Triacylglycerol Metabolism, Function, and Accumulation in Plant Vegetative Tissues

Xu, Changcheng; Shanklin, John

doi:10.1146/annurev-arplant-043015-111641

Title: Triacylglycerol Metabolism, Function, and Accumulation in Plant Vegetative Tissues

Journal Article · Wed Feb 03 00:00:00 EST 2016 · Annual Review of Plant Biology

DOI:https://doi.org/10.1146/annurev-arplant-043015-111641· OSTI ID:1335392

Xu, Changcheng ^[1]; Shanklin, John ^[1]

Brookhaven National Lab. (BNL), Upton, NY (United States). Biology Dept.

One of the most abundant energy-dense storage compounds in eukaryotes are oils in the form of triacylglycerols , and their metabolism plays a key role in cellular energy balance, lipid homeostasis, growth, and maintenance. Plants accumulate oils primarily in seeds and fruits. Moreover, plant oils are used for food and feed and, increasingly, as feedstocks for biodiesel and industrial chemicals. Although plant vegetative tissues do not accumulate significant levels of triacylglycerols, they possess a high capacity for their synthesis, storage, and metabolism. The development of plants that accumulate oil in vegetative tissues presents an opportunity for expanded production of triacylglycerols as a renewable and sustainable bioenergy source. We review recent progress in the understanding of triacylglycerol synthesis, turnover, storage, and function in leaves and discuss emerging genetic engineering strategies targeted at enhancing triacylglycerol accumulation in biomass crops. Such plants could potentially be modified to produce oleochemical feedstocks or nutraceuticals.

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Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC00112704; DOE KC0304000

OSTI ID:: 1335392

Report Number(s):: BNL-111805-2016-JA; R&D Project: FWP# BO163; KC0304020

Journal Information:: Annual Review of Plant Biology, Vol. 67, Issue 1; ISSN 1543-5008

Publisher:: Annual ReviewsCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 170 works

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References (193)

