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U.S. Department of Energy
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Kinetic comparison of {beta}-D-glucosidases of industrial importance

Conference ·
OSTI ID:127027
Most cellulases are strongly inhibited by cellobiose, the end product from their action on crystalline cellulose. {beta}-D-glucosidases are expected to influence the cost-effective use of cellulases in the biomass conversion industry because they hydrolyze cellobiose to glucose, a (usually) less inhibitory sugar. Michaelis-Menten kinetic constants and physical chemical characteristics have been determined for {beta}-D-glucosidases and cellobiases from Acidothermus cellulolyticus, Aspergillus niger, Thermotoga neapolitana, Caldocellum saccharolyticus, and Microbispora bispora. Enzymes used in this study were isolated by column chromatography and purity was verified by gel electrophoresis and capillary electrophoresis. Recommendations for use of these enzymes in industrial processes will be made based on their kinetic performance.
OSTI ID:
127027
Report Number(s):
CONF-950402--
Country of Publication:
United States
Language:
English

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