Identification of imidazo[1,2-b]pyridazine TYK2 pseudokinase ligands as potent and selective allosteric inhibitors of TYK2 signalling

Journal Article · Sat Dec 31 23:00:00 EST 2016 · MedChemComm

DOI:https://doi.org/10.1039/C6MD00560H· OSTI ID:1357628

Moslin, R.; Gardner, D.; Santella, J.; Zhang, Y.; Duncia, J. V.; Liu, C.; Lin, J.; Tokarski, J. S.; Strnad, J.; Pedicord, D.; Chen, J.; Blat, Y.; Zupa-Fernandez, A.; Cheng, L.; Sun, H.; Chaudhry, C.; Huang, C.; D'Arienzo, C.; Sack, J. S.; Muckelbauer, J. K. ; Chang, C.; Tredup, J.; Xie, D.; Aranibar, N.; Burke, J. R.; Carter, P. H.; Weinstein, D. S.

Abstract not provided

• Research Organization: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
• Sponsoring Organization: INDUSTRY
• OSTI ID: 1357628
• Journal Information: MedChemComm, Journal Name: MedChemComm Journal Issue: 4 Vol. 8; ISSN 2040-2503
• Publisher: Royal Society of Chemistry
• Country of Publication: United States
• Language: ENGLISH