The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets Adeyo, Oludotun; Horn, Patrick J.; Lee, SungKyung The Journal of Cell Biology, Vol. 192, Issue 6, p. 1043-1055 https://doi.org/10.1083/jcb.201010111	journal	March 2011
Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus Andre, C.; Haslam, R. P.; Shanklin, J. Proceedings of the National Academy of Sciences, Vol. 109, Issue 25 https://doi.org/10.1073/pnas.1204604109	journal	June 2012
Tobacco as a production platform for biofuel overexpression of Arabidopsis DGAT and LEC2 genes increases accumulation and shifts the composition of lipids in green biomass Andrianov, Vyacheslav; Borisjuk, Nikolai; Pogrebnyak, Natalia Plant Biotechnology Journal, Vol. 8, Issue 3, p. 277-287 https://doi.org/10.1111/j.1467-7652.2009.00458.x	journal	April 2010
Tgl4p and Tgl5p, Two Triacylglycerol Lipases of the Yeast Saccharomyces cerevisiae Are Localized to Lipid Particles Athenstaedt, Karin; Daum, Günther Journal of Biological Chemistry, Vol. 280, Issue 45 https://doi.org/10.1074/jbc.M507261200	journal	August 2005
RD20, a Stress-Inducible Caleosin, Participates in Stomatal Control, Transpiration and Drought Tolerance in Arabidopsis thaliana Aubert, Yann; Vile, Denis; Pervent, Marjorie Plant and Cell Physiology, Vol. 51, Issue 12 https://doi.org/10.1093/pcp/pcq155	journal	October 2010
Lipid droplet–organelle interactions: emerging roles in lipid metabolism Barbosa, Antonio Daniel; Savage, David B.; Siniossoglou, Symeon Current Opinion in Cell Biology, Vol. 35 https://doi.org/10.1016/j.ceb.2015.04.017	journal	August 2015
Controlling lipid accumulation in cereal grains Barthole, Guillaume; Lepiniec, Loïc; Rogowsky, Peter M. Plant Science, Vol. 185-186 https://doi.org/10.1016/j.plantsci.2011.09.002	journal	April 2012
The pathway of triacylglycerol synthesis through phosphatidylcholine in Arabidopsis produces a bottleneck for the accumulation of unusual fatty acids in transgenic seeds: PC is a bottleneck in HFA-TAG synthesis Bates, Philip D.; Browse, John The Plant Journal, Vol. 68, Issue 3 https://doi.org/10.1111/j.1365-313X.2011.04693.x	journal	August 2011
Analysis of Acyl Fluxes through Multiple Pathways of Triacylglycerol Synthesis in Developing Soybean Embryos Bates, Philip D.; Durrett, Timothy P.; Ohlrogge, John B. Plant Physiology, Vol. 150, Issue 1 https://doi.org/10.1104/pp.109.137737	journal	March 2009
Acyl Editing and Headgroup Exchange Are the Major Mechanisms That Direct Polyunsaturated Fatty Acid Flux into Triacylglycerols Bates, Philip D.; Fatihi, Abdelhak; Snapp, Anna R. Plant Physiology, Vol. 160, Issue 3 https://doi.org/10.1104/pp.112.204438	journal	August 2012
Incorporation of Newly Synthesized Fatty Acids into Cytosolic Glycerolipids in Pea Leaves Occurs via Acyl Editing Bates, Philip D.; Ohlrogge, John B.; Pollard, Mike Journal of Biological Chemistry, Vol. 282, Issue 43 https://doi.org/10.1074/jbc.M705447200	journal	August 2007
Biochemical pathways in seed oil synthesis Bates, Philip D.; Stymne, Sten; Ohlrogge, John Current Opinion in Plant Biology, Vol. 16, Issue 3 https://doi.org/10.1016/j.pbi.2013.02.015	journal	June 2013
PII is induced by WRINKLED1 and fine-tunes fatty acid composition in seeds of Arabidopsis thaliana: PII fine-tunes fatty acid composition in seeds Baud, Sébastien; Feria Bourrellier, Ana Belen; Azzopardi, Marianne The Plant Journal, Vol. 64, Issue 2 https://doi.org/10.1111/j.1365-313X.2010.04332.x	journal	September 2010
Regulation of de novo fatty acid synthesis in maturing oilseeds of Arabidopsis Baud, Sébastien; Lepiniec, Loïc Plant Physiology and Biochemistry, Vol. 47, Issue 6 https://doi.org/10.1016/j.plaphy.2008.12.006	journal	June 2009
Physiological and developmental regulation of seed oil production Baud, Sébastien; Lepiniec, Loïc Progress in Lipid Research, Vol. 49, Issue 3 https://doi.org/10.1016/j.plipres.2010.01.001	journal	July 2010
WRINKLED1 specifies the regulatory action of LEAFY COTYLEDON2 towards fatty acid metabolism during seed maturation in Arabidopsis: Oil synthesis regulatory network in seeds Baud, Sébastien; Mendoza, Monica Santos; To, Alexandra The Plant Journal, Vol. 50, Issue 5 https://doi.org/10.1111/j.1365-313X.2007.03092.x	journal	April 2007
COPI Complex Is a Regulator of Lipid Homeostasis Beller, Mathias; Sztalryd, Carole; Southall, Noel PLoS Biology, Vol. 6, Issue 11 https://doi.org/10.1371/journal.pbio.0060292	journal	November 2008
Synthesis of Phosphatidylcholine in the Chloroplast Envelope after Import of Lysophosphatidylcholine from Endoplasmic Reticulum Membranes Bessoule, Jean-Jacques; Testet, Eric; Cassagne, Claude European Journal of Biochemistry, Vol. 228, Issue 2 https://doi.org/10.1111/j.1432-1033.1995.tb20288.x	journal	March 1995
Lipid trafficking at endoplasmic reticulum–chloroplast membrane contact sites Block, Maryse A.; Jouhet, Juliette Current Opinion in Cell Biology, Vol. 35 https://doi.org/10.1016/j.ceb.2015.03.004	journal	August 2015
The CRISPR/Cas9 system for plant genome editing and beyond Bortesi, Luisa; Fischer, Rainer Biotechnology Advances, Vol. 33, Issue 1 https://doi.org/10.1016/j.biotechadv.2014.12.006	journal	January 2015
Chloroplast acetyl-CoA carboxylase activity is 2-oxoglutarate-regulated by interaction of PII with the biotin carboxyl carrier subunit Feria Bourrellier, A. B.; Valot, B.; Guillot, A. Proceedings of the National Academy of Sciences, Vol. 107, Issue 1 https://doi.org/10.1073/pnas.0910097107	journal	December 2009
Expression in yeast of an acyl-CoA:diacylglycerol acyltransferase cDNA from Caenorhabditis elegans Bouvier-Navé, P.; Benveniste, P.; Noiriel, A. Biochemical Society Transactions, Vol. 28, Issue 6 https://doi.org/10.1042/bst0280692	journal	December 2000
Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis: Gene expression in different types of senescence Buchanan-Wollaston, Vicky; Page, Tania; Harrison, Elizabeth The Plant Journal, Vol. 42, Issue 4 https://doi.org/10.1111/j.1365-313X.2005.02399.x	journal	April 2005
Arabidopsis SEIPIN Proteins Modulate Triacylglycerol Accumulation and Influence Lipid Droplet Proliferation Cai, Yingqi; Goodman, Joel M.; Pyc, Michal The Plant Cell, Vol. 27, Issue 9 https://doi.org/10.1105/tpc.15.00588	journal	September 2015
Replacing fossil oil with fresh oil - with what and for what? Carlsson, Anders S.; Yilmaz, Jenny Lindberg; Green, Allan G. European Journal of Lipid Science and Technology, Vol. 113, Issue 7 https://doi.org/10.1002/ejlt.201100032	journal	April 2011
Diacylglycerol, when simplicity becomes complex Carrasco, Silvia; Mérida, Isabel Trends in Biochemical Sciences, Vol. 32, Issue 1 https://doi.org/10.1016/j.tibs.2006.11.004	journal	January 2007
WRINKLED1 encodes an AP2/EREB domain protein involved in the control of storage compound biosynthesis in Arabidopsis Cernac, Alex; Benning, Christoph The Plant Journal, Vol. 40, Issue 4, p. 575-585 https://doi.org/10.1111/j.1365-313X.2004.02235.x	journal	September 2004
Biogenesis and functions of lipid droplets in plants: Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man Chapman, Kent D.; Dyer, John M.; Mullen, Robert T. Journal of Lipid Research, Vol. 53, Issue 2 https://doi.org/10.1194/jlr.R021436	journal	November 2011
Commentary: Why don’t plant leaves get fat? Chapman, Kent D.; Dyer, John M.; Mullen, Robert T. Plant Science, Vol. 207 https://doi.org/10.1016/j.plantsci.2013.03.003	journal	June 2013
Compartmentation of Triacylglycerol Accumulation in Plants Chapman, Kent D.; Ohlrogge, John B. Journal of Biological Chemistry, Vol. 287, Issue 4, p. 2288-2294 https://doi.org/10.1074/jbc.R111.290072	journal	November 2011
System Analysis of an Arabidopsis Mutant Altered in de Novo Fatty Acid Synthesis Reveals Diverse Changes in Seed Composition and Metabolism Chen, Mingjie; Mooney, Brian P.; Hajduch, Martin Plant Physiology, Vol. 150, Issue 1 https://doi.org/10.1104/pp.108.134882	journal	March 2009
PHOSPHATIDIC ACID PHOSPHOHYDROLASE Regulates Phosphatidylcholine Biosynthesis in Arabidopsis by Phosphatidic Acid-Mediated Activation of CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE Activity Craddock, Christian P.; Adams, Nicolette; Bryant, Fiona M. The Plant Cell, Vol. 27, Issue 4 https://doi.org/10.1105/tpc.15.00037	journal	April 2015
Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants Dahlqvist, A.; Stahl, U.; Lenman, M. Proceedings of the National Academy of Sciences, Vol. 97, Issue 12, p. 6487-6492 https://doi.org/10.1073/pnas.120067297	journal	May 2000
Localization of Seed Oil Body Proteins in Tobacco Protoplasts Reveals Specific Mechanisms of Protein Targeting to Leaf Lipid Droplets De Domenico, Stefania; Bonsegna, Stefania; Lenucci, Marcello Salvatore Journal of Integrative Plant Biology, Vol. 53, Issue 11 https://doi.org/10.1111/j.1744-7909.2011.01077.x	journal	November 2011
Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids De Marcos Lousa, Carine; van Roermund, Carlo W. T.; Postis, Vincent L. G. Proceedings of the National Academy of Sciences, Vol. 110, Issue 4, p. 1279-1284 https://doi.org/10.1073/pnas.1218034110	journal	January 2013
Overexpression of 3-Ketoacyl-Acyl-Carrier Protein Synthase IIIs in Plants Reduces the Rate of Lipid Synthesis Dehesh, Katayoon; Tai, Heeyoung; Edwards, Patricia Plant Physiology, Vol. 125, Issue 2 https://doi.org/10.1104/pp.125.2.1103	journal	February 2001
Plant triacylglycerols as feedstocks for the production of biofuels Durrett, Timothy P.; Benning, Christoph; Ohlrogge, John The Plant Journal, Vol. 54, Issue 4, p. 593-607 https://doi.org/10.1111/j.1365-313X.2008.03442.x	journal	May 2008
Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum Dwyer, Jennifer R.; Donkor, Jimmy; Zhang, Peixiang Proceedings of the National Academy of Sciences, Vol. 109, Issue 37 https://doi.org/10.1073/pnas.1205221109	journal	August 2012
SUGAR-DEPENDENT1 Encodes a Patatin Domain Triacylglycerol Lipase That Initiates Storage Oil Breakdown in Germinating Arabidopsis Seeds Eastmond, P. J. The Plant Cell Online, Vol. 18, Issue 3, p. 665-675 https://doi.org/10.1105/tpc.105.040543	journal	March 2006
PHOSPHATIDIC ACID PHOSPHOHYDROLASE1 and 2 Regulate Phospholipid Synthesis at the Endoplasmic Reticulum in Arabidopsis Eastmond, P. J.; Quettier, A.-L.; Kroon, J. T. M. The Plant Cell, Vol. 22, Issue 8, p. 2796-2811 https://doi.org/10.1105/tpc.109.071423	journal	August 2010
Expression of Lauroyl–Acyl Carrier Protein Thioesterase in Brassica napus Seeds Induces Pathways for Both Fatty Acid Oxidation and Biosynthesis and Implies a Set Point for Triacylglycerol Accumulation Eccleston, Victoria S.; Ohlrogge, John B. The Plant Cell, Vol. 10, Issue 4 https://doi.org/10.1105/tpc.10.4.613	journal	April 1998
Identification and characterization of a triacylglycerol lipase in Arabidopsis homologous to mammalian acid lipases El-Kouhen, Karim; Blangy, Stéphanie; Ortiz, Emilia FEBS Letters, Vol. 579, Issue 27 https://doi.org/10.1016/j.febslet.2005.09.072	journal	October 2005
Arabidopsis Lipins, PDAT1 Acyltransferase, and SDP1 Triacylglycerol Lipase Synergistically Direct Fatty Acids toward β-Oxidation, Thereby Maintaining Membrane Lipid Homeostasis Fan, Jilian; Yan, Chengshi; Roston, Rebecca The Plant Cell, Vol. 26, Issue 10 https://doi.org/10.1105/tpc.114.130377	journal	October 2014
Phospholipid:diacylglycerol acyltransferase-mediated triacylglycerol biosynthesis is crucial for protection against fatty acid-induced cell death in growing tissues of Arabidopsis Fan, Jilian; Yan, Chengshi; Xu, Changcheng The Plant Journal, Vol. 76, Issue 6, p. 930-942 https://doi.org/10.1111/tpj.12343	journal	November 2013
Dual Role for Phospholipid:Diacylglycerol Acyltransferase: Enhancing Fatty Acid Synthesis and Diverting Fatty Acids from Membrane Lipids to Triacylglycerol in Arabidopsis Leaves Fan, J.; Yan, C.; Zhang, X. The Plant Cell, Vol. 25, Issue 9, p. 3506-3518 https://doi.org/10.1105/tpc.113.117358	journal	September 2013
The role of transporters in supplying energy to plant plastids Flugge, U. -I.; Hausler, R. E.; Ludewig, F. Journal of Experimental Botany, Vol. 62, Issue 7 https://doi.org/10.1093/jxb/erq361	journal	April 2011
wrinkled1 : A Novel, Low-Seed-Oil Mutant of Arabidopsis with a Deficiency in the Seed-Specific Regulation of Carbohydrate Metabolism Focks, Nicole; Benning, Christoph Plant Physiology, Vol. 118, Issue 1 https://doi.org/10.1104/pp.118.1.91	journal	September 1998
Control of germination and lipid mobilization by COMATOSE, the Arabidopsis homologue of human ALDP Footitt, S. The EMBO Journal, Vol. 21, Issue 12 https://doi.org/10.1093/emboj/cdf300	journal	June 2002
Expression of the genes coding for plastidic acetyl-CoA carboxylase subunits is regulated by a location-sensitive transcription factor binding site Fukuda, Natsumi; Ikawa, Yuki; Aoyagi, Toshihiro Plant Molecular Biology, Vol. 82, Issue 4-5 https://doi.org/10.1007/s11103-013-0075-7	journal	June 2013
Two long-chain acyl-CoA synthetases from Arabidopsis thaliana involved in peroxisomal fatty acid β-oxidation Fulda, Martin; Shockey, Jay; Werber, Martin The Plant Journal, Vol. 32, Issue 1 https://doi.org/10.1046/j.1365-313X.2002.01405.x	journal	October 2002
A plastidial sodium-dependent pyruvate transporter Furumoto, Tsuyoshi; Yamaguchi, Teppei; Ohshima-Ichie, Yumiko Nature, Vol. 476, Issue 7361 https://doi.org/10.1038/nature10250	journal	August 2011
Regulation of Starch Biosynthesis in Response to a Fluctuating Environment Geigenberger, Peter Plant Physiology, Vol. 155, Issue 4 https://doi.org/10.1104/pp.110.170399	journal	March 2011
Redox regulation of carbon storage and partitioning in response to light and sugars Geigenberger, Peter; Kolbe, Anna; Tiessen, Axel Journal of Experimental Botany, Vol. 56, Issue 416 https://doi.org/10.1093/jxb/eri178	journal	April 2005
Requirement for 3-ketoacyl-CoA thiolase-2 in peroxisome development, fatty acid β-oxidation and breakdown of triacylglycerol in lipid bodies of Arabidopsis seedlings: A thiolase essential for seed lipid catabolism Germain, Véronique; Rylott, Elizabeth L.; Larson, Tony R. The Plant Journal, Vol. 28, Issue 1 https://doi.org/10.1046/j.1365-313X.2001.01095.x	journal	October 2001
At4g24160, a Soluble Acyl-Coenzyme A-Dependent Lysophosphatidic Acid Acyltransferase Ghosh, A. K.; Chauhan, N.; Rajakumari, S. Plant Physiology, Vol. 151, Issue 2, p. 869-881 https://doi.org/10.1104/pp.109.144261	journal	August 2009
Seed Storage Oil Mobilization Graham, Ian A. Annual Review of Plant Biology, Vol. 59, Issue 1, p. 115-142 https://doi.org/10.1146/annurev.arplant.59.032607.092938	journal	June 2008
Induction of Malate Synthase Gene Expression in Senescent and Detached Organs of Cucumber. Graham, I. A.; Leaver, C. J.; Smith, S. M. The Plant Cell https://doi.org/10.1105/tpc.4.3.349	journal	March 1992
Engineering increased triacylglycerol accumulation in Saccharomyces cerevisiae using a modified type 1 plant diacylglycerol acyltransferase Greer, Michael S.; Truksa, Martin; Deng, Wei Applied Microbiology and Biotechnology, Vol. 99, Issue 5 https://doi.org/10.1007/s00253-014-6284-4	journal	December 2014
Regulation of Starch Metabolism in Arabidopsis Leaves Grennan, Aleel K. Plant Physiology, Vol. 142, Issue 4 https://doi.org/10.1104/pp.104.900209	journal	December 2006
Transcriptional transitions in Nicotiana benthamiana leaves upon induction of oil synthesis by WRINKLED1 homologs from diverse species and tissues Grimberg, Åsa; Carlsson, Anders S.; Marttila, Salla BMC Plant Biology, Vol. 15, Issue 1 https://doi.org/10.1186/s12870-015-0579-1	journal	August 2015
Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila Grönke, Sebastian; Mildner, Alexander; Fellert, Sonja Cell Metabolism, Vol. 1, Issue 5 https://doi.org/10.1016/j.cmet.2005.04.003	journal	May 2005
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization Guo, Yi; Walther, Tobias C.; Rao, Meghana Nature, Vol. 453, Issue 7195 https://doi.org/10.1038/nature06928	journal	April 2008
Apparent induction of key enzymes of the glyoxylic acid cycle in senescent barley leaves Gut, Hans; Matile, Philippe Planta, Vol. 176, Issue 4 https://doi.org/10.1007/BF00397663	journal	January 1988
