The Release 6 reference sequence of the Drosophila melanogaster genome

Hoskins, Roger A.; Carlson, Joseph W.; Wan, Kenneth H.; Park, Soo; Mendez, Ivonne; Galle, Samuel E.; Booth, Benjamin W.; Pfeiffer, Barret D.; George, Reed A.; Svirskas, Robert; Krzywinski, Martin; Schein, Jacqueline; Accardo, Maria Carmela; Damia, Elisabetta; Messina, Giovanni; Méndez-Lago, María; de Pablos, Beatriz; Demakova, Olga V.; Andreyeva, Evgeniya N.; Boldyreva, Lidiya V.; Marra, Marco; Carvalho, A. Bernardo; Dimitri, Patrizio; Villasante, Alfredo; Zhimulev, Igor F.; Rubin, Gerald M.; Karpen, Gary H.; Celniker, Susan E.

doi:10.1101/gr.185579.114

Title: The Release 6 reference sequence of the Drosophila melanogaster genome

Journal Article · Wed Jan 14 00:00:00 EST 2015 · Genome Research

DOI:https://doi.org/10.1101/gr.185579.114· OSTI ID:1257379

Hoskins, Roger A. ^[1]; Carlson, Joseph W. ^[2]; Wan, Kenneth H. ^[1]; Park, Soo ^[1]; Mendez, Ivonne ^[1]; Galle, Samuel E. ^[1]; Booth, Benjamin W. ^[1]; Pfeiffer, Barret D. ^[3]; George, Reed A. ^[3]; Svirskas, Robert ^[3]; Krzywinski, Martin ^[4]; Schein, Jacqueline ^[4]; Accardo, Maria Carmela ^[5]; Damia, Elisabetta ^[5]; Messina, Giovanni ^[5]; Méndez-Lago, María ^[6]; de Pablos, Beatriz ^[6]; Demakova, Olga V. ^[7]; Andreyeva, Evgeniya N. ^[7]; Boldyreva, Lidiya V. ^[7] more »

Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States)
Howard Hughes Medical Inst., Ashburn, VA (United States). Janelia Farm Research Campus
BC Cancer Agency, Vancouver, BC (Canada)
Sapienza Univ. of Rome (Italy)
Autonomous Univ. of Madrid (Spain)
Russian Academy of Sciences (RAS), Moscow (Russian Federation)
Federal Univ. of Rio de Janeiro (Brazil)
Russian Academy of Sciences (RAS), Moscow (Russian Federation); Novosibirsk State Univ. (Russian Federation)

Drosophila melanogaster plays an important role in molecular, genetic, and genomic studies of heredity, development, metabolism, behavior, and human disease. The initial reference genome sequence reported more than a decade ago had a profound impact on progress in Drosophila research, and improving the accuracy and completeness of this sequence continues to be important to further progress. We previously described improvement of the 117-Mb sequence in the euchromatic portion of the genome and 21 Mb in the heterochromatic portion, using a whole-genome shotgun assembly, BAC physical mapping, and clone-based finishing. Here, we report an improved reference sequence of the single-copy and middle-repetitive regions of the genome, produced using cytogenetic mapping to mitotic and polytene chromosomes, clone-based finishing and BAC fingerprint verification, ordering of scaffolds by alignment to cDNA sequences, incorporation of other map and sequence data, and validation by whole-genome optical restriction mapping. These data substantially improve the accuracy and completeness of the reference sequence and the order and orientation of sequence scaffolds into chromosome arm assemblies. Representation of the Y chromosome and other heterochromatic regions is particularly improved. The new 143.9-Mb reference sequence, designated Release 6, effectively exhausts clone-based technologies for mapping and sequencing. Highly repeat-rich regions, including large satellite blocks and functional elements such as the ribosomal RNA genes and the centromeres, are largely inaccessible to current sequencing and assembly methods and remain poorly represented. In conclusion, further significant improvements will require sequencing technologies that do not depend on molecular cloning and that produce very long reads.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

Grant/Contract Number:: AC02- 05CH11231; AC0376SF00098; 13-04-40137; 12-04-00874-a; BFU2011-30295-C02-01; R01 GM064590

OSTI ID:: 1257379

Journal Information:: Genome Research, Vol. 25, Issue 3; ISSN 1088-9051

Publisher:: Cold Spring Harbor Laboratory PressCopyright Statement

Country of Publication:: United States

Language:: English

Citation Metrics:

Cited by: 226 works

Citation information provided by
Web of Science

References (57)

