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Title: Capillary absorption spectrometer and process for isotopic analysis of small samples

Abstract

A capillary absorption spectrometer and process are described that provide highly sensitive and accurate stable absorption measurements of analytes in a sample gas that may include isotopologues of carbon and oxygen obtained from gas and biological samples. It further provides isotopic images of microbial communities that allow tracking of nutrients at the single cell level. It further targets naturally occurring variations in carbon and oxygen isotopes that avoids need for expensive isotopically labeled mixtures which allows study of samples taken from the field without modification. The method also permits sampling in vivo permitting real-time ambient studies of microbial communities.

Inventors:
; ; ; ; ;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1244233
Patent Number(s):
9,297,756
Application Number:
13/757,460
Assignee:
BATTELLE MEMORIAL INSTITUTE (Richland, WA) PNNL
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Patent
Resource Relation:
Patent File Date: 2013 Feb 01
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 54 ENVIRONMENTAL SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Alexander, M. Lizabeth, Kelly, James F., Sams, Robert L., Moran, James J., Newburn, Matthew K., and Blake, Thomas A.. Capillary absorption spectrometer and process for isotopic analysis of small samples. United States: N. p., 2016. Web.
Alexander, M. Lizabeth, Kelly, James F., Sams, Robert L., Moran, James J., Newburn, Matthew K., & Blake, Thomas A.. Capillary absorption spectrometer and process for isotopic analysis of small samples. United States.
Alexander, M. Lizabeth, Kelly, James F., Sams, Robert L., Moran, James J., Newburn, Matthew K., and Blake, Thomas A.. Tue . "Capillary absorption spectrometer and process for isotopic analysis of small samples". United States. doi:. https://www.osti.gov/servlets/purl/1244233.
@article{osti_1244233,
title = {Capillary absorption spectrometer and process for isotopic analysis of small samples},
author = {Alexander, M. Lizabeth and Kelly, James F. and Sams, Robert L. and Moran, James J. and Newburn, Matthew K. and Blake, Thomas A.},
abstractNote = {A capillary absorption spectrometer and process are described that provide highly sensitive and accurate stable absorption measurements of analytes in a sample gas that may include isotopologues of carbon and oxygen obtained from gas and biological samples. It further provides isotopic images of microbial communities that allow tracking of nutrients at the single cell level. It further targets naturally occurring variations in carbon and oxygen isotopes that avoids need for expensive isotopically labeled mixtures which allows study of samples taken from the field without modification. The method also permits sampling in vivo permitting real-time ambient studies of microbial communities.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 29 00:00:00 EDT 2016},
month = {Tue Mar 29 00:00:00 EDT 2016}
}

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Works referenced in this record:

High-precision optical measurements of 13C/12C isotope ratios in organic compounds at natural abundance
journal, June 2009

  • Zare, R. N.; Kuramoto, D. S.; Haase, C.
  • Proceedings of the National Academy of Sciences, Vol. 106, Issue 27, p. 10928-10932
  • DOI: 10.1073/pnas.0904230106