OpenMSI Arrayed Analysis Tools v2.0

Software · Tue Feb 07 05:00:00 EST 2017

OSTI ID:1343109

BOWEN, BENJAMIN; RUEBEL, OLIVER; DE ROND, TRISTAN; DE RAAD, MARKUS

Mass spectrometry imaging (MSI) enables high-resolution spatial mapping of biomolecules in samples and is a valuable tool for the analysis of tissues from plants and animals, microbial interactions, high-throughput screening, drug metabolism, and a host of other applications. This is accomplished by desorbing molecules from the surface on spatially defined locations, using a laser or ion beam. These ions are analyzed by a mass spectrometry and collected into a MSI 'image', a dataset containing unique mass spectra from the sampled spatial locations. MSI is used in a diverse and increasing number of biological applications. The OpenMSI Arrayed Analysis Tool (OMAAT) is a new software method that addresses the challenges of analyzing spatially defined samples in large MSI datasets, by providing support for automatic sample position optimization and ion selection.

• Short Name / Acronym: OpenMSI Arrayed Analysis Tools v2.0; 005135MLTPL00
• Site Accession Number: 2018-188
• Version: 00
• Programming Language(s): Medium: X; OS: N/A
• Research Organization: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
• Sponsoring Organization: USDOE
• Contributing Organization: LAWRENCE BERKELEY NATIONAL LABORATORY
• DOE Contract Number: AC02-05CH11231
• OSTI ID: 1343109
• Country of Origin: United States