Dual function lipin proteins and glycerolipid metabolism Harris, Thurl E.; Finck, Brian N. Trends in Endocrinology & Metabolism, Vol. 22, Issue 6 https://doi.org/10.1016/j.tem.2011.02.006	journal	June 2011
2,4-Dichlorophenoxybutyric Acid–Resistant Mutants of Arabidopsis Have Defects in Glyoxysomal Fatty Acid β-Oxidation Hayashi, Makoto; Toriyama, Kanako; Kondo, Maki The Plant Cell, Vol. 10, Issue 2 https://doi.org/10.1105/tpc.10.2.183	journal	February 1998
A Gene Encoding an Acyl Hydrolase Is Involved in Leaf Senescence in Arabidopsis He, Yuehui; Gan, Susheng The Plant Cell, Vol. 14, Issue 4 https://doi.org/10.1105/tpc.010422	journal	April 2002
Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae Henry, Susan A.; Kohlwein, Sepp D.; Carman, George M. Genetics, Vol. 190, Issue 2, p. 317-349 https://doi.org/10.1534/genetics.111.130286	journal	February 2012
A Cytosolic Acyltransferase Contributes to Triacylglycerol Synthesis in Sucrose-Rescued Arabidopsis Seed Oil Catabolism Mutants Hernández, M. Luisa; Whitehead, Lynne; He, Zhesi Plant Physiology, Vol. 160, Issue 1 https://doi.org/10.1104/pp.112.201541	journal	July 2012
Identification of a New Class of Lipid Droplet-Associated Proteins in Plants Horn, Patrick J.; James, Christopher N.; Gidda, Satinder K. Plant Physiology, Vol. 162, Issue 4 https://doi.org/10.1104/pp.113.222455	journal	July 2013
Seed-Specific Over-Expression of an Arabidopsis cDNA Encoding a Diacylglycerol Acyltransferase Enhances Seed Oil Content and Seed Weight Jako, Colette; Kumar, Arvind; Wei, Yangdou Plant Physiology, Vol. 126, Issue 2 https://doi.org/10.1104/pp.126.2.861	journal	June 2001
Disruption of the Arabidopsis CGI-58 homologue produces Chanarin–Dorfman-like lipid droplet accumulation in plants James, Christopher N.; Horn, Patrick J.; Case, Charlene R. Proceedings of the National Academy of Sciences, Vol. 107, Issue 41, p. 17833-17838 https://doi.org/10.1073/pnas.0911359107	journal	September 2010
Two Activities of Long-Chain Acyl-Coenzyme A Synthetase Are Involved in Lipid Trafficking between the Endoplasmic Reticulum and the Plastid in Arabidopsis Jessen, Dirk; Roth, Charlotte; Wiermer, Marcel Plant Physiology, Vol. 167, Issue 2 https://doi.org/10.1104/pp.114.250365	journal	December 2014
The Arabidopsis stearoyl-acyl carrier protein-desaturase family and the contribution of leaf isoforms to oleic acid synthesis Kachroo, Aardra; Shanklin, John; Whittle, Edward Plant Molecular Biology, Vol. 63, Issue 2 https://doi.org/10.1007/s11103-006-9086-y	journal	October 2006
Diurnal Changes in Maize Leaf Photosynthesis: I. Carbon Exchange Rate, Assimilate Export Rate, and Enzyme Activities Kalt-Torres, Willy; Kerr, Phillip S.; Usuda, Hideaki Plant Physiology, Vol. 83, Issue 2 https://doi.org/10.1104/pp.83.2.283	journal	February 1987
Molecular Characterization of a Carbon Transporter in Plastids from Heterotrophic Tissues: The Glucose 6-Phosphate/Phosphate Antiporter Kammerer, Birgit; Fischer, Karsten; Hilpert, Bettina The Plant Cell, Vol. 10, Issue 1 https://doi.org/10.1105/tpc.10.1.105	journal	January 1998
Alteration of Seed Fatty Acid Composition by an Ethyl Methanesulfonate-Induced Mutation in Arabidopsis thaliana Affecting Diacylglycerol Acyltransferase Activity Katavic, V.; Reed, D. W.; Taylor, D. C. Plant Physiology, Vol. 108, Issue 1 https://doi.org/10.1104/pp.108.1.399	journal	May 1995
Coordinate Regulation of the Nuclear and Plastidic Genes Coding for the Subunits of the Heteromeric Acetyl-Coenzyme A Carboxylase Ke, Jinshan; Wen, Tuan-Nan; Nikolau, Basil J. Plant Physiology, Vol. 122, Issue 4 https://doi.org/10.1104/pp.122.4.1057	journal	April 2000
Seed Storage Oil Mobilization Is Important But Not Essential for Germination or Seedling Establishment in Arabidopsis Kelly, A. A.; Quettier, A.-L.; Shaw, E. PLANT PHYSIOLOGY, Vol. 157, Issue 2, p. 866-875 https://doi.org/10.1104/pp.111.181784	journal	October 2011
Suppression of the SUGAR-DEPENDENT1 triacylglycerol lipase family during seed development enhances oil yield in oilseed rape ( Brassica napus L.) Kelly, Amélie A.; Shaw, Eve; Powers, Stephen J. Plant Biotechnology Journal, Vol. 11, Issue 3 https://doi.org/10.1111/pbi.12021	journal	November 2012
The SUGAR-DEPENDENT1 Lipase Limits Triacylglycerol Accumulation in Vegetative Tissues of Arabidopsis Kelly, A. A.; van Erp, H.; Quettier, A.-L. PLANT PHYSIOLOGY, Vol. 162, Issue 3, p. 1282-1289 https://doi.org/10.1104/pp.113.219840	journal	May 2013
AtDSEL, an Arabidopsis cytosolic DAD1-like acylhydrolase, is involved in negative regulation of storage oil mobilization during seedling establishment Kim, Eun Yu; Seo, Young Sam; Kim, Woo Taek Journal of Plant Physiology, Vol. 168, Issue 14 https://doi.org/10.1016/j.jplph.2011.03.004	journal	September 2011
Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues Kim, Hyun Uk; Jung, Su-Jin; Lee, Kyeong-Ryeol FEBS Open Bio, Vol. 4, Issue 1 https://doi.org/10.1016/j.fob.2013.11.003	journal	November 2013
Senescence-inducible LEC2 enhances triacylglycerol accumulation in leaves without negatively affecting plant growth Kim, Hyun Uk; Lee, Kyeong-Ryeol; Jung, Su-Jin Plant Biotechnology Journal, Vol. 13, Issue 9 https://doi.org/10.1111/pbi.12354	journal	March 2015
A Stress-Responsive Caleosin-Like Protein, AtCLO4, Acts as a Negative Regulator of ABA Responses in Arabidopsis Kim, Yun Young; Jung, Kwang Wook; Yoo, Kyoung Shin Plant and Cell Physiology, Vol. 52, Issue 5 https://doi.org/10.1093/pcp/pcr039	journal	April 2011
Acyl-CoA dependent acylation of phospholipids in the chloroplast envelope Kjellberg, J. Magnus; Trimborn, Marc; Andersson, Mats Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1485, Issue 2-3 https://doi.org/10.1016/S1388-1981(00)00040-8	journal	May 2000
Lipid Droplets and Peroxisomes: Key Players in Cellular Lipid Homeostasis or A Matter of Fat--Store 'em Up or Burn 'em Down Kohlwein, S. D.; Veenhuis, M.; van der Klei, I. J. Genetics, Vol. 193, Issue 1, p. 1-50 https://doi.org/10.1534/genetics.112.143362	journal	December 2012
Carbon partitioning in A rabidopsis thaliana is a dynamic process controlled by the plants metabolic status and its circadian clock : Dynamic carbon partitioning in Kölling, Katharina; Thalmann, Matthias; Müller, Antonia Plant, Cell & Environment, Vol. 38, Issue 10 https://doi.org/10.1111/pce.12512	journal	April 2015
Identification of a plastid acyl-acyl carrier protein synthetase in Arabidopsis and its role in the activation and elongation of exogenous fatty acids Koo, Abraham J. K.; Fulda, Martin; Browse, John The Plant Journal, Vol. 44, Issue 4, p. 620-632 https://doi.org/10.1111/j.1365-313X.2005.02553.x	journal	October 2005
The ABC Transporter PXA1 and Peroxisomal -Oxidation Are Vital for Metabolism in Mature Leaves of Arabidopsis during Extended Darkness Kunz, H.-H.; Scharnewski, M.; Feussner, K. The Plant Cell Online, Vol. 21, Issue 9, p. 2733-2749 https://doi.org/10.1105/tpc.108.064857	journal	September 2009
Plant Acyl-CoA:Lysophosphatidylcholine Acyltransferases (LPCATs) Have Different Specificities in Their Forward and Reverse Reactions Lager, Ida; Yilmaz, Jenny Lindberg; Zhou, Xue-Rong Journal of Biological Chemistry, Vol. 288, Issue 52 https://doi.org/10.1074/jbc.M113.521815	journal	November 2013
Glyoxisome-like microbodies in senescent spinach leaves Landolt, Reto; Matile, Philippe Plant Science, Vol. 72, Issue 2 https://doi.org/10.1016/0168-9452(90)90078-3	journal	January 1990
Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome Lass, Achim; Zimmermann, Robert; Haemmerle, Guenter Cell Metabolism, Vol. 3, Issue 5 https://doi.org/10.1016/j.cmet.2006.03.005	journal	May 2006
Oil bodies in leaf mesophyll cells of angiosperms: overview and a selected survey Lersten, N. R.; Czlapinski, A. R.; Curtis, J. D. American Journal of Botany, Vol. 93, Issue 12 https://doi.org/10.3732/ajb.93.12.1731	journal	December 2006
A Putative Hydroxysteroid Dehydrogenase Involved in Regulating Plant Growth and Development Li, Fengling; Asami, Tadao; Wu, Xianzhong Plant Physiology, Vol. 145, Issue 1 https://doi.org/10.1104/pp.107.100560	journal	July 2007
