Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering

Li, Jinyang; Gittleson, Forrest S.; Liu, Yanhui; Liu, Jingbei; Loye, Ayomiposi M.; McMillon-Brown, Lyndsey; Kyriakides, Themis R.; Schroers, Jan; Taylor, Andre D.

doi:10.1039/c7cc02733h

Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering

Journal Article · Fri Jun 30 04:00:00 EDT 2017 · ChemComm

DOI:https://doi.org/10.1039/c7cc02733h· OSTI ID:1369304

^[1]; ^[2]; Liu, Yanhui ^[1]; Liu, Jingbei ^[1]; Loye, Ayomiposi M. ^[1]; McMillon-Brown, Lyndsey ^[1]; Kyriakides, Themis R. ^[1]; Schroers, Jan ^[1]; Taylor, Andre D. ^[1]

Yale Univ., New Haven, CT (United States)
Sandia National Lab. (SNL-CA), Livermore, CA (United States)

In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. Finally, these results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.

View Accepted Manuscript (DOE)

Research Organization:: Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA)

Grant/Contract Number:: AC04-94AL85000

OSTI ID:: 1369304

Report Number(s):: SAND--2017-6779J; 654840

Journal Information:: ChemComm, Journal Name: ChemComm Journal Issue: 59 Vol. 53; ISSN CHCOFS; ISSN 1359-7345

Publisher:: Royal Society of ChemistryCopyright Statement

Country of Publication:: United States

Language:: English

References (43)

