How many dendritic cells are required to initiate a T-cell response?
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November 2012 |
IFNγ/TNFα specific-cells and effector memory phenotype associate with active tuberculosis
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June 2013 |
A methodology for performing global uncertainty and sensitivity analysis in systems biology
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September 2008 |
Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation
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July 2010 |
Cutting Edge: Caspase-11 Limits the Response of CD8 + T Cells to Low-Abundance and Low-Affinity Antigens
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May 2015 |
The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes
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October 2005 |
Protective CD4 T Cells Targeting Cryptic Epitopes of Mycobacterium tuberculosis Resist Infection-Driven Terminal Differentiation
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February 2014 |
Competition for antigenic sites during T cell proliferation: A mathematical interpretation of in vitro data
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September 1999 |
Multiscale Computational Modeling Reveals a Critical Role for TNF-α Receptor 1 Dynamics in Tuberculosis Granuloma Formation
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February 2011 |
Visualizing how T cells collect activation signals in vivo
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February 2014 |
A cellular calculus for signal integration by T cells
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September 2000 |
Imaging the Single Cell Dynamics of CD4 + T Cell Activation by Dendritic Cells in Lymph Nodes
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October 2004 |
Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines
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May 2008 |
A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment
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February 2015 |
Do most lymphocytes in humans really reside in the gut?
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December 2007 |
Recruitment Times, Proliferation, and Apoptosis Rates during the CD8+ T-Cell Response to Lymphocytic Choriomeningitis Virus
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November 2001 |
Differential Antigen Presentation Regulates the Changing Patterns of CD8 + T Cell Immunodominance in Primary and Secondary Influenza Virus Infections
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July 2003 |
Human memory T cells: generation, compartmentalization and homeostasis
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December 2013 |
Bacillus Calmette-Guérin Vaccination of Human Newborns Induces T Cells with Complex Cytokine and Phenotypic Profiles
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February 2008 |
The integration of T cell migration, differentiation and function
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April 2013 |
T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell
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March 2005 |
Immune responses to Listeria monocytogenes
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October 2004 |
Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go?
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May 2012 |
Complete but curtailed T-cell response to very low-affinity antigen
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January 2009 |
Efficacy of BCG Vaccine in the Prevention of Tuberculosis: Meta-analysis of the Published Literature
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March 1994 |
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
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January 2008 |
Increasing Viral Dose Causes a Reversal in CD8 + T Cell Immunodominance during Primary Influenza Infection due to Differences in Antigen Presentation, T Cell Avidity, and Precursor Numbers
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December 2012 |
Estimating Lymphocyte Division and Death Rates from CFSE Data
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May 2006 |
Transcriptional control of effector and memory CD8+ T cell differentiation
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October 2012 |
Regulation of CD8 + T Cells Undergoing Primary and Secondary Responses to Infection in the Same Host
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May 2003 |
Modified vaccinia Ankara-expressing Ag85A, a novel tuberculosis vaccine, is safe in adolescents and children, and induces polyfunctional CD4+ T cells
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December 2009 |
C entral M emory and E ffector M emory T C ell S ubsets : Function, Generation, and Maintenance
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April 2004 |
Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctionalMycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations
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November 2007 |
COMPASS identifies T-cell subsets correlated with clinical outcomes
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May 2015 |
From Vaccines to Memory and Back
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October 2010 |
Tuberculosis vaccines: barriers and prospects on the quest for a transformative tool
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February 2015 |
Multi-Scale Modeling Predicts a Balance of Tumor Necrosis Factor-α and Interleukin-10 Controls the Granuloma Environment during Mycobacterium tuberculosis Infection
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July 2013 |
Models of CD8+ Responses: 1. What is the Antigen-independent Proliferation Program
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April 2003 |
Rapid Development of T Cell Memory
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June 2004 |
TNF neutralization results in disseminated disease during acute and latent M. tuberculosis infection with normal granuloma structure
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January 2010 |
Developmental Regulation of Lck Targeting to the CD8 Coreceptor Controls Signaling in Naive and Memory T Cells
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May 1999 |
Region of Difference 1 Antigen–Specific CD4 + Memory T Cells Correlate with a Favorable Outcome of Tuberculosis
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October 2006 |
Naive CD4+ T Cell Frequency Varies for Different Epitopes and Predicts Repertoire Diversity and Response Magnitude
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August 2007 |
Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion
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March 2007 |
Distinct Effector Memory CD4+ T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis
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April 2012 |
Jump-starting the immune system: prime–boosting comes of age
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February 2004 |
Tuberculosis Vaccines and Prevention of Infection
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November 2014 |
Association of mycobacterial antigen-specific CD4+ memory T cell subsets with outcome of pulmonary tuberculosis
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February 2010 |
The Impact of TCR-Binding Properties and Antigen Presentation Format on T Cell Responsiveness
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June 2009 |
Correlates of Immune Protection from Tuberculosis
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May 2007 |
Prolonged antigen presentation by immune complex–binding dendritic cells programs the proliferative capacity of memory CD8 T cells
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July 2014 |
Predicting lymph node output efficiency using systems biology
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October 2013 |
Vaccination against tuberculosis: How can we better BCG?