CUE1: A Mesophyll Cell-Specific Positive Regulator of Light-Controlled Gene Expression in Arabidopsis. Li, Hm.; Culligan, K.; Dixon, R. A. The Plant Cell https://doi.org/10.1105/tpc.7.10.1599	journal	October 1995
FAX1, a Novel Membrane Protein Mediating Plastid Fatty Acid Export Li, Nannan; Gügel, Irene Luise; Giavalisco, Patrick PLOS Biology, Vol. 13, Issue 2 https://doi.org/10.1371/journal.pbio.1002053	journal	February 2015
DGAT1, DGAT2 and PDAT Expression in Seeds and Other Tissues of Epoxy and Hydroxy Fatty Acid Accumulating Plants Li, Runzhi; Yu, Keshun; Hildebrand, David F. Lipids, Vol. 45, Issue 2 https://doi.org/10.1007/s11745-010-3385-4	journal	January 2010
Oil content of Arabidopsis seeds: The influence of seed anatomy, light and plant-to-plant variation Li, Yonghua; Beisson, Fred; Pollard, Mike Phytochemistry, Vol. 67, Issue 9 https://doi.org/10.1016/j.phytochem.2006.02.015	journal	May 2006
Peroxisomal ATP Import Is Essential for Seedling Development in Arabidopsis thaliana Linka, Nicole; Theodoulou, Frederica L.; Haslam, Richard P. The Plant Cell, Vol. 20, Issue 12 https://doi.org/10.1105/tpc.108.062042	journal	December 2008
Fatty Acid Phytyl Ester Synthesis in Chloroplasts of Arabidopsis Lippold, Felix; vom Dorp, Katharina; Abraham, Marion The Plant Cell, Vol. 24, Issue 5 https://doi.org/10.1105/tpc.112.095588	journal	May 2012
Acyl-CoA:diacylglycerol acyltransferase: Molecular biology, biochemistry and biotechnology Liu, Qin; Siloto, Rodrigo M. P.; Lehner, Richard Progress in Lipid Research, Vol. 51, Issue 4 https://doi.org/10.1016/j.plipres.2012.06.001	journal	October 2012
Fatty acid production in genetically modified cyanobacteria Liu, X.; Sheng, J.; Curtiss III, R. Proceedings of the National Academy of Sciences, Vol. 108, Issue 17, p. 6899-6904 https://doi.org/10.1073/pnas.1103014108	journal	April 2011
Antisense suppression of type 1 diacylglycerol acyltransferase adversely affects plant development inBrassica napus Lock, Yee-Ying; Snyder, Crystal L.; Zhu, Weiming Physiologia Plantarum, Vol. 137, Issue 1 https://doi.org/10.1111/j.1399-3054.2009.01258.x	journal	September 2009
Analysis of Metabolic Flux Phenotypes for Two Arabidopsis Mutants with Severe Impairment in Seed Storage Lipid Synthesis Lonien, Joachim; Schwender, Jörg Plant Physiology, Vol. 151, Issue 3 https://doi.org/10.1104/pp.109.144121	journal	September 2009
Expression pattern of diacylglycerol acyltransferase-1, an enzyme involved in triacylglycerol biosynthesis, in Arabidopsis thaliana Lu, Chaofu Lu Plant Molecular Biology, Vol. 52, Issue 1, p. 31-41 https://doi.org/10.1023/A:1023935605864	journal	May 2003
Arabidopsis CER8 encodes LONG-CHAIN ACYL-COA SYNTHETASE 1 (LACS1) that has overlapping functions with LACS2 in plant wax and cutin synthesis Lü, Shiyou; Song, Tao; Kosma, Dylan K. The Plant Journal, Vol. 59, Issue 4 https://doi.org/10.1111/j.1365-313X.2009.03892.x	journal	August 2009
Deletion of a C-terminal intrinsically disordered region of WRINKLED1 affects its stability and enhances oil accumulation in Arabidopsis Ma, Wei; Kong, Que; Grix, Michael The Plant Journal, Vol. 83, Issue 5 https://doi.org/10.1111/tpj.12933	journal	August 2015
An AP2-type transcription factor, WRINKLED1, of Arabidopsis thaliana binds to the AW-box sequence conserved among proximal upstream regions of genes involved in fatty acid synthesis Maeo, Kenichiro; Tokuda, Tsuyoshi; Ayame, Atsuko The Plant Journal, Vol. 60, Issue 3 https://doi.org/10.1111/j.1365-313X.2009.03967.x	journal	November 2009
Lipid droplets: a unified view of a dynamic organelle Martin, Sally; Parton, Robert G. Nature Reviews Molecular Cell Biology, Vol. 7, Issue 5 https://doi.org/10.1038/nrm1912	journal	March 2006
ACTIVATOR of Spomin::LUC1/WRINKLED1 of Arabidopsis thaliana Transactivates Sugar-inducible Promoters Masaki, Takeshi; Mitsui, Naoko; Tsukagoshi, Hironaka Plant and Cell Physiology, Vol. 46, Issue 4 https://doi.org/10.1093/pcp/pci072	journal	April 2005
Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation Mitra, M. S.; Chen, Z.; Ren, H. Proceedings of the National Academy of Sciences, Vol. 110, Issue 2 https://doi.org/10.1073/pnas.1213493110	journal	December 2012
Control limits for accumulation of plant metabolites: brute force is no substitute for understanding Morandini, Piero Plant Biotechnology Journal, Vol. 11, Issue 2 https://doi.org/10.1111/pbi.12035	journal	January 2013
The biogenesis and functions of lipid bodies in animals, plants and microorganisms Murphy, D. Progress in Lipid Research, Vol. 40, Issue 5 https://doi.org/10.1016/S0163-7827(01)00013-3	journal	September 2001
Arabidopsis lipins mediate eukaryotic pathway of lipid metabolism and cope critically with phosphate starvation Nakamura, Y.; Koizumi, R.; Shui, G. Proceedings of the National Academy of Sciences, Vol. 106, Issue 49, p. 20978-20983 https://doi.org/10.1073/pnas.0907173106	journal	November 2009
The Production of Unusual Fatty Acids in Transgenic Plants Napier, Johnathan A. Annual Review of Plant Biology, Vol. 58, Issue 1 https://doi.org/10.1146/annurev.arplant.58.032806.103811	journal	June 2007
Understanding and manipulating plant lipid composition: Metabolic engineering leads the way Napier, Johnathan A.; Haslam, Richard P.; Beaudoin, Frederic Current Opinion in Plant Biology, Vol. 19 https://doi.org/10.1016/j.pbi.2014.04.001	journal	June 2014
The Arabidopsis Plastidic Glucose 6-Phosphate/Phosphate Translocator GPT1 Is Essential for Pollen Maturation and Embryo Sac Development Niewiadomski, Patrycja; Knappe, Silke; Geimer, Stefan The Plant Cell, Vol. 17, Issue 3 https://doi.org/10.1105/tpc.104.029124	journal	February 2005
Metabolic cartography: experimental quantification of metabolic fluxes from isotopic labelling studies O'Grady, J.; Schwender, J.; Shachar-Hill, Y. Journal of Experimental Botany, Vol. 63, Issue 6 https://doi.org/10.1093/jxb/ers032	journal	February 2012
PICKLE is a CHD3 chromatin-remodeling factor that regulates the transition from embryonic to vegetative development in Arabidopsis Ogas, J.; Kaufmann, S.; Henderson, J. Proceedings of the National Academy of Sciences, Vol. 96, Issue 24 https://doi.org/10.1073/pnas.96.24.13839	journal	November 1999
Driving on Biomass Ohlrogge, J.; Allen, D.; Berguson, B. Science, Vol. 324, Issue 5930 https://doi.org/10.1126/science.1171740	journal	May 2009
Lipid Biosynthesis Ohlrogge, J.; Browse, J. THE PLANT CELL ONLINE, Vol. 7, Issue 7, p. 957-970 https://doi.org/10.1105/tpc.7.7.957	journal	July 1995
Regulation of Fatty Acid Synthesis Ohlrogge, John B.; Jaworski, Jan G. Annual Review of Plant Physiology and Plant Molecular Biology, Vol. 48, Issue 1, p. 109-136 https://doi.org/10.1146/annurev.arplant.48.1.109	journal	June 1997
Lipid droplets as dynamic organelles connecting storage and efflux of lipids Olofsson, Sven-Olof; Boström, Pontus; Andersson, Linda Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1791, Issue 6 https://doi.org/10.1016/j.bbalip.2008.08.001	journal	June 2009
Characterization of a Plastid Triacylglycerol Lipase from Arabidopsis Padham, Anita K.; Hopkins, Marianne T.; Wang, Tzann-Wei Plant Physiology, Vol. 143, Issue 3 https://doi.org/10.1104/pp.106.090811	journal	January 2007
The α/β Hydrolase CGI-58 and Peroxisomal Transport Protein PXA1 Coregulate Lipid Homeostasis and Signaling in Arabidopsis Park, Sunjung; Gidda, Satinder K.; James, Christopher N. The Plant Cell, Vol. 25, Issue 5, p. 1726-1739 https://doi.org/10.1105/tpc.113.111898	journal	May 2013
Phosphatidate phosphatase, a key regulator of lipid homeostasis Pascual, Florencia; Carman, George M. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1831, Issue 3 https://doi.org/10.1016/j.bbalip.2012.08.006	journal	March 2013
Recruiting a New Substrate for Triacylglycerol Synthesis in Plants: The Monoacylglycerol Acyltransferase Pathway Petrie, James R.; Vanhercke, Thomas; Shrestha, Pushkar PLoS ONE, Vol. 7, Issue 4 https://doi.org/10.1371/journal.pone.0035214	journal	April 2012
Phosphoenolpyruvate Provision to Plastids Is Essential for Gametophyte and Sporophyte Development in Arabidopsis thaliana Prabhakar, Veena; Löttgert, Tanja; Geimer, Stefan The Plant Cell, Vol. 22, Issue 8 https://doi.org/10.1105/tpc.109.073171	journal	August 2010
