Coordination of kidney organogenesis by Wnt signaling
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January 2014 |
Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength
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February 2008 |
Systemic administration of sclerostin monoclonal antibody accelerates fracture healing in the femoral osteotomy model of young rats
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January 2015 |
Impact of Diabetes on Fracture Healing
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February 2011 |
The emerging challenge in diabetes: The “metabolic memory”
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November 2012 |
Bone structure and turnover in type 2 diabetes mellitus
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March 2011 |
Sclerostin Binds to LRP5/6 and Antagonizes Canonical Wnt Signaling
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March 2005 |
Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes
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March 2013 |
Activation of Wnt/β-Catenin Signaling Increases Insulin Sensitivity through a Reciprocal Regulation of Wnt10b and SREBP-1c in Skeletal Muscle Cells
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December 2009 |
Temporal changes in systemic and local expression of bone turnover markers during six months of sclerostin antibody administration to ovariectomized rats
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October 2014 |
Bone Loss and Increased Bone Adiposity in Spontaneous and Pharmacologically Induced Diabetic Mice
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January 2007 |
Bone Density Ligand, Sclerostin, Directly Interacts With LRP5 but Not LRP5G171V to Modulate Wnt Activity
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August 2006 |
The C-terminal fragment of parathyroid hormone-related peptide promotes bone formation in diabetic mice with low-turnover osteopaenia: C-terminal PTHrP is anabolic for diabetic bone
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February 2011 |
Beta-Catenin Signaling Plays a Disparate Role in Different Phases of Fracture Repair: Implications for Therapy to Improve Bone Healing
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July 2007 |
Diabetes Mellitus: Does it Affect Bone?
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December 2003 |
Circulating Sclerostin Levels and Bone Turnover in Type 1 and Type 2 Diabetes
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May 2012 |
Genetic evidence that SOST inhibits WNT signaling in the limb
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June 2010 |
Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein
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March 2001 |
Bone Matrix Quality After Sclerostin Antibody Treatment: BONE MATRIX COMPOSITION AND SCLEROSTIN ANTIBODY
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June 2014 |
Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes
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October 2012 |
Understanding the pathology and mechanisms of type I diabetic bone loss
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January 2007 |
Prevalence and predictors of osteopenia and osteoporosis in adults with Type 1 diabetes
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January 2009 |
The effects of blood glucose control upon fracture healing in the BB Wistar rat with diabetes mellitus
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November 2002 |
Osteo-promoting effects of insulin-like growth factor I (IGF-I) in a mouse model of type 1 diabetes
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November 2013 |
Gone with the Wnts: β-Catenin, T-Cell Factor, Forkhead Box O, and Oxidative Stress in Age-Dependent Diseases of Bone, Lipid, and Glucose Metabolism
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November 2007 |
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones
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May 2011 |
Insulin-dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation
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May 2011 |
Targeted deletion of Sost distal enhancer increases bone formation and bone mass
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August 2012 |
Diabetes and Its Complications and Their Relationship with Risk of Fractures in Type 1 and 2 Diabetes
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December 2008 |
Increased callus mass and enhanced strength during fracture healing in mice lacking the sclerostin gene
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December 2011 |
Age-Related Changes in Trabecular Architecture Differ in Female and Male C57BL/6J Mice
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May 2007 |
Sclerostin monoclonal antibody enhanced bone fracture healing in an open osteotomy model in rats: Scl-Ab ENHANCED RAT OSTEOTOMY HEALING
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April 2014 |
Sclerostin Levels Associated with Inhibition of the Wnt/β-Catenin Signaling and Reduced Bone Turnover in Type 2 Diabetes Mellitus
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October 2012 |
Multiple Roles of the PI3K/PKB (Akt) Pathway in Cell Cycle Progression
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July 2003 |
Wnt Signaling and the Polarity of the Primary Body Axis
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December 2009 |
Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
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June 2010 |
Zinc supplementation inhibits the increase in osteoclastogenesis and decrease in osteoblastogenesis in streptozotocin-induced diabetic rats
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August 2013 |
Histomorphometric analysis of diabetic osteopenia in streptozotocin-induced diabetic mice: A possible role of oxidative stress
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May 2007 |
Bone mineral density and fracture risk in type-2 diabetes mellitus: the Rotterdam Study.
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June 2005 |
Hyperglycemia Diverts Dividing Osteoblastic Precursor Cells to an Adipogenic Pathway and Induces Synthesis of a Hyaluronan Matrix That Is Adhesive for Monocytes
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April 2014 |
Inhibition of the canonical Wnt pathway by high glucose can be reversed by parathyroid hormone-related protein in osteoblastic cells
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June 2013 |
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
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February 2002 |
Hyperglycemia Enhances Adipogenic Induction of Lipid Accumulation: Involvement of Extracellular Signal-Regulated Protein Kinase 1/2, Phosphoinositide 3-Kinase/Akt, and Peroxisome Proliferator-Activated Receptor γ Signaling
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September 2007 |
Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling
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April 2013 |
Production of a standard closed fracture in laboratory animal bone
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January 1984 |
The bone marrow microenvironment contributes to type I diabetes induced osteoblast death
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November 2010 |
Streptozotocin, Type I Diabetes Severity and Bone
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March 2009 |
Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats
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March 2012 |
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
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June 2005 |
Effects of sclerostin antibody on healing of a non-critical size femoral bone defect
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August 2012 |
Osteoporosis in Patients With Diabetes Mellitus
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May 2007 |
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
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June 2010 |
Diabetes Interferes with the Bone Formation by Affecting the Expression of Transcription Factors that Regulate Osteoblast Differentiation
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January 2003 |
Localization of the Gene for Sclerosteosis to the van Buchem Disease–Gene Region on Chromosome 17q12–q21
- Balemans, Wendy; Van Den Ende, Jenneke; Freire Paes-Alves, Auristela
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The American Journal of Human Genetics, Vol. 64, Issue 6
https://doi.org/10.1086/302416
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June 1999 |
Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis
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May 2005 |
An in vivo experimental study on osteopenia in diabetic rats
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October 2011 |
Sclerostin Deficiency Is Linked to Altered Bone Composition: SCLEROSTIN DEFICIENCY IS LINKED TO ALTERED BONE COMPOSITION
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September 2014 |
Management of Diabetes Mellitus: Could Simultaneous Targeting of Hyperglycemia and Oxidative Stress Be a Better Panacea?
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March 2012 |
Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus
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February 2013 |
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
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January 2010 |
Increasing duration of type 1 diabetes perturbs the strength–structure relationship and increases brittleness of bone
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April 2011 |
Intensive Insulin Therapy and Bone Mineral Density in Type 1 Diabetes Mellitus: A Prospective Study
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May 2000 |
Bone and the regulation of global energy balance
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May 2015 |
Glimepiride Promotes Osteogenic Differentiation in Rat Osteoblasts via the PI3K/Akt/eNOS Pathway in a High Glucose Microenvironment
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November 2014 |
The Influence of Diabetes Mellitus on the Healing of Closed Fractures
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July 1988 |