Dodeca satellite: a conserved G+C-rich satellite from the centromeric heterochromatin of Drosophila melanogaster. Abad, J. P.; Carmena, M.; Baars, S. Proceedings of the National Academy of Sciences, Vol. 89, Issue 10 https://doi.org/10.1073/pnas.89.10.4663	journal	May 1992
Pericentromeric regions containing 1.688 satellite DNA sequences show anti-kinetochore antibody staining in prometaphase chromosomes of Drosophila melanogaster Abad, J. P.; Agudo, M.; Molina, I. Molecular Genetics and Genomics, Vol. 264, Issue 4 https://doi.org/10.1007/s004380000331	journal	November 2000
Genomic and cytological analysis of the Y chromosome of Drosophila melanogaster: telomere-derived sequences at internal regions Abad, José P.; de Pablos, Beatriz; Agudo, Marta Chromosoma, Vol. 113, Issue 6 https://doi.org/10.1007/s00412-004-0318-0	journal	November 2004
Genomic Analysis of Drosophila melanogaster Telomeres: Full-length Copies of HeT-A and TART Elements at Telomeres Abad, José P.; de Pablos, Beatriz; Osoegawa, Kazutoyo Molecular Biology and Evolution, Vol. 21, Issue 9 https://doi.org/10.1093/molbev/msh174	journal	September 2004
Fluorescence in situ Hybridization with Bacterial Artificial Chromosomes (BACs) to Mitotic Heterochromatin of Drosophila Accardo, Maria Carmela; Dimitri, Patrizio Methods in Molecular Biology https://doi.org/10.1007/978-1-60761-789-1_30	book	January 2010
The Genome Sequence of Drosophila melanogaster Adams, M. D. Science, Vol. 287, Issue 5461 https://doi.org/10.1126/science.287.5461.2185	journal	March 2000
Centromeres from telomeres? The centromeric region of the Y chromosome of Drosophila melanogaster contains a tandem array of telomeric HeT-A- and TART-related sequences Agudo, M.; Losada, A.; Abad, J. P. Nucleic Acids Research, Vol. 27, Issue 16 https://doi.org/10.1093/nar/27.16.3318	journal	August 1999
High-resolution analysis of Drosophila heterochromatin organization using SuUR Su(var)3-9 double mutants Andreyeva, E. N.; Kolesnikova, T. D.; Demakova, O. V. Proceedings of the National Academy of Sciences, Vol. 104, Issue 31 https://doi.org/10.1073/pnas.0704690104	journal	July 2007
Structural organization and diversification of Y-linked sequences comprising Su(Ste) genes in Drosophila melanogaster Balakireva, M. D.; Shevelyov, Yu. Ya.; Nurminsky, D. I. Nucleic Acids Research, Vol. 20, Issue 14 https://doi.org/10.1093/nar/20.14.3731	journal	January 1992
Genetic analysis of the brahma gene of Drosophila melanogaster and polytene chromosome subdivisions 72AB. Brizuela, B. J.; Elfring, L.; Ballard, J. Genetics, Vol. 137, Issue 3 https://doi.org/10.1093/genetics/137.3.803	journal	July 1994
Y chromosomal fertility factors kl-2 and kl-3 of Drosophila melanogaster encode dynein heavy chain polypeptides Carvalho, A. B.; Lazzaro, B. P.; Clark, A. G. Proceedings of the National Academy of Sciences, Vol. 97, Issue 24 https://doi.org/10.1073/pnas.230438397	journal	November 2000
Identification of five new genes on the Y chromosome of Drosophila melanogaster Carvalho, A. B.; Dobo, B. A.; Vibranovski, M. D. Proceedings of the National Academy of Sciences, Vol. 98, Issue 23 https://doi.org/10.1073/pnas.231484998	journal	October 2001
Finishing a whole-genome shotgun: Release 3 of the Drosophila melanogastereuchromatic genome sequence Celniker, Susan E.; Wheeler, David A.; Kronmiller, Brent Genome Biology, Vol. 3, Issue 12, p. research0079.1 https://doi.org/10.1186/gb-2002-3-12-research0079	journal	January 2002
Drosophila mitochondrial DNA: a novel gene order Clary, Douglas O.; Goddard, Judy M.; Martin, Susan C. Nucleic Acids Research, Vol. 10, Issue 21 https://doi.org/10.1093/nar/10.21.6619	journal	January 1982
FISH analysis of Drosophila melanogaster heterochromatin using BACs and P elements Vern�, Fiammetta; Dimitri, Patrizio; Corradini, Nicoletta Chromosoma, Vol. 112, Issue 1 https://doi.org/10.1007/s00412-003-0241-9	journal	July 2003
The SU(VAR)3-9/HP1 Complex Differentially Regulates the Compaction State and Degree of Underreplication of X Chromosome Pericentric Heterochromatin in Drosophila melanogaster Demakova, Olga V.; Pokholkova, Galina V.; Kolesnikova, Tatyana D. Genetics, Vol. 175, Issue 2 https://doi.org/10.1534/genetics.106.062133	journal	February 2007
FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations dos Santos, G.; Schroeder, A. J.; Goodman, J. L. Nucleic Acids Research, Vol. 43, Issue D1 https://doi.org/10.1093/nar/gku1099	journal	November 2014
A Technique of Transplantation for Drosophila Ephrussi, Boris; Beadle, G. W. The American Naturalist, Vol. 70, Issue 728 https://doi.org/10.1086/280658	journal	May 1936
Software for Automated Analysis of DNA Fingerprinting Gels Fuhrmann, Daniel R.; Krzywinski, Martin I.; Chiu, Readman Genome Research, Vol. 13, Issue 5 https://doi.org/10.1101/gr.904303	journal	May 2003
Functional Elements in Drosophila Melanogaster Heterochromatin Gatti, Maurizio; Pimpinelli, Sergio Annual Review of Genetics, Vol. 26, Issue 1 https://doi.org/10.1146/annurev.ge.26.120192.001323	journal	December 1992
Chapter 21 Looking at Drosophila Mitotic Chromosomes Gatti, Maurizio; Bonaccorsi, Silvia; Pimpinelli, Sergio Methods in Cell Biology https://doi.org/10.1016/S0091-679X(08)60924-3	book	January 1994
A fertility region on the Y chromosome of Drosophila melanogaster encodes a dynein microtubule motor Gepner, J.; Hays, T. S. Proceedings of the National Academy of Sciences, Vol. 90, Issue 23 https://doi.org/10.1073/pnas.90.23.11132	journal	December 1993
The developmental transcriptome of Drosophila melanogaster Graveley, Brenton R.; Brooks, Angela N.; Carlson, Joseph W. Nature, Vol. 471, Issue 7339 https://doi.org/10.1038/nature09715	journal	December 2010
Mapping the pericentric heterochromatin by comparative genomic hybridization analysis and chromosome deletions in Drosophila melanogaster He, Bing; Caudy, Amy; Parsons, Lance Genome Research, Vol. 22, Issue 12 https://doi.org/10.1101/gr.137406.112	journal	June 2012
A BAC-Based Physical Map of the Major Autosomes of Drosophila melanogaster Hoskins, Roger A.; Nelson, Catherine R.; Berman, Benjamin P. Science, Vol. 287, Issue 5461 https://doi.org/10.1126/science.287.5461.2271	journal	March 2000
Heterochromatic sequences in a Drosophila whole-genome shotgun assembly Hoskins, Roger A.; Smith, Christopher D.; Carlson, Joseph W. Genome Biology, Vol. 3, Issue 12 https://doi.org/10.1186/gb-2002-3-12-research0085	journal	January 2002
Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin Hoskins, R. A.; Carlson, J. W.; Kennedy, C. Science, Vol. 316, Issue 5831 https://doi.org/10.1126/science.1139816	journal	June 2007
