Niosh comments to DOL on risk estimates from the cadmium cohort study by L. Stayner, February 7, 1992
Technical Report
·
OSTI ID:121932
This testimony includes a table summarizing the risk estimates from fitting the multistage model to a specific cadmium cohort study. The risk estimates from fitting the multistage model to the cadmium study were intermediate between estimates derived from fitting the Cox and Poisson regression models. NIOSH further notes that the risk estimates from the Cost and Poisson models are about 50% higher than the estimates in the risk assessment report submitted earlier by NIOSH. The lifetime risk was calculated over the entire life span rather than the median life span. Lung cancer rates were used rather than respiratory cancer rates. NIOSH assumed a five stage model for the analysis, as this is the number of stages generally observed in other multistage analyses of lung cancer. The model was fit by varing the stage affected by cadmium exposure and the model fit best when NIOSH assumed that cadmium affected the third stage.
- Research Organization:
- National Inst. for Occupational Safety and Health, Cincinnati, OH (United States). Div. of Standards Development and Technology Transfer
- OSTI ID:
- 121932
- Report Number(s):
- PB--95-267779/XAB
- Country of Publication:
- United States
- Language:
- English
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