Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1

Humphrey, John M.; Yang, Eddie; Ende, Christopher W.  am; Arnold, Eric P.; Head, Jenna L.; Jenkinson, Stephen; Lebel, Lorraine A.; Liras, Spiros; Pandit, Jayvardhan; Samas, Brian; Vajdos, Felix; Simons, Samuel P.; Evdokimov, Artem; Mansour, Mahmoud; Menniti, Frank S.

doi:10.1039/C4MD00113C

Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1

Journal Article · Wed Jan 01 04:00:00 EST 2014 · MedChemComm

DOI:https://doi.org/10.1039/C4MD00113C· OSTI ID:1346245

Humphrey, John M.; Yang, Eddie; Ende, Christopher W. am; Arnold, Eric P.; Head, Jenna L.; Jenkinson, Stephen; Lebel, Lorraine A.; Liras, Spiros; Pandit, Jayvardhan; Samas, Brian; Vajdos, Felix; Simons, Samuel P.; Evdokimov, Artem; Mansour, Mahmoud; Menniti, Frank S.

Abstract not provided

Research Organization:: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)

Sponsoring Organization:: USDOE Office of Science (SC)

OSTI ID:: 1346245

Journal Information:: MedChemComm, Journal Name: MedChemComm Journal Issue: 9 Vol. 5; ISSN 2040-2503

Publisher:: Royal Society of Chemistry

Country of Publication:: United States

Language:: ENGLISH

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