Finishing the euchromatic sequence of the human genome Nature, Vol. 431, Issue 7011, p. 931-945 https://doi.org/10.1038/nature03001	journal	October 2004
THE GENETIC AND CYTOLOGICAL ORGANIZATION OF THE Y CHROMOSOME OF DROSOPHILA MELANOGASTER Kennison, James A. Genetics, Vol. 98, Issue 3 https://doi.org/10.1093/genetics/98.3.529	journal	July 1981
Low conservation of gene content in the Drosophila Y chromosome Koerich, Leonardo B.; Wang, Xiaoyun; Clark, Andrew G. Nature, Vol. 456, Issue 7224 https://doi.org/10.1038/nature07463	journal	November 2008
Functional Copies of the Mst77F Gene on the Y Chromosome of Drosophila melanogaster Krsticevic, Flavia J.; Santos, Henrique L.; Januário, Suelen Genetics, Vol. 184, Issue 1 https://doi.org/10.1534/genetics.109.107516	journal	January 2010
Versatile and open software for comparing large genomes Kurtz, Stefan; Phillippy, Adam; Delcher, Arthur L. Genome Biology, Vol. 5, Issue 2, R12 https://doi.org/10.1186/gb-2004-5-2-r12	journal	January 2004
The analysis of Circe, an LTR retrotransposon of Drosophila melanogaster, suggests that an insertion of non-LTR retrotransposons into LTR elements can create chimeric retroelements Losada, A.; Abad, J. P.; Agudo, M. Molecular Biology and Evolution, Vol. 16, Issue 10 https://doi.org/10.1093/oxfordjournals.molbev.a026044	journal	October 1999
Long-range analysis of the centromeric region of Drosophila melanogaster chromosome 3 Losada, Ana; Abad, José P.; Agudo, Marta Chromosome Research, Vol. 8, Issue 7, p. 651-653 https://doi.org/10.1023/A:1009250411192	journal	January 2000
High Throughput Fingerprint Analysis of Large-Insert Clones Marra, Marco A.; Kucaba, Tamara A.; Dietrich, Nicole L. Genome Research, Vol. 7, Issue 11 https://doi.org/10.1101/gr.7.11.1072	journal	November 1997
A map for sequence analysis of the Arabidopsis thaliana genome Marra, Marco; Kucaba, Tamara; Sekhon, Mandeep Nature Genetics, Vol. 22, Issue 3 https://doi.org/10.1038/10327	journal	July 1999
Subtelomeres in Drosophila and Other Diptera Mason, James M.; Villasante, Alfredo Subtelomeres https://doi.org/10.1007/978-3-642-41566-1_12	book	December 2013
Novel sequencing strategy for repetitive DNA in a Drosophila BAC clone reveals that the centromeric region of the Y chromosome evolved from a telomere† Méndez-Lago, María; Wild, Jadwiga; Whitehead, Siobhan L. Nucleic Acids Research, Vol. 37, Issue 7 https://doi.org/10.1093/nar/gkp085	journal	February 2009
A Large Palindrome With Interchromosomal Gene Duplications in the Pericentromeric Region of the D. melanogaster Y Chromosome Mendez-Lago, M.; Bergman, C. M.; de Pablos, B. Molecular Biology and Evolution, Vol. 28, Issue 7 https://doi.org/10.1093/molbev/msr034	journal	February 2011
A Whole-Genome Assembly of Drosophila Myers, E. W. Science, Vol. 287, Issue 5461 https://doi.org/10.1126/science.287.5461.2196	journal	March 2000
An Extracellular Interactome of Immunoglobulin and LRR Proteins Reveals Receptor-Ligand Networks Özkan, Engin; Carrillo, Robert A.; Eastman, Catharine L. Cell, Vol. 154, Issue 1 https://doi.org/10.1016/j.cell.2013.06.006	journal	July 2013
Genetic analysis of Stellate elements of Drosophila melanogaster. Palumbo, G.; Bonaccorsi, S.; Robbins, L. G. Genetics, Vol. 138, Issue 4 https://doi.org/10.1093/genetics/138.4.1181	journal	December 1994
Gypsy transposition correlates with the production of a retroviral envelope-like protein under the tissue-specific control of the Drosophila flamenco gene. Pélisson, A.; Song, S. U.; Prud'homme, N. The EMBO Journal, Vol. 13, Issue 18 https://doi.org/10.1002/j.1460-2075.1994.tb06760.x	journal	September 1994
Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin Riddle, N. C.; Minoda, A.; Kharchenko, P. V. Genome Research, Vol. 21, Issue 2 https://doi.org/10.1101/gr.110098.110	journal	December 2010
Duplicated rDNA sequences of variable lengths flanking the short type I insertions in the rDNA of Drosophila melanogaster Roiha, Heli; Glover, David M. Nucleic Acids Research, Vol. 9, Issue 21 https://doi.org/10.1093/nar/9.21.5521	journal	January 1981
Drosophila melanogaster male germ line-specific transcripts with autosomal and Y-linked genes. Russell, S. R.; Kaiser, K. Genetics, Vol. 134, Issue 1 https://doi.org/10.1093/genetics/134.1.293	journal	May 1993
Mutations in Potassium Channel Kir2.6 Cause Susceptibility to Thyrotoxic Hypokalemic Periodic Paralysis Ryan, Devon P.; Dias da Silva, Magnus R.; Soong, Tuck Wah Cell, Vol. 140, Issue 1 https://doi.org/10.1016/j.cell.2009.12.024	journal	January 2010
The XNP remodeler targets dynamic chromatin in Drosophila Schneiderman, J. I.; Sakai, A.; Goldstein, S. Proceedings of the National Academy of Sciences, Vol. 106, Issue 34 https://doi.org/10.1073/pnas.0905816106	journal	August 2009
Myosins: a diverse superfamily Sellers, James R. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1496, Issue 1 https://doi.org/10.1016/S0167-4889(00)00005-7	journal	March 2000
Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures Stark, Alexander; Lin, Michael F.; Kheradpour, Pouya Nature, Vol. 450, Issue 7167 https://doi.org/10.1038/nature06340	journal	November 2007
Sequence Analysis of a Functional Drosophila Centromere Sun, X. Genome Research, Vol. 13, Issue 2 https://doi.org/10.1101/gr.681703	journal	February 2003
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster Venken, Koen J. T.; Carlson, Joseph W.; Schulze, Karen L. Nature Methods, Vol. 6, Issue 6 https://doi.org/10.1038/nmeth.1331	journal	May 2009
The Sequence of the Human Genome Venter, J. Craig; Adams, Mark D.; Myers, Eugene W. Science, Vol. 291, Issue 5507 https://doi.org/10.1126/science.1058040	journal	February 2001
Two New Y-Linked Genes in Drosophila melanogaster Vibranovski, Maria D.; Koerich, Leonardo B.; Carvalho, A. Bernardo Genetics, Vol. 179, Issue 4 https://doi.org/10.1534/genetics.108.086819	journal	August 2008
A Strategy for Mapping the Heterochromatin of Chromosome 2 of Drosophila Melanogaster Yasuhara, Jiro C.; Marchetti, Marcella; Fanti, Laura Genetica, Vol. 117, Issue 2/3, p. 217-226 https://doi.org/10.1023/A:1022948229580	journal	January 2003
Distribution, evolution, and diversity of retrotransposons at the flamenco locus reflect the regulatory properties of piRNA clusters Zanni, V.; Eymery, A.; Coiffet, M. Proceedings of the National Academy of Sciences, Vol. 110, Issue 49 https://doi.org/10.1073/pnas.1313677110	journal	November 2013
Validation of rice genome sequence by optical mapping Zhou, Shiguo; Bechner, Michael C.; Place, Michael BMC Genomics, Vol. 8, Issue 1 https://doi.org/10.1186/1471-2164-8-278	journal	January 2007