Molecular and functional characterization of the plastid-localized Phosphoenolpyruvate enolase (ENO1) from Arabidopsis thaliana Prabhakar, Veena; Löttgert, Tanja; Gigolashvili, Tamara FEBS Letters, Vol. 583, Issue 6 https://doi.org/10.1016/j.febslet.2009.02.017	journal	February 2009
Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics Rambold, Angelika S.; Cohen, Sarah; Lippincott-Schwartz, Jennifer Developmental Cell, Vol. 32, Issue 6 https://doi.org/10.1016/j.devcel.2015.01.029	journal	March 2015
Metabolic engineering of medium-chain fatty acid biosynthesis in Nicotiana benthamiana plant leaf lipids Reynolds, Kyle B.; Taylor, Matthew C.; Zhou, Xue-Rong Frontiers in Plant Science, Vol. 6 https://doi.org/10.3389/fpls.2015.00164	journal	March 2015
Targeting of the Arabidopsis Homomeric Acetyl-Coenzyme A Carboxylase to Plastids of Rapeseeds Roesler, K.; Shintani, D.; Savage, L. Plant Physiology, Vol. 113, Issue 1, p. 75-81 https://doi.org/10.1104/pp.113.1.75	journal	January 1997
Sugar sensing and signalling networks in plants Rolland, F.; Sheen, J. Biochemical Society Transactions, Vol. 33, Issue 1 https://doi.org/10.1042/BST0330269	journal	February 2005
Reconstitution of EPA and DHA biosynthesis in Arabidopsis: Iterative metabolic engineering for the synthesis of n−3 LC-PUFAs in transgenic plants Ruiz-Lopez, Noemi; Haslam, Richard P.; Usher, Sarah L. Metabolic Engineering, Vol. 17 https://doi.org/10.1016/j.ymben.2013.03.001	journal	May 2013
Contrapuntal Networks of Gene Expression during Arabidopsis Seed Filling Ruuska, Sari A.; Girke, Thomas; Benning, Christoph The Plant Cell, Vol. 14, Issue 6 https://doi.org/10.1105/tpc.000877	journal	June 2002
Increasing the energy density of vegetative tissues by diverting carbon from starch to oil biosynthesis in transgenic Arabidopsis Plant Biotechnology Journal, Vol. 9, Issue 8, p. 874-883 https://doi.org/10.1111/j.1467-7652.2011.00599.x	journal	February 2011
Altered Lipid Composition and Enhanced Nutritional Value of Arabidopsis Leaves following Introduction of an Algal Diacylglycerol Acyltransferase 2 The Plant Cell, Vol. 25, Issue 2 https://doi.org/10.1105/tpc.112.104752	journal	February 2013
Deciphering gene regulatory networks that control seed development and maturation in Arabidopsis Santos-Mendoza, Monica; Dubreucq, Bertrand; Baud, Sébastien The Plant Journal, Vol. 54, Issue 4 https://doi.org/10.1111/j.1365-313X.2008.03461.x	journal	May 2008
LEAFY COTYLEDON 2 activation is sufficient to trigger the accumulation of oil and seed specific mRNAs in Arabidopsis leaves Santos Mendoza, Monica; Dubreucq, Bertrand; Miquel, Martine FEBS Letters, Vol. 579, Issue 21 https://doi.org/10.1016/j.febslet.2005.07.037	journal	August 2005
The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth Santos-Rosa, Helena; Leung, Joanne; Grimsey, Neil The EMBO Journal, Vol. 24, Issue 11, p. 1931-1941 https://doi.org/10.1038/sj.emboj.7600672	journal	May 2005
Link between light and fatty acid synthesis: Thioredoxin-linked reductive activation of plastidic acetyl-CoA carboxylase Sasaki, Y.; Kozaki, A.; Hatano, M. Proceedings of the National Academy of Sciences, Vol. 94, Issue 20 https://doi.org/10.1073/pnas.94.20.11096	journal	September 1997
The Acyl-CoA Synthetase Encoded by LACS2 Is Essential for Normal Cuticle Development in Arabidopsis Schnurr, Judy; Shockey, Jay; Browse, John The Plant Cell, Vol. 16, Issue 3 https://doi.org/10.1105/tpc.017608	journal	February 2004
Predictive Modeling of Biomass Component Tradeoffs in Brassica napus Developing Oilseeds Based on in Silico Manipulation of Storage Metabolism Schwender, Jörg; Hay, Jordan O. Plant Physiology, Vol. 160, Issue 3 https://doi.org/10.1104/pp.112.203927	journal	September 2012
Quantitative Multilevel Analysis of Central Metabolism in Developing Oilseeds of Oilseed Rape during in Vitro Culture Schwender, Jörg; Hebbelmann, Inga; Heinzel, Nicolas Plant Physiology, Vol. 168, Issue 3 https://doi.org/10.1104/pp.15.00385	journal	May 2015
Elevation of oil body integrity and emulsion stability by polyoleosins, multiple oleosin units joined in tandem head-to-tail fusions: Polyoleosin elevates oil body stability Scott, Richard W.; Winichayakul, Somrutai; Roldan, Marissa Plant Biotechnology Journal, Vol. 8, Issue 8 https://doi.org/10.1111/j.1467-7652.2010.00522.x	journal	September 2010
Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1 Shi, Shuobo; Chen, Yun; Siewers, Verena mBio, Vol. 5, Issue 3 https://doi.org/10.1128/mBio.01130-14	journal	May 2014
Oil-Body-Membrane Proteins and Their Physiological Functions in Plants Shimada, Takashi L.; Hara-Nishimura, Ikuko Biological & Pharmaceutical Bulletin, Vol. 33, Issue 3 https://doi.org/10.1248/bpb.33.360	journal	January 2010
A novel role for oleosins in freezing tolerance of oilseeds in Arabidopsis thaliana Shimada, Takashi L.; Shimada, Tomoo; Takahashi, Hideyuki The Plant Journal, Vol. 55, Issue 5 https://doi.org/10.1111/j.1365-313X.2008.03553.x	journal	September 2008
Leaf Oil Body Functions as a Subcellular Factory for the Production of a Phytoalexin in Arabidopsis Shimada, T. L.; Takano, Y.; Shimada, T. PLANT PHYSIOLOGY, Vol. 164, Issue 1 https://doi.org/10.1104/pp.113.230185	journal	November 2013
Feedback inhibition of fatty acid synthesis in tobacco suspension cells Shintani, David K.; Ohlrogge, John B. The Plant Journal, Vol. 7, Issue 4 https://doi.org/10.1046/j.1365-313X.1995.7040577.x	journal	April 1995
Arabidopsis Contains Nine Long-Chain Acyl-Coenzyme A Synthetase Genes That Participate in Fatty Acid and Glycerolipid Metabolism Shockey, Jay M.; Fulda, Martin S.; Browse, John A. Plant Physiology, Vol. 129, Issue 4 https://doi.org/10.1104/pp.003269	journal	July 2002
The Accumulation of Oleosins Determines the Size of Seed Oilbodies in Arabidopsis Siloto, Rodrigo M. P.; Findlay, Kim; Lopez-Villalobos, Arturo The Plant Cell, Vol. 18, Issue 8 https://doi.org/10.1105/tpc.106.041269	journal	July 2006
Autophagy regulates lipid metabolism Singh, Rajat; Kaushik, Susmita; Wang, Yongjun Nature, Vol. 458, Issue 7242 https://doi.org/10.1038/nature07976	journal	April 2009
Oil accumulation in leaves directed by modification of fatty acid breakdown and lipid synthesis pathways Slocombe, Steve P.; Cornah, Jo; Pinfield-Wells, Helen Plant Biotechnology Journal, Vol. 7, Issue 7, p. 694-703 https://doi.org/10.1111/j.1467-7652.2009.00435.x	journal	September 2009
Mitochondria and Spherosomes in the Living Epidermal Cell Sorokin, Helen P. American Journal of Botany, Vol. 42, Issue 3, p. 225 https://doi.org/10.2307/2438558	journal	March 1955
Cloning and Functional Characterization of a Phospholipid:Diacylglycerol Acyltransferase from Arabidopsis Ståhl, Ulf; Carlsson, Anders S.; Lenman, Marit Plant Physiology, Vol. 135, Issue 3 https://doi.org/10.1104/pp.104.044354	journal	July 2004
Starch turnover: pathways, regulation and role in growth Stitt, Mark; Zeeman, Samuel C. Current Opinion in Plant Biology, Vol. 15, Issue 3 https://doi.org/10.1016/j.pbi.2012.03.016	journal	June 2012
LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development Stone, S. L.; Kwong, L. W.; Yee, K. M. Proceedings of the National Academy of Sciences, Vol. 98, Issue 20 https://doi.org/10.1073/pnas.201413498	journal	September 2001
Peroxisome extensions deliver the Arabidopsis SDP1 lipase to oil bodies Thazar-Poulot, Nelcy; Miquel, Martine; Fobis-Loisy, Isabelle Proceedings of the National Academy of Sciences, Vol. 112, Issue 13 https://doi.org/10.1073/pnas.1403322112	journal	March 2015
Both antisense and sense expression of biotin carboxyl carrier protein isoform 2 inactivates the plastid acetyl-coenzyme A carboxylase in Arabidopsis thaliana Thelen, Jay J.; Ohlrogge, John B. The Plant Journal, Vol. 32, Issue 4 https://doi.org/10.1046/j.1365-313X.2002.01435.x	journal	November 2002
Seed storage oil catabolism: a story of give and take Theodoulou, Frederica L.; Eastmond, Peter J. Current Opinion in Plant Biology, Vol. 15, Issue 3, p. 322-328 https://doi.org/10.1016/j.pbi.2012.03.017	journal	June 2012
