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Title: Can transition radiation explain the ANITA event 3985267?

Authors:
; ; ;
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1344192
Grant/Contract Number:
FG02-13ER41958; SC0009924
Resource Type:
Journal Article: Publisher's Accepted Manuscript
Journal Name:
Physical Review D
Additional Journal Information:
Journal Volume: 95; Journal Issue: 4; Related Information: CHORUS Timestamp: 2017-04-06 11:01:58; Journal ID: ISSN 2470-0010
Publisher:
American Physical Society
Country of Publication:
United States
Language:
English

Citation Formats

Motloch, Pavel, Alvarez-Muñiz, Jaime, Privitera, Paolo, and Zas, Enrique. Can transition radiation explain the ANITA event 3985267?. United States: N. p., 2017. Web. doi:10.1103/PhysRevD.95.043004.
Motloch, Pavel, Alvarez-Muñiz, Jaime, Privitera, Paolo, & Zas, Enrique. Can transition radiation explain the ANITA event 3985267?. United States. doi:10.1103/PhysRevD.95.043004.
Motloch, Pavel, Alvarez-Muñiz, Jaime, Privitera, Paolo, and Zas, Enrique. Fri . "Can transition radiation explain the ANITA event 3985267?". United States. doi:10.1103/PhysRevD.95.043004.
@article{osti_1344192,
title = {Can transition radiation explain the ANITA event 3985267?},
author = {Motloch, Pavel and Alvarez-Muñiz, Jaime and Privitera, Paolo and Zas, Enrique},
abstractNote = {},
doi = {10.1103/PhysRevD.95.043004},
journal = {Physical Review D},
number = 4,
volume = 95,
place = {United States},
year = {Fri Feb 17 00:00:00 EST 2017},
month = {Fri Feb 17 00:00:00 EST 2017}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record at 10.1103/PhysRevD.95.043004

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  • Observations of solar active regions reveal extensive areas of redshifted emission lines in the extreme ultraviolet, indicative of down flowing plasma. Redshifts are seen also in the magnetic network of the quiet sun and in magnetically active stars. The inferred velocities are large and appear to represent steady flows. Redshifts are not observed at higher coronal temperatures. It is shown here that steady flow in cool loops driven by the buoyancy force set up by a small heating asymmetry between the two legs of the loop, offers a possible theoretical explanation of the observed features. 27 refs.
  • Purpose: To study the impact of postoperative radiation therapy (PORT) on survival in the Adjuvant Navelbine International Trialist Association (ANITA) randomized study of adjuvant chemotherapy. Methods and Materials: ANITA is a randomized trial of adjuvant cisplatin and vinorelbine chemotherapy vs. observation in completely resected non-small-cell lung carcinoma (NSCLC) Stages IB to IIIA. Use of PORT was recommended for pN+ disease but was not randomized or mandatory. Each center decided whether to use PORT before initiation of the study. We describe here the survival of patients with and without PORT within each treatment group of ANITA. No statistical comparison of survivalmore » was performed because this was an unplanned subgroup analysis. Results: Overall, 232 of 840 patients received PORT (33.3% in the observation arm and 21.6% in the chemotherapy arm). In univariate analysis, PORT had a deleterious effect on the overall population survival. Patients with pN1 disease had an improved survival from PORT in the observation arm (median survival [MS] 25.9 vs. 50.2 months), whereas PORT had a detrimental effect in the chemotherapy group (MS 93.6 months and 46.6 months). In contrast, survival was improved in patients with pN2 disease who received PORT, both in the chemotherapy (MS 23.8 vs. 47.4 months) and observation arm (median 12.7 vs. 22.7 months). Conclusion: This retrospective evaluation suggests a positive effect of PORT in pN2 disease and a negative effect on pN1 disease when patients received adjuvant chemotherapy. The results support further evaluation of PORT in prospectively randomized studies in completely resected pN2 NSCLC.« less
  • Mammalian cells have been classified as proficient (Mer/sup +/) or deficient (Mer/sup -/) in methyl excision repair in terms of their cytotoxic reactions to agents that form O/sup 6/-alkylguanine and their abilities to reactivate alkylated adenoviruses. O/sup 6/-Methylguanine (O/sup 6/MeGua) is considered to be a lethal, mutagenic, and carciogenic lesion. We measured the abilities of cell extracts to transfer the methyl group from an exogenous DNA containing O/sup 6/MeGua to acceptor protein. The constitutive level of acceptor activity was independent of the Mer phenotype and was approx. = 100,000 acceptor sites per cell. Treatment of cells with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) resultsmore » in a dose-dependent decrease in the acceptor activity in extracts because the rapid reaction between endogenous O/sup 6/MeGua and acceptor protein makes the latter unavailable for further reaction. Treatment of cells with multiple low doses of MNNG results in the enhanced production of O/sup 6/MeGua-accepting protein in levels 2.5-fold above the constitutive values for Mer/sup +/ tumor cells and to approx. = 1.5-fold for Mer/sup +/ fibroblasts or Mer/sup -/ simian virus 40-transformed cells. Such treatments reduce the activities in Mer/sup -/ tumor cells and Chinese hamster cells. We concluded; (i) estimates of O/sup 6/MeGua in cellular DNA shortly after treatment may be seriously in error because of the rapid repair of this lesion, and (ii) the adaptive resynthesis of acceptor protein, not its constitutive level, is the important correlate of cell resistance to methylating agents.« less