Magic Angle Spinning NMR Metabolomics
Journal Article
·
· Journal of Postgenomics Drug & Biomarker Development
Nuclear Magnetic Resonance (NMR) spectroscopy is a non-destructive, quantitative, reproducible, untargeted and unbiased method that requires no or minimal sample preparation, and is one of the leading analytical tools for metabonomics research [1-3]. The easy quantification and the no need of prior knowledge about compounds present in a sample associated with NMR are advantageous over other techniques [1,4]. 1H NMR is especially attractive because protons are present in virtually all metabolites and its NMR sensitivity is high, enabling the simultaneous identification and monitoring of a wide range of low molecular weight metabolites.
- Research Organization:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC05-76RL01830
- OSTI ID:
- 1314409
- Report Number(s):
- PNNL-SA-118614; 49158; 400412000
- Journal Information:
- Journal of Postgenomics Drug & Biomarker Development, Journal Name: Journal of Postgenomics Drug & Biomarker Development Journal Issue: 2 Vol. 6; ISSN 2153-0769
- Country of Publication:
- United States
- Language:
- English
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