Processing of Bulk Metallic Glass Schroers, Jan Advanced Materials, Vol. 22, Issue 14 https://doi.org/10.1002/adma.200902776	journal	December 2009
Guided Evolution of Bulk Metallic Glass Nanostructures: A Platform for Designing 3D Electrocatalytic Surfaces Doubek, Gustavo; Sekol, Ryan C.; Li, Jinyang Advanced Materials, Vol. 28, Issue 10 https://doi.org/10.1002/adma.201504504	journal	December 2015
Metallic glass thin films for potential biomedical applications: Metallic Glass Thin Films For Potential Biomedical Applications Kaushik, Neelam; Sharma, Parmanand; Ahadian, Samad Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 102, Issue 7 https://doi.org/10.1002/jbm.b.33135	journal	March 2014
Microstructure and bio-corrosion behavior of Mg-Zn and Mg-Zn-Ca alloys for biomedical applications: Microstructure and bio-corrosion behavior of Mg-Zn and Mg-Zn-Ca alloys Bakhsheshi-Rad, H. R.; Hamzah, E.; Fereidouni-Lotfabadi, A. Materials and Corrosion, Vol. 65, Issue 12 https://doi.org/10.1002/maco.201307588	journal	March 2014
Bulk Metallic Glass Micro Fuel Cell Sekol, Ryan C.; Kumar, Golden; Carmo, Marcelo Small, Vol. 9, Issue 12 https://doi.org/10.1002/smll.201201647	journal	November 2012
Combinatorial exploration of color in gold-based alloys Liu, Jingbei; Liu, Yanhui; Gong, Pan Gold Bulletin, Vol. 48, Issue 3-4 https://doi.org/10.1007/s13404-015-0167-z	journal	August 2015
Cytotoxicity of zinc in vitro Borovanský, Jan; Riley, Patrick A. Chemico-Biological Interactions, Vol. 69, Issue 2-3 https://doi.org/10.1016/0009-2797(89)90085-9	journal	January 1989
The effect of zinc on the biocompatibility of dental amalgams in vitro Meryon, S. D. Biomaterials, Vol. 5, Issue 5 https://doi.org/10.1016/0142-9612(84)90076-0	journal	September 1984
In-vitro evaluation of Mg-4.0Zn-0.2Ca alloy for biomedical application Sun, Yu; Kong, Min-xiu; Jiao, Xiao-hui Transactions of Nonferrous Metals Society of China, Vol. 21 https://doi.org/10.1016/S1003-6326(11)61587-2	journal	August 2011
Corrosion Resistance of Ag-ion Implanted Mg-Ca-Zn Alloys in SBF Lihe, Mao; Yulin, Wang; Yizao, Wan Rare Metal Materials and Engineering, Vol. 39, Issue 12 https://doi.org/10.1016/S1875-5372(11)60002-7	journal	December 2010
Crystallization behavior upon heating and cooling in Cu50Zr50 metallic glass thin films Lee, Dongwoo; Zhao, Bingge; Perim, Eric Acta Materialia, Vol. 121 https://doi.org/10.1016/j.actamat.2016.08.076	journal	December 2016
Biodegradable CaMgZn bulk metallic glass for potential skeletal application Wang, Y. B.; Xie, X. H.; Li, H. F. Acta Biomaterialia, Vol. 7, Issue 8 https://doi.org/10.1016/j.actbio.2011.04.027	journal	August 2011
Mechanical and corrosion properties of newly developed biodegradable Zn-based alloys for bone fixation Vojtěch, D.; Kubásek, J.; Šerák, J. Acta Biomaterialia, Vol. 7, Issue 9 https://doi.org/10.1016/j.actbio.2011.05.008	journal	September 2011
Ca–Mg–Zn bulk metallic glasses as bioresorbable metals Cao, J. D.; Kirkland, N. T.; Laws, K. J. Acta Biomaterialia, Vol. 8, Issue 6 https://doi.org/10.1016/j.actbio.2012.03.009	journal	July 2012
Recent advances in bulk metallic glasses for biomedical applications Li, H. F.; Zheng, Y. F. Acta Biomaterialia, Vol. 36 https://doi.org/10.1016/j.actbio.2016.03.047	journal	May 2016
In vitro and in vivo corrosion measurements of magnesium alloys Witte, Frank; Fischer, Jens; Nellesen, Jens Biomaterials, Vol. 27, Issue 7 https://doi.org/10.1016/j.biomaterials.2005.07.037	journal	March 2006
Corrosion of, and cellular responses to Mg–Zn–Ca bulk metallic glasses Gu, Xuenan; Zheng, Yufeng; Zhong, Shengping Biomaterials, Vol. 31, Issue 6 https://doi.org/10.1016/j.biomaterials.2009.11.015	journal	February 2010
Dissolution and precipitation behaviors of silicon-containing ceramic coating on Mg–Zn–Ca alloy in simulated body fluid Pan, Yaokun; Chen, Chuanzhong; Wang, Diangang Colloids and Surfaces B: Biointerfaces, Vol. 122 https://doi.org/10.1016/j.colsurfb.2014.08.012	journal	October 2014
Relationship between the corrosion behavior and the thermal characteristics and microstructure of Mg–0.5Ca–xZn alloys Bakhsheshi-Rad, H. R.; Abdul-Kadir, M. R.; Idris, M. H. Corrosion Science, Vol. 64 https://doi.org/10.1016/j.corsci.2012.07.015	journal	November 2012
Influence of Ca and Zn on the microstructure and corrosion of biodegradable Mg–Ca–Zn alloys Zander, Daniela; Zumdick, Naemi A. Corrosion Science, Vol. 93 https://doi.org/10.1016/j.corsci.2015.01.027	journal	April 2015
Pd–Ni–Cu–P metallic glass nanowires for methanol and ethanol oxidation in alkaline media Sekol, Ryan C.; Carmo, Marcelo; Kumar, Golden International Journal of Hydrogen Energy, Vol. 38, Issue 26 https://doi.org/10.1016/j.ijhydene.2013.06.017	journal	August 2013
Improved mechanical performance and delayed corrosion phenomena in biodegradable Mg–Zn–Ca alloys through Pd-alloying González, S.; Pellicer, E.; Fornell, J. Journal of the Mechanical Behavior of Biomedical Materials, Vol. 6 https://doi.org/10.1016/j.jmbbm.2011.09.014	journal	February 2012
Glass forming ability and thermal stability of ternary Ca–Mg–Zn bulk metallic glasses Senkov, O. N.; Scott, J. M. Journal of Non-Crystalline Solids, Vol. 351, Issue 37-39 https://doi.org/10.1016/j.jnoncrysol.2005.07.022	journal	October 2005
