Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors
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journal
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September 2018 |
Cancer chromosome breakpoints cluster in gene-rich genomic regions
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journal
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December 2018 |
Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria
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journal
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June 2019 |
Distribution and difference of APOBEC‐induced mutations in the TpCpW context of HBV DNA between HCC and non‐HCC
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journal
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August 2019 |
Landscape of somatic mutations in 560 breast cancer whole-genome sequences
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journal
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May 2016 |
The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis
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journal
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September 2016 |
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
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journal
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January 2017 |
Reduced mutation rate in exons due to differential mismatch repair
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journal
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November 2017 |
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures
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journal
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March 2017 |
Hereditary breast and ovarian cancer: new genes in confined pathways
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journal
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August 2016 |
Mutational processes contributing to the development of multiple myeloma
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journal
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August 2019 |
Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis
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journal
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November 2017 |
Validating the concept of mutational signatures with isogenic cell models
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journal
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May 2018 |
Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features
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journal
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October 2018 |
Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer
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journal
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January 2019 |
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
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journal
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April 2019 |
Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes
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journal
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July 2019 |
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway
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journal
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August 2019 |
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer
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journal
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October 2019 |
The repertoire of mutational signatures in human cancer
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journal
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February 2020 |
The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies
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journal
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September 2019 |
The mutational footprints of cancer therapies
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journal
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November 2019 |
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies
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journal
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February 2020 |
Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light
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journal
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September 2019 |
Computational approaches for discovery of mutational signatures in cancer
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journal
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July 2017 |
Detecting presence of mutational signatures in cancer with confidence
|
journal
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September 2017 |
Error-prone bypass of DNA lesions during lagging strand replication is a common source of germline and cancer mutations
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posted_content
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May 2018 |
Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation
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journal
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November 2018 |
Modelling double strand break susceptibility to interrogate structural variation in cancer
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posted_content
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October 2018 |
Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light
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posted_content
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May 2019 |
Mutational signatures are jointly shaped by DNA damage and repair
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posted_content
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February 2020 |
An integrative ENCODE resource for cancer genomics
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journal
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July 2019 |
Learning mutational signatures and their multidimensional genomic properties with TensorSignatures
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posted_content
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June 2020 |
APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context
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journal
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December 2016 |
Somatic evolution and global expansion of an ancient transmissible cancer lineage
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journal
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August 2019 |
APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa
|
journal
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August 2018 |
Within-Host Variations of Human Papillomavirus Reveal APOBEC Signature Mutagenesis in the Viral Genome
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journal
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March 2018 |
Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism
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journal
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February 2019 |
Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia
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journal
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January 2020 |
Therapeutic landscape in mutational triple negative breast cancer
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journal
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July 2018 |
Reactivation of dormant anti-tumor immunity – a clinical perspective of therapeutic immune checkpoint modulation
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journal
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January 2017 |
Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline
|
journal
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July 2018 |
Mutational signature distribution varies with DNA replication timing and strand asymmetry
|
journal
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September 2018 |
Recurrent mutations at estrogen receptor binding sites alter chromatin topology and distal gene expression in breast cancer
|
journal
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November 2018 |
Modeling double strand break susceptibility to interrogate structural variation in cancer
|
journal
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February 2019 |
Hidden Markov models lead to higher resolution maps of mutation signature activity in cancer
|
journal
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July 2019 |
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer
|
journal
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May 2020 |
Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment
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journal
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April 2018 |
Recent advances in understanding the complexities of metastasis
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journal
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January 2018 |
Recent advances in understanding the complexities of metastasis
|
journal
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January 2018 |
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation
|
journal
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September 2019 |
APOBEC3A is a prominent cytidine deaminase in breast cancer
|
journal
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December 2019 |
The APOBEC3 genes and their role in cancer: insights from human papillomavirus
|
journal
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May 2019 |
Perturbations in the Replication Program Contribute to Genomic Instability in Cancer
|
journal
|
May 2017 |
Chromatin Dynamics in Genome Stability: Roles in Suppressing Endogenous DNA Damage and Facilitating DNA Repair
|
journal
|
July 2017 |
Perturbation of base excision repair sensitizes breast cancer cells to APOBEC3 deaminase-mediated mutations
|
journal
|
January 2020 |
Error-prone bypass of DNA lesions during lagging-strand replication is a common source of germline and cancer mutations
|
journal
|
December 2018 |
APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context
|
posted_content
|
May 2016 |
Computational approaches for discovery of mutational signatures in cancer
|
posted_content
|
June 2017 |
Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline
|
journal
|
July 2017 |
Polyomavirus T-Antigen Induces APOBEC3B Expression using a LXCXE-Dependent and TP53-Independent Mechanism
|
journal
|
May 2018 |
Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer
|
posted_content
|
May 2019 |
Detection and genomic characterization of a mammary-like adenocarcinoma
|
journal
|
September 2017 |
Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
|
journalarticle
|
January 2016 |
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.