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May 2013 |
Naive Precursor Frequencies and MHC Binding Rather Than the Degree of Epitope Diversity Shape CD8 + T Cell Immunodominance
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July 2008 |
Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection
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June 2008 |
Identifying control mechanisms of granuloma formation during M. tuberculosis infection using an agent-based model
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December 2004 |
Delaying BCG vaccination from birth to 10 weeks of age may result in an enhanced memory CD4 T cell response
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September 2009 |
Secondary memory CD8 + T cells are more protective but slower to acquire a central–memory phenotype
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March 2006 |
Induction of multi-antigen multi-stage immune responses against Plasmodium falciparum in rhesus monkeys, in the absence of antigen interference, with heterologous DNA prime/poxvirus boost immunization
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January 2007 |
A comparison of random vs. chemotaxis-driven contacts of T cells with dendritic cells during repertoire scanning
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February 2008 |
Memory T Cell Subsets, Migration Patterns, and Tissue Residence
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March 2013 |
T lymphocyte dynamics during Listeria monocytogenes infection
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January 1999 |
A multistage tuberculosis vaccine that confers efficient protection before and after exposure
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January 2011 |
Induction of Potent and Long-Lived Antibody and Cellular Immune Responses in the Genitorectal Mucosa Could be the Critical Determinant of HIV Vaccine Efficacy
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May 2014 |
Characterizing the Dynamics of CD4+ T Cell Priming within a Lymph Node
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February 2010 |
Peptide-MHC Class II Complex Stability Governs CD4 T Cell Clonal Selection
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December 2009 |
Cross-competition of CD8 + T cells shapes the immunodominance hierarchy during boost vaccination
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August 2007 |
From crucial to negligible: Functional CD8 + T-cell responses and their dependence on CD4 + T-cell help : HIGHLIGHTS
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April 2012 |
Activation phenotype, rather than central– or effector–memory phenotype, predicts the recall efficacy of memory CD8 + T cells
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July 2007 |
Stimulation History Dictates Memory CD8 T Cell Phenotype: Implications for Prime-Boost Vaccination
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July 2006 |
Influence of time and number of antigen encounters on memory CD8 T cell development
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May 2014 |
Real-Time Manipulation of T Cell-Dendritic Cell Interactions In Vivo Reveals the Importance of Prolonged Contacts for CD4+ T Cell Activation
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October 2007 |
A Single Peptide-Major Histocompatibility Complex Ligand Triggers Digital Cytokine Secretion in CD4+ T Cells
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November 2013 |
Contemporary Analysis of MHC-Related Immunodominance Hierarchies in the CD8 + T Cell Response to Influenza A Viruses
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September 2000 |
A multi-scale approach to designing therapeutics for tuberculosis
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April 2015 |
In search of a new paradigm for protective immunity to TB
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March 2014 |
First-in-human trial of the post-exposure tuberculosis vaccine H56:IC31 in Mycobacterium tuberculosis infected and non-infected healthy adults
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August 2015 |
The multistage vaccine H56 boosts the effects of BCG to protect cynomolgus macaques against active tuberculosis and reactivation of latent Mycobacterium tuberculosis infection
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January 2012 |
Granuloma Correlates of Protection Against Tuberculosis and Mechanisms of Immune Modulation by Mycobacterium tuberculosis
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December 2012 |
Computational Modeling Predicts IL-10 Control of Lesion Sterilization by Balancing Early Host Immunity–Mediated Antimicrobial Responses with Caseation during Mycobacterium tuberculosis Infection
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December 2014 |
Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis
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July 2007 |
Harnessing the Heterogeneity of T Cell Differentiation Fate to Fine-Tune Generation of Effector and Memory T Cells
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January 2014 |
Antigen Experience Shapes Phenotype and Function of Memory Th1 Cells
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June 2013 |
Vaccines against intracellular infections requiring cellular immunity
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August 2000 |
Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes
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May 2003 |
Mycobacterium tuberculosis gene expression during adaptation to stationary phase and low-oxygen dormancy
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January 2004 |
TCR signaling requirements for activating T cells and for generating memory
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April 2012 |
CD4 T cells integrate signals delivered during successive DC encounters in vivo
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journal
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November 2005 |
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
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journal
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March 2008 |
Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial
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journal
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March 2013 |
Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8 + T Cell Responsiveness
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journal
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May 2012 |
Tuberculosis vaccine development at a divide
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journal
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January 2014 |
Decoding the dynamics of T cell–dendritic cell interactions in vivo
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journal
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February 2008 |
A Simple Mathematical Model Helps To Explain the Immunodominance of CD8 T Cells in Influenza A Virus Infections
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June 2008 |
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
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September 2002 |