Mg-based bulk metallic glasses for biodegradable implant materials: A review on glass forming ability, mechanical properties, and biocompatibility Dambatta, M. S.; Izman, S.; Yahaya, B. Journal of Non-Crystalline Solids, Vol. 426 https://doi.org/10.1016/j.jnoncrysol.2015.07.018	journal	October 2015
Preparation and in vitro degradation of the composite coating with high adhesion strength on biodegradable Mg–Zn–Ca alloy Li, Wen; Guan, Shaokang; Chen, Juan Materials Characterization, Vol. 62, Issue 12 https://doi.org/10.1016/j.matchar.2011.07.005	journal	December 2011
Effects of Zn on the microstructure, mechanical property and bio-corrosion property of Mg–3Ca alloys for biomedical application Du, Hui; Wei, Zunjie; Liu, Xinwang Materials Chemistry and Physics, Vol. 125, Issue 3 https://doi.org/10.1016/j.matchemphys.2010.10.015	journal	February 2011
In vitro corrosion behaviors of Mg67Zn28Ca5 alloy: From amorphous to crystalline Wang, Yongsheng; Tan, Ming Jen; Pang, Jianjun Materials Chemistry and Physics, Vol. 134, Issue 2-3 https://doi.org/10.1016/j.matchemphys.2012.03.116	journal	June 2012
Preparation and characterization of a new biomedical Mg–Zn–Ca alloy Sun, Yu; Zhang, Baoping; Wang, Yin Materials & Design, Vol. 34 https://doi.org/10.1016/j.matdes.2011.07.058	journal	February 2012
Role of partially amorphous structure and alloying elements on the corrosion behavior of Mg–Zn–Ca bulk metallic glass for biomedical applications Ramya, M.; Sarwat, Syed Ghazi; Udhayabanu, V. Materials & Design, Vol. 86 https://doi.org/10.1016/j.matdes.2015.07.154	journal	December 2015
Mechanical properties, degradation performance and cytotoxicity of Mg–Zn–Ca biomedical alloys with different compositions Zhang, Baoping; Hou, Yunlong; Wang, Xiaodan Materials Science and Engineering: C, Vol. 31, Issue 8 https://doi.org/10.1016/j.msec.2011.07.015	journal	December 2011
In vitro degradation and electrochemical corrosion evaluations of microarc oxidized pure Mg, Mg–Ca and Mg–Ca–Zn alloys for biomedical applications Pan, Yaokun; He, Siyu; Wang, Diangang Materials Science and Engineering: C, Vol. 47 https://doi.org/10.1016/j.msec.2014.11.048	journal	February 2015
Effects of secondary phase and grain size on the corrosion of biodegradable Mg–Zn–Ca alloys Lu, Y.; Bradshaw, A. R.; Chiu, Y. L. Materials Science and Engineering: C, Vol. 48 https://doi.org/10.1016/j.msec.2014.12.049	journal	March 2015
Bulk Metallic Glass Nanowire Architecture for Electrochemical Applications Carmo, Marcelo; Sekol, Ryan C.; Ding, Shiyan ACS Nano, Vol. 5, Issue 4 https://doi.org/10.1021/nn200033c	journal	March 2011
Metallic glass nanostructures of tunable shape and composition Liu, Yanhui; Liu, Jingbei; Sohn, Sungwoo Nature Communications, Vol. 6, Issue 1 https://doi.org/10.1038/ncomms8043	journal	April 2015
MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants Zberg, Bruno; Uggowitzer, Peter J.; Löffler, Jörg F. Nature Materials, Vol. 8, Issue 11 https://doi.org/10.1038/nmat2542	journal	September 2009
Combinatorial development of bulk metallic glasses Ding, Shiyan; Liu, Yanhui; Li, Yanglin Nature Materials, Vol. 13, Issue 5 https://doi.org/10.1038/nmat3939	journal	April 2014
Combinatorial screening of Pd-based quaternary electrocatalysts for oxygen reduction reaction in alkaline media Li, Jinyang; Stein, Helge S.; Sliozberg, Kirill Journal of Materials Chemistry A, Vol. 5, Issue 1 https://doi.org/10.1039/C6TA08088J	journal	January 2017
Examining the elemental contribution towards the biodegradation of Mg–Zn–Ca ternary metallic glasses Miskovic, D. M.; Pohl, K.; Birbilis, N. Journal of Materials Chemistry B, Vol. 4, Issue 15 https://doi.org/10.1039/C6TB00342G	journal	January 2016
Solidification of Au-Cu-Si alloys investigated by a combinatorial approach Ding, Shiyan; Gregoire, John; Vlassak, Joost J. Journal of Applied Physics, Vol. 111, Issue 11 https://doi.org/10.1063/1.4722996	journal	June 2012
Opportunities and challenges for the biodegradable magnesium alloys as next-generation biomaterials Ding, Wenjiang Regenerative Biomaterials, Vol. 3, Issue 2 https://doi.org/10.1093/rb/rbw003	journal	March 2016
Potentiodynamic polarisation study of bulk metallic glasses based on the Mg–Zn–Ca ternary system Cao, J. D.; Laws, K. J.; Birbilis, N. Corrosion Engineering, Science and Technology, Vol. 47, Issue 5 https://doi.org/10.1179/1743278212Y.0000000016	journal	August 2012
Corrosion and related mechanical properties of bulk metallic glasses Scully, John R.; Gebert, A.; Payer, Joe H. Journal of Materials Research, Vol. 22, Issue 2 https://doi.org/10.1557/jmr.2007.0051	journal	September 2006
Biocompatibility of a novel zinc stent with a closed-cell-design Hiebl, Bernhard; Nennig, Ernst; Schiestel, Stefanie Clinical Hemorheology and Microcirculation, Vol. 61, Issue 2 https://doi.org/10.3233/CH-151983	journal	September 2015

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Accelerated discovery and mechanical property characterization of bioresorbable amorphous alloys in the Mg–Zn–Ca and the Fe–Mg–Zn systems using high-throughput methods Datye, Amit; Alexander Kube, Sebastian; Verma, Devendra Journal of Materials Chemistry B, Vol. 7, Issue 35 https://doi.org/10.1039/c9tb01302d	journal	January 2019
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