|
text
|
January 2017 |
Recurrent Mutations At Estrogen Receptor Binding Sites Alter Chromatin Topology And Distal Gene Expression In Breast Cancer
|
text
|
January 2018 |
The mutational footprints of cancer therapies
|
posted_content
|
June 2019 |
BeWith: A Between-Within method to discover relationships between cancer modules via integrated analysis of mutual exclusivity, co-occurrence and functional interactions
|
journal
|
October 2017 |
Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors.
|
text
|
January 2018 |
The repertoire of mutational signatures in human cancer
|
text
|
January 2020 |
Recurrent Mutations At Estrogen Receptor Binding Sites Alter Chromatin Topology And Distal Gene Expression In Breast Cancer
|
text
|
January 2018 |
Detecting presence of mutational signatures in cancer with confidence
|
posted_content
|
May 2017 |
Hidden Markov Models Lead to Higher Resolution Maps of Mutation Signature Activity in Cancer
|
posted_content
|
August 2018 |
Computational approaches for discovery of mutational signatures in cancer.
|
text
|
January 2019 |
Validating the concept of mutational signatures with isogenic cell models.
|
text
|
January 2018 |
A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers
|
text
|
January 2017 |
Mutational signatures are jointly shaped by DNA damage and repair
|
journal
|
May 2020 |
An integrative ENCODE resource for cancer genomics
|
journal
|
July 2020 |
Mutational signatures are jointly shaped by DNA damage and repair.
|
text
|
January 2020 |
Multimodal Assessment of Estrogen Receptor mRNA Profiles to Quantify Estrogen Pathway Activity in Breast Tumors
|
journal
|
April 2017 |
The genomics of oxidative DNA damage, repair, and resulting mutagenesis
|
journal
|
January 2020 |
ESR1 mutations: Moving towards guiding treatment decision-making in metastatic breast cancer patients
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journal
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January 2017 |
A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer
|
journal
|
March 2020 |
Replication stress response in cancer stem cells as a target for chemotherapy
|
journal
|
December 2018 |
Erratum: Whole-genome sequencing of chronic lymphocytic leukaemia reveals distinct differences in the mutational landscape between IgHVmut and IgHVunmut subgroups
|
journal
|
November 2017 |
Mismatch repair prefers exons
|
journal
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November 2017 |
Nuclear topology modulates the mutational landscapes of cancer genomes
|
journal
|
October 2017 |
An integrative bioinformatics approach reveals coding and non-coding gene variants associated with gene expression profiles and outcome in breast cancer molecular subtypes
|
journal
|
March 2018 |
Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features
|
journal
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January 2019 |
Breast cancers are rare diseases—and must be treated as such
|
journal
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April 2017 |
The evolution of hematopoietic cells under cancer therapy
|
journal
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October 2020 |
Uncovering the signaling landscape controlling breast cancer cell migration identifies splicing factor PRPF4B as a metastasis driver
|
journal
|
December 2018 |
DNA Repair Footprint Uncovers Contribution of DNA Repair Mechanism to Mutational Signatures
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conference
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November 2019 |
Progressive APOBEC3B mRNA expression in distant breast cancer metastases
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journal
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January 2017 |
From genome integrity to cancer.
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journalarticle
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January 2019 |
DNA Repair Pathway Alterations in Bladder Cancer
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journal
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March 2017 |
Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity
|
journal
|
January 2017 |
BeWith: A Between-Within Method to Discover Relationships between Cancer Modules via Integrated Analysis of Mutual Exclusivity, Co-occurrence and Functional Interactions
|
text
|
January 2017 |