Peroxisomal ABC transporters Theodoulou, Frederica L.; Holdsworth, Michael; Baker, Alison FEBS Letters, Vol. 580, Issue 4 https://doi.org/10.1016/j.febslet.2005.12.095	journal	January 2006
Tracking synthesis and turnover of triacylglycerol in leaves Tjellström, Henrik; Strawsine, Merissa; Ohlrogge, John B. Journal of Experimental Botany, Vol. 66, Issue 5 https://doi.org/10.1093/jxb/eru500	journal	January 2015
Disruption of plastid acyl:acyl carrier protein synthetases increases medium chain fatty acid accumulation in seeds of transgenic Arabidopsis Tjellström, Henrik; Strawsine, Merissa; Silva, Jillian FEBS Letters, Vol. 587, Issue 7 https://doi.org/10.1016/j.febslet.2013.02.021	journal	February 2013
Rapid Kinetic Labeling of Arabidopsis Cell Suspension Cultures: Implications for Models of Lipid Export from Plastids Tjellström, Henrik; Yang, Zhenle; Allen, Doug K. Plant Physiology, Vol. 158, Issue 2 https://doi.org/10.1104/pp.111.186122	journal	November 2011
WRINKLED Transcription Factors Orchestrate Tissue-Specific Regulation of Fatty Acid Biosynthesis in Arabidopsis To, Alexandra; Joubès, Jérôme; Barthole, Guillaume The Plant Cell, Vol. 24, Issue 12 https://doi.org/10.1105/tpc.112.106120	journal	December 2012
Lipid turnover during senescence Troncoso-Ponce, Manuel A.; Cao, Xia; Yang, Zhenle Plant Science, Vol. 205-206, p. 13-19 https://doi.org/10.1016/j.plantsci.2013.01.004	journal	May 2013
New insights on the organization and regulation of the fatty acid biosynthetic network in the model higher plant Arabidopsis thaliana Troncoso-Ponce, Manuel Adrián; Nikovics, Krisztina; Marchive, Chloé Biochimie, Vol. 120 https://doi.org/10.1016/j.biochi.2015.05.013	journal	January 2016
Lipin Is a Central Regulator of Adipose Tissue Development and Function in Drosophila melanogaster Ugrankar, Rupali; Liu, Yanling; Provaznik, Jill Molecular and Cellular Biology, Vol. 31, Issue 8 https://doi.org/10.1128/MCB.01335-10	journal	April 2011
Lipin-2 Reduces Proinflammatory Signaling Induced by Saturated Fatty Acids in Macrophages Valdearcos, Martín; Esquinas, Esperanza; Meana, Clara Journal of Biological Chemistry, Vol. 287, Issue 14 https://doi.org/10.1074/jbc.M112.342915	journal	March 2012
Transcription Analysis of Arabidopsis Membrane Transporters and Hormone Pathways during Developmental and Induced Leaf Senescence van der Graaff, Eric; Schwacke, Rainer; Schneider, Anja Plant Physiology, Vol. 141, Issue 2 https://doi.org/10.1104/pp.106.079293	journal	April 2006
Metabolic engineering of biomass for high energy density: oilseed-like triacylglycerol yields from plant leaves Vanhercke, Thomas; El Tahchy, Anna; Liu, Qing Plant Biotechnology Journal, Vol. 12, Issue 2 https://doi.org/10.1111/pbi.12131	journal	October 2013
Synergistic effect of WRI1 and DGAT1 coexpression on triacylglycerol biosynthesis in plants Vanhercke, Thomas; El Tahchy, Anna; Shrestha, Pushkar FEBS Letters, Vol. 587, Issue 4 https://doi.org/10.1016/j.febslet.2012.12.018	journal	January 2013
Energy densification in vegetative biomass through metabolic engineering Vanhercke, Thomas; Petrie, James R.; Singh, Surinder P. Biocatalysis and Agricultural Biotechnology, Vol. 3, Issue 1 https://doi.org/10.1016/j.bcab.2013.11.010	journal	January 2014
Plant Acyl-ACP Thioesterases: Chain-Length Determining Enzymes in Plant Fatty Acid Biosynthesis Voelker, Toni Genetic Engineering https://doi.org/10.1007/978-1-4899-1766-9_8	book	January 1996
Oleosin expression and trafficking during oil body biogenesis in tobacco leaf cells Wahlroos, Tony; Soukka, Jori; Denesyuk, Alexander genesis, Vol. 35, Issue 2 https://doi.org/10.1002/gene.10172	journal	January 2003
Metabolic Interactions between the Lands Cycle and the Kennedy Pathway of Glycerolipid Synthesis in Arabidopsis Developing Seeds Wang, Liping; Shen, Wenyun; Kazachkov, Michael The Plant Cell, Vol. 24, Issue 11 https://doi.org/10.1105/tpc.112.104604	journal	November 2012
Chloroplast lipid synthesis and lipid trafficking through ER–plastid membrane contact sites Wang, Zhen; Benning, Christoph Biochemical Society Transactions, Vol. 40, Issue 2 https://doi.org/10.1042/BST20110752	journal	March 2012
Connecting the Plastid: Transporters of the Plastid Envelope and Their Role in Linking Plastidial with Cytosolic Metabolism Weber, Andreas P. M.; Linka, Nicole Annual Review of Plant Biology, Vol. 62, Issue 1 https://doi.org/10.1146/annurev-arplant-042110-103903	journal	June 2011
Lipid droplet biogenesis Wilfling, Florian; Haas, Joel T.; Walther, Tobias C. Current Opinion in Cell Biology, Vol. 29 https://doi.org/10.1016/j.ceb.2014.03.008	journal	August 2014
In Vivo Packaging of Triacylglycerols Enhances Arabidopsis Leaf Biomass and Energy Density Winichayakul, Somrutai; Scott, Richard William; Roldan, Marissa Plant Physiology, Vol. 162, Issue 2 https://doi.org/10.1104/pp.113.216820	journal	April 2013
Effects of Monogalactoglycerolipid Deficiency and Diacylglycerol Acyltransferase Overexpression on Oil Accumulation in Transgenic Tobacco Wu, Han-Ying; Liu, Chao; Li, Min-Chun Plant Molecular Biology Reporter, Vol. 31, Issue 5 https://doi.org/10.1007/s11105-013-0574-3	journal	March 2013
Mutation of the TGD1 Chloroplast Envelope Protein Affects Phosphatidate Metabolism in Arabidopsis Xu, Changcheng; Fan, Jilian; Froehlich, John E. The Plant Cell, Vol. 17, Issue 11, p. 3094-3110 https://doi.org/10.1105/tpc.105.035592	journal	November 2005
Chanarin–Dorfman syndrome: Deficiency in CGI-58, a lipid droplet-bound coactivator of lipase Yamaguchi, Tomohiro; Osumi, Takashi Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1791, Issue 6 https://doi.org/10.1016/j.bbalip.2008.10.012	journal	June 2009
MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice Yang, Chao; Ma, Biao; He, Si-Jie Plant Physiology, Vol. 169, Issue 1 https://doi.org/10.1104/pp.15.00353	journal	May 2015
Turnover of Fatty Acids during Natural Senescence of Arabidopsis, Brachypodium , and Switchgrass and in Arabidopsis β- Oxidation Mutants Yang, Zhenle; Ohlrogge, John B. Plant Physiology, Vol. 150, Issue 4 https://doi.org/10.1104/pp.109.140491	journal	June 2009
Circadian control of root elongation and C partitioning in Arabidopsis thaliana : Circadian control of root growth Yazdanbakhsh, Nima; Sulpice, Ronan; Graf, Alexander Plant, Cell & Environment, Vol. 34, Issue 6 https://doi.org/10.1111/j.1365-3040.2011.02286.x	journal	March 2011
Metabolic engineering of sugarcane to accumulate energy-dense triacylglycerols in vegetative biomass Zale, Janice; Jung, Je Hyeong; Kim, Jae Yoon Plant Biotechnology Journal, Vol. 14, Issue 2 https://doi.org/10.1111/pbi.12411	journal	June 2015
DGAT1 and PDAT1 Acyltransferases Have Overlapping Functions in Arabidopsis Triacylglycerol Biosynthesis and Are Essential for Normal Pollen and Seed Development Zhang, Meng; Fan, Jilian; Taylor, David C. The Plant Cell, Vol. 21, Issue 12 https://doi.org/10.1105/tpc.109.071795	journal	December 2009
Lipin-1 Phosphatidic Phosphatase Activity Modulates Phosphatidate Levels to Promote Peroxisome Proliferator-activated Receptor γ (PPARγ) Gene Expression during Adipogenesis Zhang, Peixiang; Takeuchi, Kazuharu; Csaki, Lauren S. Journal of Biological Chemistry, Vol. 287, Issue 5 https://doi.org/10.1074/jbc.M111.296681	journal	January 2012
Insertional mutant analysis reveals that long-chain acyl-CoA synthetase 1 (LACS1), but not LACS8, functionally overlaps with LACS9 in Arabidopsis seed oil biosynthesis: Overlapping functions of LACS1 and LACS9 in TAG biosynthesis Zhao, Lifang; Katavic, Vesna; Li, Fengling The Plant Journal, Vol. 64, Issue 6 https://doi.org/10.1111/j.1365-313X.2010.04396.x	journal	November 2010
Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase Zimmermann, R. Science, Vol. 306, Issue 5700 https://doi.org/10.1126/science.1100747	journal	November 2004
The Arabidopsis pxa1 Mutant Is Defective in an ATP-Binding Cassette Transporter-Like Protein Required for Peroxisomal Fatty Acid β-Oxidation Zolman, Bethany K.; Silva, Illeana D.; Bartel, Bonnie Plant Physiology, Vol. 127, Issue 3 https://doi.org/10.1104/pp.010550	journal	November 2001

