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Title: Synthesis of new water-soluble metal-binding polymers: Combinatorial chemistry approach. 1998 annual progress report

Abstract

'(1) Develop rapid discovery and optimization approaches to new water-soluble chelating polymers for use in Polymer Filtration (PF) systems, and (2) evaluate the concept of using water and organic soluble polymers as new solid supports for combinatorial synthesis. Polymer Filtration (PF), which uses water-soluble metal-binding polymers to sequester metal ions in dilute solution with ultrafiltration (UF) to separate the polymers, is a new technology to selectively remove or recover hazardous and valuable metal ions. Future directions in PF must include rapid development, testing, and characterization of new metal-binding polymers. Thus, the authors are building upon and adapting the combinatorial chemistry approach developed for rapid molecule generation for the drug industry to the rapid development of new chelating polymers. The authors have focused on four areas including the development of: (1) synthetic procedures, (2) small ultrafiltration equipment compatible with organic- and aqueous-based combinatorial synthesis, (3) rapid assay techniques, and (4) polymer characterization techniques.'

Authors:
 [1]; ;  [2];  [3]
  1. Los Alamos National Lab., NM (US)
  2. Univ. of California, Davis, CA (US)
  3. Univ. of Massachusetts, Lowell, MA (US)
Publication Date:
Research Org.:
Los Alamos National Lab., NM (US)
Sponsoring Org.:
USDOE Office of Environmental Management (EM), Office of Science and Risk Policy
OSTI Identifier:
13631
Report Number(s):
EMSP-54724-98
ON: DE00013631
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
40; 05; 54; Progress Report; Solid Solutions; Chemical Reactions; Decontamination; Decommissioning; High-Level Radioactive Wastes; Radioactive Wastes; Chemical Wastes; Remedial Action; PROGRESS REPORT; SOLID SOLUTIONS; CHEMICAL REACTIONS; DECONTAMINATION; DECOMMISSIONING; HIGH-LEVEL RADIOACTIVE WASTES; RADIOACTIVE WASTES; CHEMICAL WASTES; REMEDIAL ACTION

Citation Formats

Smith, B F, Kurth, M J, Miller, R B, and Sawan, S. Synthesis of new water-soluble metal-binding polymers: Combinatorial chemistry approach. 1998 annual progress report. United States: N. p., 1998. Web. doi:10.2172/13631.
Smith, B F, Kurth, M J, Miller, R B, & Sawan, S. Synthesis of new water-soluble metal-binding polymers: Combinatorial chemistry approach. 1998 annual progress report. United States. doi:10.2172/13631.
Smith, B F, Kurth, M J, Miller, R B, and Sawan, S. Mon . "Synthesis of new water-soluble metal-binding polymers: Combinatorial chemistry approach. 1998 annual progress report". United States. doi:10.2172/13631. https://www.osti.gov/servlets/purl/13631.
@article{osti_13631,
title = {Synthesis of new water-soluble metal-binding polymers: Combinatorial chemistry approach. 1998 annual progress report},
author = {Smith, B F and Kurth, M J and Miller, R B and Sawan, S},
abstractNote = {'(1) Develop rapid discovery and optimization approaches to new water-soluble chelating polymers for use in Polymer Filtration (PF) systems, and (2) evaluate the concept of using water and organic soluble polymers as new solid supports for combinatorial synthesis. Polymer Filtration (PF), which uses water-soluble metal-binding polymers to sequester metal ions in dilute solution with ultrafiltration (UF) to separate the polymers, is a new technology to selectively remove or recover hazardous and valuable metal ions. Future directions in PF must include rapid development, testing, and characterization of new metal-binding polymers. Thus, the authors are building upon and adapting the combinatorial chemistry approach developed for rapid molecule generation for the drug industry to the rapid development of new chelating polymers. The authors have focused on four areas including the development of: (1) synthetic procedures, (2) small ultrafiltration equipment compatible with organic- and aqueous-based combinatorial synthesis, (3) rapid assay techniques, and (4) polymer characterization techniques.'},
doi = {10.2172/13631},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {6}
}