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Title: Assessment of microcrystal quality by transmission electron microscopy for efficient serial femtosecond crystallography

Journal Article · · Archives of Biochemistry and Biophysics

Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES); USDOE Office of Science (SC), Biological and Environmental Research (BER)
Grant/Contract Number:
0006-15; AC02-76SF00515
OSTI ID:
1324012
Journal Information:
Archives of Biochemistry and Biophysics, Journal Name: Archives of Biochemistry and Biophysics Vol. 602 Journal Issue: C; ISSN 0003-9861
Publisher:
ElsevierCopyright Statement
Country of Publication:
United States
Language:
English
Citation Metrics:
Cited by: 11 works
Citation information provided by
Web of Science

References (38)

Emerging opportunities in structural biology with X-ray free-electron lasers journal October 2012
Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams journal January 2015
Grease matrix as a versatile carrier of proteins for serial crystallography journal November 2014
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser journal July 2015
Toward structure determination using membrane–protein nanocrystals and microcrystals journal December 2011
Indexing amyloid peptide diffraction from serial femtosecond crystallography: new algorithms for sparse patterns journal January 2015
Time-resolved protein nanocrystallography using an X-ray free-electron laser journal January 2012
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography journal February 2014
Room temperature structures beyond 1.5 Å by serial femtosecond crystallography journal May 2015
High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography journal May 2012
Processing of X-ray snapshots from crystals in random orientations journal July 2014
An improved integration method in serial femtosecond crystallography journal April 2014
Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data journal March 2015
Femtosecond protein nanocrystallography—data analysis methods journal January 2010
Transmission electron microscopy as a tool for nanocrystal characterization pre- and post-injector journal July 2014
Femtosecond X-ray protein nanocrystallography journal February 2011
Autoindexing with outlier rejection and identification of superimposed lattices journal April 2010
Serial femtosecond crystallography: the first five years journal February 2015
Aromatic Ring Cleavage by Homoprotocatechuate 2,3-Dioxygenase:  Role of His200 in the Kinetics of Interconversion of Reaction Cycle Intermediates journal May 2005
High Throughput Protein Nanocrystal Fractionation in a Microfluidic Sorter journal April 2015
Improved crystal orientation and physical properties from single-shot XFEL stills journal November 2014
Serial femtosecond crystallography of soluble proteins in lipidic cubic phase journal August 2015
A novel inert crystal delivery medium for serial femtosecond crystallography journal June 2015
Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein journal December 2014
Use of transmission electron microscopy to identify nanocrystals of challenging protein targets journal May 2014
Structural Basis for the Role of Tyrosine 257 of Homoprotocatechuate 2,3-Dioxygenase in Substrate and Oxygen Activation journal October 2012
Microcrystallization techniques for serial femtosecond crystallography using photosystem II from Thermosynechococcus elongatus as a model system
  • Kupitz, Christopher; Grotjohann, Ingo; Conrad, Chelsie E.
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 369, Issue 1647 https://doi.org/10.1098/rstb.2013.0316
journal July 2014
Reliably distinguishing protein nanocrystals from amorphous precipitate by means of depolarized dynamic light scattering journal August 2015
Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200 journal August 2015
Serial Femtosecond Crystallography of G Protein-Coupled Receptors journal December 2013
Gas dynamic virtual nozzle for generation of microscopic droplet streams journal September 2008
Substrate-Mediated Oxygen Activation by Homoprotocatechuate 2,3-Dioxygenase: Intermediates Formed by a Tyrosine 257 Variant journal October 2012
Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers journal March 2014
Crystal Structures of Fe2+ Dioxygenase Superoxo, Alkylperoxo, and Bound Product Intermediates journal April 2007
Methods development for diffraction and spectroscopy studies of metalloenzymes at X-ray free-electron lasers journal July 2014
Femtosecond Crystallography with Ultrabright Electrons and X-rays: Capturing Chemistry in Action journal March 2014
Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined by Using an X-ray Laser journal November 2012
The detection and subsequent volume optimization of biological nanocrystals journal May 2015