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Oil body biogenesis and biotechnology in legume seeds Song, Youhong; Wang, Xin-Ding; Rose, Ray J. Plant Cell Reports, Vol. 36, Issue 10 https://doi.org/10.1007/s00299-017-2201-5	journal	September 2017
Isolation and characterization of the EgWRI1 promoter from oil palm (Elaeis guineensis Jacq.) and its response to environmental stress and ethylene Zhang, Qing; Sun, Ruhao; Zheng, Yusheng PLOS ONE, Vol. 14, Issue 12 https://doi.org/10.1371/journal.pone.0225115	journal	December 2019
Molecular and biochemical analysis of the castor caruncle reveals a set of unique genes involved in oil accumulation in non-seed tissues Wan, Xia; Liu, Qing; Dong, Bei Biotechnology for Biofuels, Vol. 12, Issue 1 https://doi.org/10.1186/s13068-019-1496-6	journal	June 2019
Diversion of Carbon Flux from Sugars to Lipids Improves the Growth of an Arabidopsis Starchless Mutant Fan, Jilian; Zhou, Chao; Yu, Linhui Plants, Vol. 8, Issue 7 https://doi.org/10.3390/plants8070229	journal	July 2019
FUSCA3 activates triacylglycerol accumulation in Arabidopsis seedlings and tobacco BY2 cells Zhang, Meng; Cao, Xia; Jia, Qingli The Plant Journal, Vol. 88, Issue 1 https://doi.org/10.1111/tpj.13233	journal	August 2016
The multistress-induced Translocator protein (TSPO) differentially modulates storage lipids metabolism in seeds and seedlings Jurkiewicz, Pawel; Melser, Su; Maucourt, Mickaël The Plant Journal, Vol. 96, Issue 2 https://doi.org/10.1111/tpj.14028	journal	August 2018
Response of high leaf-oil Arabidopsis thaliana plant lines to biotic or abiotic stress Yurchenko, Olga; Kimberlin, Athen; Mehling, Marina Plant Signaling & Behavior, Vol. 13, Issue 5 https://doi.org/10.1080/15592324.2018.1464361	journal	May 2018
Metabolite Profiling and Classification of Developing Styrax tonkinensis Kernels Wu, Qikui; Zhao, Xue; Chen, Chen Metabolites, Vol. 10, Issue 1 https://doi.org/10.3390/metabo10010021	journal	January 2020
Selection and Validation of Reference Genes for qRT-PCR Analysis in the Oil-Rich Tuber Crop Tiger Nut (Cyperus esculentus) Based on Transcriptome Data Bai, Xue; Chen, Tao; Wu, Yuan International Journal of Molecular Sciences, Vol. 22, Issue 5 https://doi.org/10.3390/ijms22052569	journal	March 2021
An efficient and comprehensive plant glycerolipids analysis approach based on high‐performance liquid chromatography–quadrupole time‐of‐flight mass spectrometer Lu, Shaoping; Liu, Hongbo; Jin, Cheng Plant Direct, Vol. 3, Issue 11 https://doi.org/10.1002/pld3.183	journal	November 2019
Upregulated Lipid Biosynthesis at the Expense of Starch Production in Potato (Solanum tuberosum) Vegetative Tissues via Simultaneous Downregulation of ADP-Glucose Pyrophosphorylase and Sugar Dependent1 Expressions Xu, Xiaoyu; Vanhercke, Thomas; Shrestha, Pushkar Frontiers in Plant Science, Vol. 10 https://doi.org/10.3389/fpls.2019.01444	journal	November 2019
Involvement of Phosphatidylserine and Triacylglycerol in the Response of Sweet Potato Leaves to Salt Stress Yu, Yicheng; Kou, Meng; Gao, Zhonghui Frontiers in Plant Science, Vol. 10 https://doi.org/10.3389/fpls.2019.01086	journal	September 2019
Genome-wide characterization and expression profiling of diacylglycerol acyltransferase genes from maize Yan, Bowei; Xu, Xiaoxuan; Gu, Yingnan Genome, Vol. 61, Issue 10 https://doi.org/10.1139/gen-2018-0029	journal	October 2018
Characterization and Functional Analysis of a Type 2 Diacylglycerol Acyltransferase (DGAT2) Gene from Oil Palm (Elaeis guineensis Jacq.) Mesocarp in Saccharomyces cerevisiae and Transgenic Arabidopsis thaliana Jin, Yuanhang; Yuan, Yijun; Gao, Lingchao Frontiers in Plant Science, Vol. 8 https://doi.org/10.3389/fpls.2017.01791	journal	October 2017
Biomass and lipid induction strategies in microalgae for biofuel production and other applications Alishah Aratboni, Hossein; Rafiei, Nahid; Garcia-Granados, Raul Microbial Cell Factories, Vol. 18, Issue 1 https://doi.org/10.1186/s12934-019-1228-4	journal	October 2019
Functional Characterization of Physcomitrella patens Glycerol-3-Phosphate Acyltransferase 9 and an Increase in Seed Oil Content in Arabidopsis by Its Ectopic Expression Plants, Vol. 8, Issue 8 https://doi.org/10.3390/plants8080284	journal	August 2019
Proteomic Analysis of Lipid Droplets from Arabidopsis Aging Leaves Brings New Insight into Their Biogenesis and Functions Brocard, Lysiane; Immel, Françoise; Coulon, Denis Frontiers in Plant Science, Vol. 8 https://doi.org/10.3389/fpls.2017.00894	journal	May 2017
Transcriptome analysis of metabolic pathways associated with oil accumulation in developing seed kernels of Styrax tonkinensis, a woody biodiesel species Wu, Qikui; Cao, Yuanyuan; Chen, Chen BioMed Central https://doi.org/10.14288/1.0389598	text	January 2020
Engineering biosynthesis of high-value compounds in photosynthetic organisms O’Neill, Ellis C.; Kelly, Steven Critical Reviews in Biotechnology, Vol. 37, Issue 6 https://doi.org/10.1080/07388551.2016.1237467	journal	October 2016
Engineering biosynthesis of high-value compounds in photosynthetic organisms O’Neill, Ellis C.; Kelly, Steven Taylor & Francis https://doi.org/10.6084/m9.figshare.3984426	text	January 2016
Mouse fat storage-inducing transmembrane protein 2 (FIT2) promotes lipid droplet accumulation in plants Cai, Yingqi; McClinchie, Elizabeth; Price, Ann Plant Biotechnology Journal, Vol. 15, Issue 7 https://doi.org/10.1111/pbi.12678	journal	January 2017
Transcriptome analysis of metabolic pathways associated with oil accumulation in developing seed kernels of Styrax tonkinensis, a woody biodiesel species Wu, Qikui; Cao, Yuanyuan; Chen, Chen BMC Plant Biology, Vol. 20, Issue 1 https://doi.org/10.1186/s12870-020-2327-4	journal	March 2020
Single cell-type analysis of cellular lipid remodelling in response to salinity in the epidermal bladder cells of the model halophyte Mesembryanthemum crystallinum: Cellular lipid remodelling under salt stress Barkla, Bronwyn J.; Garibay-Hernández, Adriana; Melzer, Michael Plant, Cell & Environment, Vol. 41, Issue 10 https://doi.org/10.1111/pce.13352	journal	July 2018
Engineering biosynthesis of high-value compounds in photosynthetic organisms O’Neill, Ellis C.; Kelly, Steven Taylor & Francis https://doi.org/10.6084/m9.figshare.3984426.v1	text	January 2016
Mouse lipogenic proteins promote the co-accumulation of triacylglycerols and sesquiterpenes in plant cells Cai, Yingqi; Whitehead, Payton; Chappell, Joe Planta, Vol. 250, Issue 1 https://doi.org/10.1007/s00425-019-03148-9	journal	March 2019
Engineering the production of conjugated fatty acids in Arabidopsis thaliana leaves Yurchenko, Olga; Shockey, Jay M.; Gidda, Satinder K. Plant Biotechnology Journal, Vol. 15, Issue 8 https://doi.org/10.1111/pbi.12695	journal	March 2017
Melatonin-Stimulated Triacylglycerol Breakdown and Energy Turnover under Salinity Stress Contributes to the Maintenance of Plasma Membrane H+–ATPase Activity and K+/Na+ Homeostasis in Sweet Potato Yu, Yicheng; Wang, Aimin; Li, Xiang Frontiers in Plant Science, Vol. 9 https://doi.org/10.3389/fpls.2018.00256	journal	February 2018
De novo Assembly and Characterization of the Fruit Transcriptome of Idesia polycarpa Reveals Candidate Genes for Lipid Biosynthesis Li, Rong-Jun; Gao, Xiang; Li, Lin-Mao Frontiers in Plant Science, Vol. 7 https://doi.org/10.3389/fpls.2016.00801	journal	June 2016

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