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Title: Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein

Journal Article · · mBio
; ; ; ;  [1]
  1. UTSMC
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Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
National Institutes of Health (NIH)
OSTI ID:
1221427
Journal Information:
mBio, Vol. 6, Issue (3) ; 05, 2015
Country of Publication:
United States
Language:
ENGLISH

References (28)

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Covalent Binding of Flavins to RnfG and RnfD in the Rnf Complex from Vibrio cholerae † journal October 2008
Syphilis Returns to China ??? With a Vengeance journal January 2006
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Structural and Thermodynamic Characterization of the Interaction between Two Periplasmic Treponema pallidum Lipoproteins that are Components of a TPR-Protein-Associated TRAP Transporter (TPAT) journal June 2012
Using the KEGG Database Resource journal June 2012
Treponema pallidum and the quest for outer membrane proteins journal June 1995
Complete Genome Sequence of Treponema pallidum, the Syphilis Spirochete journal July 1998
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Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts journal January 2008
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Genome Reduction Promotes Increase in Protein Functional Complexity in Bacteria journal October 2012
Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter journal March 2012
PHENIX: a comprehensive Python-based system for macromolecular structure solution journal January 2010
Bioenergetics and anaerobic respiratory chains of aceticlastic methanogens journal July 2014
Genetic Control of Biosynthesis and Transport of Riboflavin and Flavin Nucleotides and Construction of Robust Biotechnological Producers journal June 2011
Adaptations of anaerobic archaea to life under extreme energy limitation journal May 2014
Succinate Secreted by Trypanosoma brucei Is Produced by a Novel and Unique Glycosomal Enzyme, NADH-dependent Fumarate Reductase journal July 2002
Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. Treponema Pallidum Polypeptide Research Group. journal January 1993
What’s in a covalent bond?: On the role and formation of covalently bound flavin cofactors journal June 2009
Protein Identification and Analysis Tools on the ExPASy Server book January 2005
Cryo-Electron Tomography Elucidates the Molecular Architecture of Treponema pallidum, the Syphilis Spirochete journal October 2009
Sodium Ion Cycle in Bacterial Pathogens: Evidence from Cross-Genome Comparisons journal September 2001
Flavogenomics - a genomic and structural view of flavin-dependent proteins: Flavin-dependent proteins journal July 2011
Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. Treponema Pallidum Polypeptide Research Group journal September 1993

Cited By (8)

Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen journal October 2016
A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria journal September 2018
Structural analysis of Borrelia burgdorferi periplasmic lipoprotein BB 0365 involved in Lyme disease infection journal September 2019
Chemerin induced by Treponema pallidum predicted membrane protein Tp0965 mediates the activation of endothelial cell via MAPK signaling pathway journal July 2019
Flavin transferase: the maturation factor of flavin-containing oxidoreductases journal August 2018
NaCl promotes antibiotic resistance by reducing redox states in Vibrio alginolyticus: Na + contributes to antibiotic resistance journal October 2018
The Membrane-Bound C Subunit of Reductive Dehalogenases: Topology Analysis and Reconstitution of the FMN-Binding Domain of PceC journal April 2018
A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria. text January 2018

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