Cited By (102)

FlyBase at 25: looking to the future Gramates, L. Sian; Marygold, Steven J.; Santos, Gilberto dos Nucleic Acids Research, Vol. 45, Issue D1 https://doi.org/10.1093/nar/gkw1016	journal	October 2016
A fast‐evolving X‐linked duplicate of importin‐α2 is overexpressed in sex‐ratio drive in Drosophila neotestacea Pieper, Kathleen E.; Unckless, Robert L.; Dyer, Kelly A. Molecular Ecology https://doi.org/10.1111/mec.14928	journal	December 2018
Whole genome resequencing of a laboratory-adapted Drosophila melanogaster population sample Gilks, William P.; Pennell, Tanya M.; Flis, Ilona F1000Research, Vol. 5 https://doi.org/10.12688/f1000research.9912.3	journal	January 2016
Pervasive epigenetic effects of Drosophila euchromatic transposable elements impact their evolution Lee, Yuh Chwen G.; Karpen, Gary H. eLife, Vol. 6 https://doi.org/10.7554/elife.25762	journal	July 2017
Novel insights into endogenous RNA viral elements in Ixodes scapularis and other arbovirus vector genomes Russo, Alice G.; Kelly, Andrew G.; Enosi Tuipulotu, Daniel Virus Evolution, Vol. 5, Issue 1 https://doi.org/10.1093/ve/vez010	journal	January 2019
Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies Comeron, Josep M. Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 372, Issue 1736 https://doi.org/10.1098/rstb.2016.0471	journal	November 2017
Multi-faceted analysis provides little evidence for recurrent whole-genome duplications during hexapod evolution Roelofs, Dick; Zwaenepoel, Arthur; Sistermans, Tom BMC Biology, Vol. 18, Issue 1 https://doi.org/10.1186/s12915-020-00789-1	journal	May 2020
Whole genome resequencing of a laboratory-adapted Drosophila melanogaster population sample Gilks, William P.; Pennell, Tanya M.; Flis, Ilona F1000Research, Vol. 5 https://doi.org/10.12688/f1000research.9912.1	journal	January 2016
X-linkage is not a general inhibitor of tissue-specific gene expression in Drosophila melanogaster Argyridou, E.; Huylmans, A. K.; Königer, A. Heredity, Vol. 119, Issue 1 https://doi.org/10.1038/hdy.2017.12	journal	March 2017
Heterochromatin-enriched assemblies reveal the sequence and organization of the Drosophila melanogaster Y chromosome Chang, Ching-Ho; Larracuente, Amanda M. Genetics https://doi.org/10.1101/363101	journal	July 2018
Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis Fingerhut, Jaclyn M.; Moran, Jessica V.; Yamashita, Yukiko M. PLOS Genetics, Vol. 15, Issue 5 https://doi.org/10.1371/journal.pgen.1008028	journal	May 2019
Independent origins of resistance or susceptibility of parasitic wasps to a defensive symbiont Mateos, Mariana; Winter, Lauryn; Winter, Caitlyn Ecology and Evolution, Vol. 6, Issue 9 https://doi.org/10.1002/ece3.2085	journal	March 2016
A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons Lepesant, Julie M. J.; Iampietro, Carole; Galeota, Eugenia Nucleic Acids Research, Vol. 48, Issue 3 https://doi.org/10.1093/nar/gkz1142	journal	December 2019
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation Grobler, Yolande; Yun, Chi Y.; Kahler, DAvid J. PLOS Pathogens https://doi.org/10.1101/380485	journal	July 2018
The Molecular and Genetic Characterization of Second Chromosome Balancers in Drosophila melanogaster Miller, Danny E.; Cook, Kevin R.; Hemenway, Elizabeth A. G3: Genes\|Genomes\|Genetics, Vol. 8, Issue 4 https://doi.org/10.1534/g3.118.200021	journal	February 2018
The Y chromosome contributes to sex-specific aging in Drosophila Brown, Emily J.; Nguyen, Alison H.; Bachtrog, Doris Nature Ecology & Evolution , Vol. 4, Issue p. 853-862 https://doi.org/10.1101/156042	journal	September 2019
Paternal Induction of Hybrid Dysgenesis in Drosophila melanogaster Is Weakly Correlated with Both P -Element and hobo Element Dosage Srivastav, Satyam P.; Kelleher, Erin S. G3: Genes\|Genomes\|Genetics, Vol. 7, Issue 5 https://doi.org/10.1534/g3.117.040634	journal	March 2017
Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity Wang, Luyang; Barbash, Daniel A.; Kelleher, Erin S. PLOS Genetics, Vol. 16, Issue 6 https://doi.org/10.1371/journal.pgen.1008861	journal	June 2020
SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies Goel, Manish; Sun, Hequan; Jiao, Wen-Biao Genome Biology, Vol. 20, Issue 1 https://doi.org/10.1186/s13059-019-1911-0	journal	December 2019
Characterization of Drosophila Nidogen / entactin reveals roles in basement membrane stability, barrier function and nervous system patterning Wolfstetter, Georg; Dahlitz, Ina; Pfeifer, Kathrin Development, Vol. 146, Issue 2 https://doi.org/10.1242/dev.168948	journal	December 2018
QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P- element transposition in the Drosophila female germline Kelleher, Erin S.; Jaweria, Jaweria; Akoma, Uchechukwu PLOS Biology https://doi.org/10.1101/282541	journal	June 2018
Dosage Compensation of X-Linked Muller Element F Genes but Not X-Linked Transgenes in the Australian Sheep Blowfly Linger, Rebecca J.; Belikoff, Esther J.; Scott, Maxwell J. PLOS ONE, Vol. 10, Issue 10 https://doi.org/10.1371/journal.pone.0141544	journal	October 2015
Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits Chakraborty, Mahul; Emerson, J. J.; Macdonald, Stuart J. Nature Communications, Vol. 10, Issue 1 https://doi.org/10.1038/s41467-019-12884-1	journal	October 2019
Single-molecule sequencing resolves the detailed structure of complex satellite DNA loci in Drosophila melanogaster Khost, Daniel E.; Eickbush, Danna G.; Larracuente, Amanda M. Genome Research, Vol. 27, Issue 5 https://doi.org/10.1101/gr.213512.116	journal	April 2017
Gene Regulatory Variation in Drosophila melanogaster Renal Tissue Glaser-Schmitt, Amanda; Zečić, Aleksandra; Parsch, John Genetics, Vol. 210, Issue 1 https://doi.org/10.1534/genetics.118.301073	journal	July 2018
Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells Dattani, Anish; Kao, Damian; Mihaylova, Yuliana Genome Research https://doi.org/10.1101/122135	journal	August 2018
Direct interrogation of the role of H3K9 in metazoan heterochromatin function Penke, Taylor J. R.; McKay, Daniel J.; Strahl, Brian D. Genes & Development, Vol. 30, Issue 16 https://doi.org/10.1101/gad.286278.116	journal	August 2016
Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons Sapiro, Anne L.; Freund, Emily C.; Restrepo, Lucas Cell Reports, Vol. 31, Issue 7 https://doi.org/10.1016/j.celrep.2020.107654	journal	May 2020
The structure of an endogenous Drosophila centromere reveals the prevalence of tandemly repeated sequences able to form i-motifs Garavís, Miguel; Méndez-Lago, María; Gabelica, Valérie Scientific Reports, Vol. 5, Issue 1 https://doi.org/10.1038/srep13307	journal	August 2015
A hybrid de novo genome assembly of the honeybee, Apis mellifera, with chromosome-length scaffolds Wallberg, Andreas; Bunikis, Ignas; Pettersson, Olga Vinnere BMC Genomics, Vol. 20, Issue 1 https://doi.org/10.1186/s12864-019-5642-0	journal	April 2019
Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila Rech, Gabriel E.; Bogaerts-Márquez, María; Barrón, Maite G. PLOS Genetics, Vol. 15, Issue 2 https://doi.org/10.1371/journal.pgen.1007900	journal	February 2019
Islands of retroelements are the major components of Drosophila centromeres Chang, Ching-Ho; Chavan, Ankita; Palladino, Jason PLOS Biology https://doi.org/10.1101/537357	journal	February 2019
Hawaiian Drosophila genomes: size variation and evolutionary expansions Craddock, Elysse M.; Gall, Joseph G.; Jonas, Mark Genetica, Vol. 144, Issue 1 https://doi.org/10.1007/s10709-016-9882-5	journal	January 2016
Birth of a new gene on the Y chromosome of Drosophila melanogaster Carvalho, Antonio Bernardo; Vicoso, Beatriz; Russo, Claudia A. M. Proceedings of the National Academy of Sciences, Vol. 112, Issue 40 https://doi.org/10.1073/pnas.1516543112	journal	September 2015
Establishment and evolution of heterochromatin Liu, Jing; Ali, Mujahid; Zhou, Qi Annals of the New York Academy of Sciences, Vol. 1476, Issue 1 https://doi.org/10.1111/nyas.14303	journal	February 2020
Efficient expression of genes in the Drosophila germline using a UAS-promoter free of interference by Hsp70 piRNAs Deluca, Steven Z.; Spalding, Allan C. Genetics https://doi.org/10.1101/274589	journal	March 2018
Fine-Scale Position Effects Shape the Distribution of Inversion Breakpoints in Drosophila melanogaster McBroome, Jakob; Liang, David; Corbett-Detig, Russell Genome Biology and Evolution, Vol. 12, Issue 8 https://doi.org/10.1093/gbe/evaa103	journal	May 2020
Two modes of transvection at the eyes absent gene of Drosophila demonstrate plasticity in transcriptional regulatory interactions in cis and in trans Tian, Katherine; Henderson, Rachel E.; Parker, Reyna PLOS Genetics, Vol. 15, Issue 5 https://doi.org/10.1371/journal.pgen.1008152	journal	May 2019
HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila Qiu, Chen; Zhang, Yu; Fan, Yu-Jie Journal of Molecular Cell Biology, Vol. 11, Issue 2 https://doi.org/10.1093/jmcb/mjy029	journal	May 2018
CRISPR Mutants of Three Y Chromosome Genes Suggest Gradual Evolution of Fertility Functions in Drosophila melanogaster Hafezi, Yassi; Sruba, Samantha R.; Tarrash, Steven R. Genetics https://doi.org/10.1101/2020.01.30.926543	journal	January 2020
De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture Mahajan, Shivani; Wei, Kevin H. -C.; Nalley, Matthew J. PLOS Biology, Vol. 16, Issue 7 https://doi.org/10.1371/journal.pbio.2006348	journal	July 2018
Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity Wang, Luyang; Barbash, Daniel A.; Kelleher, Erin S. PLOS Genetics https://doi.org/10.1101/521773	journal	January 2020
Zinc finger RNA binding protein Zn72D regulates ADAR-mediated RNA editing in neurons Sapiro, Anne L.; Freund, Emily C.; Restrepo, Lucas Cell Reports https://doi.org/10.1101/631986	journal	May 2019
