn–Ca bulk metallic glass for biomedical applications journal December 2015
Cytotoxicity of zinc in vitro journal January 1989
Effects of secondary phase and grain size on the corrosion of biodegradable Mg–Zn–Ca alloys journal March 2015
MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants journal September 2009
Pd–Ni–Cu–P metallic glass nanowires for methanol and ethanol oxidation in alkaline media journal August 2013
Corrosion of, and cellular responses to Mg–Zn–Ca bulk metallic glasses journal February 2010
The effect of zinc on the biocompatibility of dental amalgams in vitro journal September 1984
Combinatorial development of bulk metallic glasses journal April 2014
Mg-based bulk metallic glasses for biodegradable implant materials: A review on glass forming ability, mechanical properties, and biocompatibility journal October 2015
Mechanical properties, degradation performance and cytotoxicity of Mg–Zn–Ca biomedical alloys with different compositions journal December 2011
In vitro degradation and electrochemical corrosion evaluations of microarc oxidized pure Mg, Mg–Ca and Mg–Ca–Zn alloys for biomedical applications journal February 2015
Effects of Zn on the microstructure, mechanical property and bio-corrosion property of Mg–3Ca alloys for biomedical application journal February 2011
In-vitro evaluation of Mg-4.0Zn-0.2Ca alloy for biomedical application journal August 2011
Biocompatibility of a novel zinc stent with a closed-cell-design journal September 2015
Guided Evolution of Bulk Metallic Glass Nanostructures: A Platform for Designing 3D Electrocatalytic Surfaces journal December 2015
Corrosion and related mechanical properties of bulk metallic glasses journal September 2006
Combinatorial screening of Pd-based quaternary electrocatalysts for oxygen reduction reaction in alkaline media journal January 2017
Preparation and characterization of a new biomedical Mg–Zn–Ca alloy journal February 2012
Glass forming ability and thermal stability of ternary Ca–Mg–Zn bulk metallic glasses journal October 2005
Examining the elemental contribution towards the biodegradation of Mg–Zn–Ca ternary metallic glasses journal January 2016
Metallic glass nanostructures of tunable shape and composition journal April 2015
Preparation and in vitro degradation of the composite coating with high adhesion strength on biodegradable Mg–Zn–Ca alloy journal December 2011
Influence of Ca and Zn on the microstructure and corrosion of biodegradable Mg–Ca–Zn alloys journal April 2015
Improved mechanical performance and delayed corrosion phenomena in biodegradable Mg–Zn–Ca alloys through Pd-alloying journal February 2012
Potentiodynamic polarisation study of bulk metallic glasses based on the Mg–Zn–Ca ternary system journal August 2012
Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation journal September 2011
Recent advances in bulk metallic glasses for biomedical applications journal May 2016
Metallic glass thin films for potential biomedical applications: Metallic Glass Thin Films For Potential Biomedical Applications
  • Kaushik, Neelam; Sharma, Parmanand; Ahadian, Samad
  • Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 102, Issue 7 https://doi.org/10.1002/jbm.b.33135
journal March 2014
Biodegradable CaMgZn bulk metallic glass for potential skeletal application journal August 2011
In vitro and in vivo corrosion measurements of magnesium alloys journal March 2006
Opportunities and challenges for the biodegradable magnesium alloys as next-generation biomaterials journal March 2016
Microstructure and bio-corrosion behavior of Mg-Zn and Mg-Zn-Ca alloys for biomedical applications: Microstructure and bio-corrosion behavior of Mg-Zn and Mg-Zn-Ca alloys journal March 2014
Processing of Bulk Metallic Glass journal December 2009
Solidification of Au-Cu-Si alloys investigated by a combinatorial approach journal June 2012
Bulk Metallic Glass Nanowire Architecture for Electrochemical Applications journal March 2011
Dissolution and precipitation behaviors of silicon-containing ceramic coating on Mg–Zn–Ca alloy in simulated body fluid journal October 2014
Relationship between the corrosion behavior and the thermal characteristics and microstructure of Mg–0.5Ca–xZn alloys journal November 2012
Crystallization behavior upon heating and cooling in Cu50Zr50 metallic glass thin films journal December 2016
Corrosion Resistance of Ag-ion Implanted Mg-Ca-Zn Alloys in SBF journal December 2010
Bulk Metallic Glass Micro Fuel Cell journal November 2012
In vitro corrosion behaviors of Mg67Zn28Ca5 alloy: From amorphous to crystalline journal June 2012
Ca–Mg–Zn bulk metallic glasses as bioresorbable metals journal July 2012
Combinatorial exploration of color in gold-based alloys journal August 2015

Cited By (5)

Recent Advances in Metallic Glass Nanostructures: Synthesis Strategies and Electrocatalytic Applications journal December 2018
Formation and stability of complex metallic phases including quasicrystals explored through combinatorial methods journal May 2019
Accelerated discovery and mechanical property characterization of bioresorbable amorphous alloys in the Mg–Zn–Ca and the Fe–Mg–Zn systems using high-throughput methods journal January 2019
Review on Quantum Mechanically Guided Design of Ultra-Strong Metallic Glasses journal April 2020
Review on Quantum Mechanically Guided Design of Ultra-Strong Metallic Glasses text January 2020

Similar Records

The synthesis and characterization of Mg-Zn-Ca alloy by powder metallurgy process
Journal Article · Tue Apr 19 00:00:00 EDT 2016 · AIP Conference Proceedings · OSTI ID:1369304

Combinatorial sputtering of Ga-doped (Zn,Mg)O for contact applications in solar cells
Journal Article · Tue Sep 20 00:00:00 EDT 2016 · Solar Energy Materials and Solar Cells · OSTI ID:1369304

Surface Structure and Corrosion Behavior of Mg{sub 68−x}Zn{sub 28+x}Ca{sub 4}(x = 0.4) Bulk Metallic Glasses after Immersion in Ringer’s Solution
Journal Article · Mon Apr 01 00:00:00 EDT 2019 · Journal of Materials Engineering and Performance · OSTI ID:1369304

Related Subjects