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Succinic anhydrides from epoxides

Patent ·
OSTI ID:1344776

Catalysts and methods for the double carbonylation of epoxides are disclosed. Each epoxide molecule reacts with two molecules of carbon monoxide to produce a succinic anhydride. The reaction is facilitated by catalysts combining a Lewis acidic species with a transition metal carbonyl complex. The double carbonylation is achieved in single process by using reaction conditions under which both carbonylation reactions occur without the necessity of isolating or purifying the product of the first carbonylation.

Research Organization:
Cornell University, Ithaca, NY (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-05ER15687
Assignee:
Cornell University (Ithaca, NY)
Patent Number(s):
9,376,413
Application Number:
14/552,825
OSTI ID:
1344776
Country of Publication:
United States
Language:
English

References (2)

Catalytic Double Carbonylation of Epoxides to Succinic Anhydrides:  Catalyst Discovery, Reaction Scope, and Mechanism
  • Rowley, John M.; Lobkovsky, Emil B.; Coates, Geoffrey W.
  • Journal of the American Chemical Society, Vol. 129, Issue 16, p. 4948-4960 https://doi.org/10.1021/ja066901a
journal April 2007
Catalytic Carbonylation of β-Lactones to Succinic Anhydrides
  • Getzler, Yutan D. Y. L.; Kundnani, Vinod; Lobkovsky, Emil B.
  • Journal of the American Chemical Society, Vol. 126, Issue 22, p. 6842-6843 https://doi.org/10.1021/ja048946m
journal June 2004

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