Centromere-proximal meiotic crossovers in Drosophila melanogaster are suppressed by both highly-repetitive heterochromatin and the centromere effect Hartmann, Michaelyn; Umbanhowar, James; Sekelsky, Jeff Genetics https://doi.org/10.1101/637561	journal	May 2019
Arp2/3 and Unc45 maintain heterochromatin stability in Drosophila polytene chromosomes Dialynas, George; Delabaere, Laetitia; Chiolo, Irene Experimental Biology and Medicine, Vol. 244, Issue 15 https://doi.org/10.1177/1535370219862282	journal	July 2019
Regulators of Long-Term Memory Revealed by Mushroom Body-Specific Gene Expression Profiling in Drosophila melanogaster Widmer, Yves F.; Bilican, Adem; Bruggmann, Rémy Genetics, Vol. 209, Issue 4 https://doi.org/10.1534/genetics.118.301106	journal	June 2018
Rapid evolution of piRNA-mediated silencing of an invading transposable element was driven by abundant de novo mutations Zhang, Shuo; Kelleher, Erin S. Genome Research https://doi.org/10.1101/611350	journal	January 2020
A toolset to study functions of Cytosolic non-specific dipeptidase 2 (CNDP2) using Drosophila as a model organism Andreyeva, Evgeniya N.; Ogienko, Anna A.; Dubatolova, Tatiana D. BMC Genetics, Vol. 20, Issue S1 https://doi.org/10.1186/s12863-019-0726-z	journal	March 2019
Heterochromatic hues of transcription—the diverse roles of noncoding transcripts from constitutive heterochromatin Saha, Parna; Mishra, Rakesh K. The FEBS Journal, Vol. 286, Issue 23 https://doi.org/10.1111/febs.15104	journal	August 2019
Introgressive and horizontal acquisition of Wolbachia by Drosophila yakuba -clade hosts and horizontal transfer of incompatibility loci between distantly related Wolbachia Cooper, Brandon S.; Vanderpool, Dan; Conner, William R. Genetics, Vol. 212, Issue 4, p. 1399-1419 https://doi.org/10.1101/551036	journal	August 2019
flyDIVaS : A Comparative Genomics Resource for Drosophila Divergence and Selection Stanley, Craig E.; Kulathinal, Rob J. G3: Genes\|Genomes\|Genetics, Vol. 6, Issue 8 https://doi.org/10.1534/g3.116.031138	journal	May 2016
Fine-scale position effects shape the distribution of inversion breakpoints in Drosophila melanogaster McBroome, Jakob; Liang, David; Corbett-Detig, Russell Genome Biology and Evolution https://doi.org/10.1101/793364	journal	October 2019
Canu: scalable and accurate long-read assembly via adaptive k -mer weighting and repeat separation Koren, Sergey; Walenz, Brian P.; Berlin, Konstantin Genome Research, Vol. 27, Issue 5 https://doi.org/10.1101/gr.215087.116	journal	March 2017
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster Mills, Wilbur Kyle; Lee, Yuh Chwen G.; Kochendoerfer, Antje M. eLife, Vol. 8 https://doi.org/10.7554/elife.48940	journal	November 2019
New slbo-Gal4 driver lines for the analysis of border cell migration during Drosophila oogenesis Ogienko, Anna A.; Yarinich, Lyubov A.; Fedorova, Elena V. Chromosoma, Vol. 127, Issue 4 https://doi.org/10.1007/s00412-018-0676-7	journal	July 2018
Unique transposon landscapes are pervasive across Drosophila melanogaster genomes Rahman, Reazur; Chirn, Gung-wei; Kanodia, Abhay Nucleic Acids Research, Vol. 43, Issue 22 https://doi.org/10.1093/nar/gkv1193	journal	November 2015
FlyBase at 25: looking to the future. Gramates, L. Sian; Marygold, Steven; Santos, Gilberto Dos Apollo - University of Cambridge Repository https://doi.org/10.17863/cam.36529	text	January 2017
Rapid low-cost assembly of the Drosophila melanogaster reference genome using low-coverage, long-read sequencing Solares, Edwin A.; Chakraborty, Mahul; Miller, Danny E. G3: Genes\|Genomes\|Genetics https://doi.org/10.1101/267401	journal	June 2018
Rapid Low-Cost Assembly of the Drosophila melanogaster Reference Genome Using Low-Coverage, Long-Read Sequencing Solares, Edwin A.; Chakraborty, Mahul; Miller, Danny E. G3 Genes\|Genomes\|Genetics, Vol. 8, Issue 10 https://doi.org/10.1534/g3.118.200162	journal	October 2018
Stress response, behavior, and development are shaped by transposable element-induced mutations in Drosophila Rech, Gabriel E.; Bogaerts-Marquez, Maria; Barrón, Maite G. PLOS Genetics https://doi.org/10.1101/380618	journal	July 2018
Highly Contiguous Genome Assemblies of 15 Drosophila Species Generated Using Nanopore Sequencing Miller, Danny E.; Staber, Cynthia; Zeitlinger, Julia G3: Genes\|Genomes\|Genetics, Vol. 8, Issue 10 https://doi.org/10.1534/g3.118.200160	journal	August 2018
Scrutinizing the immune defence inventory of Camponotus floridanus applying total transcriptome sequencing Gupta, Shishir K.; Kupper, Maria; Ratzka, Carolin BMC Genomics, Vol. 16, Issue 1 https://doi.org/10.1186/s12864-015-1748-1	journal	July 2015
Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy Arbel, Hamutal; Basu, Sumanta; Fisher, William W. Proceedings of the National Academy of Sciences, Vol. 116, Issue 3 https://doi.org/10.1073/pnas.1808833115	journal	December 2018
Single molecule long read sequencing resolves the detailed structure of complex satellite DNA loci in Drosophila melanogaster Khost, D. E.; Eickbush, D. G.; Larracuente, A. M. Genome Research https://doi.org/10.1101/054155	journal	July 2016
