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Title: Host-pathogen interactions: A cholera surveillance system

Journal Article · · Nature Chemical Biology

Bacterial pathogen-secreted proteases may play a key role in inhibiting a potentially widespread host-pathogen interaction. Activity-based protein profiling enabled the identification of a major Vibrio cholerae serine protease that limits the ability of a host-derived intestinal lectin to bind to the bacterial pathogen in vivo.

Research Organization:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
OSTI ID:
1322513
Report Number(s):
PNNL-SA-115724; 453040220
Journal Information:
Nature Chemical Biology, Vol. 12, Issue 4; ISSN 1552-4450
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
English

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