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation Grobler, Yolande; Yun, Chi Y.; Kahler, David J. PLOS Pathogens, Vol. 14, Issue 11 https://doi.org/10.1371/journal.ppat.1007445	journal	November 2018
Gene Model Annotations for Drosophila melanogaster : Impact of High-Throughput Data Matthews, Beverley B.; dos Santos, Gilberto; Crosby, Madeline A. G3: Genes\|Genomes\|Genetics, Vol. 5, Issue 8 https://doi.org/10.1534/g3.115.018929	journal	June 2015
Nuclear F-actin and myosins drive relocalization of heterochromatic breaks Caridi, Christopher P.; D’Agostino, Carla; Ryu, Taehyun Nature, Vol. 559, Issue 7712 https://doi.org/10.1038/s41586-018-0242-8	journal	June 2018
Genetic and Molecular Analysis of Essential Genes in Centromeric Heterochromatin of the Left Arm of Chromosome 3 in Drosophila melanogaster Syrzycka, Monika; Hallson, Graham; Fitzpatrick, Kathleen A. G3: Genes\|Genomes\|Genetics, Vol. 9, Issue 5 https://doi.org/10.1534/g3.119.0003	journal	April 2019
Re-annotation of eight Drosophila genomes Yang, Haiwang; Jaime, Maria; Polihronakis, Maxi Life Science Alliance, Vol. 1, Issue 6 https://doi.org/10.26508/lsa.201800156	journal	December 2018
GENOME REPORT: High-quality genome assemblies of 15 Drosophila species generated using Nanopore sequencing Miller, Danny E.; Staber, Cynthia; Zeitlinger, Julia G3 Genes\|Genomes\|Genetics https://doi.org/10.1101/267393	journal	June 2018
Satellite DNA-containing gigantic introns in a unique gene expression program during Drosophila spermatogenesis Fingerhut, Jaclyn M.; Moran, Jessica V.; Yamashita, Yukiko PLOS Genetics https://doi.org/10.1101/493254	journal	December 2018
Comparative Analysis of Satellite DNA in the Drosophila melanogaster Species Complex Jagannathan, Madhav; Warsinger-Pepe, Natalie; Watase, George J. G3: Genes\|Genomes\|Genetics, Vol. 7, Issue 2 https://doi.org/10.1534/g3.116.035352	journal	December 2016
De novo assembly of a young Drosophila Y chromosome using Single-Molecule sequencing and Chromatin Conformation capture Mahajan, Shivani; Wei, Kevin; Nalley, Matthew PLOS Biology https://doi.org/10.1101/324673	journal	May 2018
Host–transposon interactions: conflict, cooperation, and cooption Cosby, Rachel L.; Chang, Ni-Chen; Feschotte, Cédric Genes & Development, Vol. 33, Issue 17-18 https://doi.org/10.1101/gad.327312.119	journal	September 2019
Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells Dattani, Anish; Kao, Damian; Mihaylova, Yuliana Genome Research, Vol. 28, Issue 10 https://doi.org/10.1101/gr.239848.118	journal	August 2018
And yet, it moves: nuclear and chromatin dynamics of a heterochromatic double-strand break Caridi, P. Christopher; Delabaere, Laetitia; Zapotoczny, Grzegorz Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 372, Issue 1731 https://doi.org/10.1098/rstb.2016.0291	journal	August 2017
SEX-DETector: A Probabilistic Approach to Study Sex Chromosomes in Non-Model Organisms Muyle, Aline; Käfer, Jos; Zemp, Niklaus ETH Zurich https://doi.org/10.3929/ethz-b-000120658	text	January 2016
SEX-DETector: A Probabilistic Approach to Study Sex Chromosomes in Non-Model Organisms Muyle, Aline; Käfer, Jos; Zemp, Niklaus Genome Biology and Evolution, Vol. 8, Issue 8 https://doi.org/10.1093/gbe/evw172	journal	August 2016
QTL mapping of natural variation reveals that the developmental regulator bruno reduces tolerance to P-element transposition in the Drosophila female germline Kelleher, Erin S.; Jaweria, Jaweria; Akoma, Uchechukwu PLOS Biology, Vol. 16, Issue 10 https://doi.org/10.1371/journal.pbio.2006040	journal	October 2018
Efficient Expression of Genes in the Drosophila Germline Using a UAS Promoter Free of Interference by Hsp70 piRNAs DeLuca, Steven Z.; Spradling, Allan C. Genetics, Vol. 209, Issue 2 https://doi.org/10.1534/genetics.118.300874	journal	April 2018
Heterochromatin-Enriched Assemblies Reveal the Sequence and Organization of the Drosophila melanogaster Y Chromosome Chang, Ching-Ho; Larracuente, Amanda M. Genetics, Vol. 211, Issue 1 https://doi.org/10.1534/genetics.118.301765	journal	November 2018
DNA sequence models of genome-wide Drosophila melanogaster Polycomb binding sites improve generalization to independent Polycomb Response Elements Bredesen, Bjørn André; Rehmsmeier, Marc Nucleic Acids Research, Vol. 47, Issue 15 https://doi.org/10.1093/nar/gkz617	journal	July 2019
On the Importance to Acknowledge Transposable Elements in Epigenomic Analyses Lerat, Emmanuelle; Casacuberta, Josep; Chaparro, Cristian Genes, Vol. 10, Issue 4 https://doi.org/10.3390/genes10040258	journal	March 2019
Arp2/3 and Unc45 maintain heterochromatin stability in Drosophila polytene chromosomes Dialynas, George; Delabaere, Laetitia; Chiolo, Irene Experimental Biology and Medicine https://doi.org/10.1101/679548	journal	June 2019
Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons Zada, D.; Bronshtein, I.; Lerer-Goldshtein, T. Nature Communications, Vol. 10, Issue 1 https://doi.org/10.1038/s41467-019-08806-w	journal	March 2019
Nuclear actin filaments in DNA repair dynamics Caridi, Christopher Patrick; Plessner, Matthias; Grosse, Robert Nature Cell Biology, Vol. 21, Issue 9 https://doi.org/10.1038/s41556-019-0379-1	journal	September 2019
Heterochromatic breaks move to the nuclear periphery to continue recombinational repair Ryu, Taehyun; Spatola, Brett; Delabaere, Laetitia Nature Cell Biology, Vol. 17, Issue 11 https://doi.org/10.1038/ncb3258	journal	October 2015
Gene Model Annotations for Drosophila melanogaster : The Rule-Benders Crosby, Madeline A.; Gramates, L. Sian; dos Santos, Gilberto G3: Genes\|Genomes\|Genetics, Vol. 5, Issue 8 https://doi.org/10.1534/g3.115.018937	journal	June 2015
Direct interrogation of the role of H3K9 in metazoan heterochromatin function Robert, Duronio,; Gregory, Matera,; Daniel, McKay, The University of North Carolina at Chapel Hill University Libraries https://doi.org/10.17615/skpd-kt93	text	January 2016
Amphioxus SYCP1: a case of retrogene replacement and co-option of regulatory elements adjacent to the ParaHox cluster Garstang, Myles G.; Ferrier, David E. K. Development Genes and Evolution, Vol. 228, Issue 1 https://doi.org/10.1007/s00427-017-0600-9	journal	January 2018
The absence of crossovers on chromosome4inDrosophila melanogaster: Imperfection or interesting exception? Hartmann, Michaelyn A.; Sekelsky, Jeff Fly, Vol. 11, Issue 4 https://doi.org/10.1080/19336934.2017.1321181	journal	May 2017
Cervantes and Quijote protect heterochromatin from aberrant recombination and lead the way to the nuclear periphery Ryu, Taehyun; Bonner, Melissa R.; Chiolo, Irene Nucleus, Vol. 7, Issue 5 https://doi.org/10.1080/19491034.2016.1239683	journal	September 2016
Invasion of the P elements: Tolerance is not futile Meiklejohn, Colin D.; Blumenstiel, Justin P. PLOS Biology, Vol. 16, Issue 10 https://doi.org/10.1371/journal.pbio.3000036	journal	October 2018
Islands of retroelements are major components of Drosophila centromeres Chang, Ching-Ho; Chavan, Ankita; Palladino, Jason PLOS Biology, Vol. 17, Issue 5 https://doi.org/10.1371/journal.pbio.3000241	journal	May 2019
Taming the giant within Bateman, Jack R.; Anderson, David J. PLOS Genetics, Vol. 15, Issue 5 https://doi.org/10.1371/journal.pgen.1008098	journal	May 2019
Identification of Bari Transposons in 23 Sequenced Drosophila Genomes Reveals Novel Structural Variants, MITEs and Horizontal Transfer Palazzo, Antonio; Lovero, Domenica; D’Addabbo, Pietro PLOS ONE, Vol. 11, Issue 5 https://doi.org/10.1371/journal.pone.0156014	journal	May 2016
Whole Genome Mapping with Feature Sets from High-Throughput Sequencing Data Pan, Yonglong; Wang, Xiaoming; Liu, Lin PLOS ONE, Vol. 11, Issue 9 https://doi.org/10.1371/journal.pone.0161583	journal	September 2016
Adenine Methylation in Drosophila Is Associated with the Tissue-Specific Expression of Developmental and Regulatory Genes Shah, Kinnary; Cao, Weihuan; Ellison, Christopher E. G3 Genes\|Genomes\|Genetics, Vol. 9, Issue 6 https://doi.org/10.1534/g3.119.400023	journal	June 2019
An Interscholastic Network To Generate LexA Enhancer Trap Lines inDrosophila Kockel, Lutz; Griffin, Catherine; Ahmed, Yaseen G3 Genes\|Genomes\|Genetics, Vol. 9, Issue 7 https://doi.org/10.1534/g3.119.400105	journal	July 2019
A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention Prange, Ruben; Thiedmann, Marcus; Bhandari, Anita Aging, Vol. 10, Issue 8 https://doi.org/10.18632/aging.101536	journal	August 2018
Drosophila As a Genetically Tractable Model for Social Insect Behavior Camiletti, Alison L.; Thompson, Graham J. Frontiers in Ecology and Evolution, Vol. 4 https://doi.org/10.3389/fevo.2016.00040	journal	April 2016
H3K9 Promotes Under-Replication of Pericentromeric Heterochromatin in Drosophila Salivary Gland Polytene Chromosomes Armstrong, Robin; Penke, Taylor; Chao, Samuel Genes, Vol. 10, Issue 2 https://doi.org/10.3390/genes10020093	journal	January 2019

Similar Records

Genome mapping and characterization of the Anopheles gambiae heterochromatin

Journal Article · Wed Aug 04 00:00:00 EDT 2010 · BMC Genomics · OSTI ID:1257379

Sharakhova, Maria V.; George, Phillip; Brusentsova, Irina V.; +4 more

A BAC-based physical map of the Drosophila buzzatii genome

Journal Article · Fri Mar 18 00:00:00 EST 2005 · Genome Research · OSTI ID:1257379

Gonzalez, Josefa; Nefedov, Michael; Bosdet, Ian; +11 more

Sequence finishing and mapping of Drosophila melanogasterheterochromatin

Journal Article · Fri Jun 15 00:00:00 EDT 2007 · Science · OSTI ID:1257379

Hoskins, Roger A; Carlson, Joseph W; Kennedy, Cameron; +11 more

Related Subjects

59 BASIC BIOLOGICAL SCIENCES

Title: The Release 6 reference sequence of the Drosophila melanogaster genome

Citation Formats

References (57)

Cited By (102)

Similar Records

Related Subjects