High-frequency modification of plant genes using engineered zinc-finger nucleases
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April 2009 |
Structures of Zinc Finger Domains from Transcription Factor Sp1: INSIGHTS INTO SEQUENCE-SPECIFIC PROTEIN-DNA RECOGNITION
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March 1997 |
Target Detection Assay (TDA): a versatile procedure to determine DNA blinding sites as demonstrated on SP1 protein
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January 1990 |
Nuance in the double-helix and its role in protein–DNA recognition
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April 2009 |
A census of human transcription factors: function, expression and evolution
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April 2009 |
Semisynthetic DNA-Protein Conjugates for Biosensing and Nanofabrication
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January 2010 |
DNA Recognition of C 2 H 2 Zinc-Finger Proteins. : Evidence for a Zinc-Finger-specific DNA Recognition Code
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June 1993 |
Advances in targeted genome editing
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August 2012 |
Osterix induces Col1a1 gene expression through binding to Sp1 sites in the bone enhancer and proximal promoter regions
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February 2013 |
Engineering transcription factors with novel DNA-binding specificity using comparative genomics
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March 2009 |
Progress and prospects: Zinc-finger nucleases as gene therapy agents
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September 2008 |
Initial impact of the sequencing of the human genome
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February 2011 |
SP1 transcription factors in male germ cell development and differentiation
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May 2007 |
NMR Structure of Transcription Factor Sp1 DNA Binding Domain † , ‡
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December 2004 |
Experimental determination of the evolvability of a transcription factor
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October 2009 |
Predicting DNA recognition by Cys2His2 zinc finger proteins
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November 2008 |
Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays
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February 2011 |
Zebrafish Sp1-like protein is structurally and functionally comparable to human Sp1
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March 2011 |
Self-assembly of a nanoscale DNA box with a controllable lid
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May 2009 |
Folding DNA to create nanoscale shapes and patterns
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March 2006 |
Drive Against Hotspot Motifs in Primates Implicates the PRDM9 Gene in Meiotic Recombination
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December 2009 |
Stages of emerging life —Five principles of early organization
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December 1982 |
Initial sequencing and analysis of the human genome
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February 2001 |
DNA-binding Specificity Is a Major Determinant of the Activity and Toxicity of Zinc-finger Nucleases
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February 2008 |
The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation
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June 2010 |
An optimized two-finger archive for ZFN-mediated gene targeting
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April 2012 |
Programming biomolecular self-assembly pathways
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January 2008 |
Unique DNA Binding Mode of the N-Terminal Zinc Finger of Transcription Factor Sp1 †
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May 1998 |
A zinc finger protein array for the visual detection of specific DNA sequences for diagnostic applications
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December 2010 |
Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme
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March 2012 |
Erratum: Unexpected failure rates for modular assembly of engineered zinc fingers
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June 2008 |
Zinc-finger Nucleases: The Next Generation Emerges
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July 2008 |
Assessing computational tools for the discovery of transcription factor binding sites
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January 2005 |
Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks
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December 1998 |
Deployment of new biotechnologies in plant breeding
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March 2012 |
Determination of DNA binding specificities of mutated zinc finger domains
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May 1991 |
Hierarchies in eukaryotic genome organization: Insights from polymer theory and simulations
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January 2011 |
Profiling the DNA-binding specificities of engineered Cys2His2 zinc finger domains using a rapid cell-based method
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May 2007 |
Diversity and Complexity in DNA Recognition by Transcription Factors
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May 2009 |
Studying the Evolution of Promoter Sequences: A Waiting Time Problem
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December 2010 |
Conserved expression without conserved regulatory sequence: the more things change, the more they stay the same
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February 2010 |
Engineered DNA modifying enzymes: Components of a future strategy to cure HIV/AIDS
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February 2013 |
Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells
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May 2009 |
Surprising flexibility in a conserved Hox transcription factor over 550 million years of evolution
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October 2010 |
Use of a zinc-finger consensus sequence framework and specificity rules to design specific DNA binding proteins.
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March 1993 |
Precise genome modification in the crop species Zea mays using zinc-finger nucleases
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April 2009 |
Genome editing in induced pluripotent stem cells: Genome editing in iPS cells
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April 2012 |
Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin
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December 2007 |
Genome editing with modularly assembled zinc-finger nucleases
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February 2010 |
Origins of Specificity in Protein-DNA Recognition
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June 2010 |
Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
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May 2009 |
Chromatin structure of two genomic sites for targeted transgene integration in induced pluripotent stem cells and hematopoietic stem cells
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March 2012 |
Comparison of Zinc Finger Nucleases for Use in Gene Targeting in Mammalian Cells
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April 2008 |
Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription
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January 2011 |
An improved zinc-finger nuclease architecture for highly specific genome editing
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July 2007 |
A primer to scaffolded DNA origami
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February 2011 |
Clinical trials for stem cell therapies
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May 2011 |
Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors
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June 2008 |
Zinc Finger Nucleases as tools to understand and treat human diseases
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July 2010 |
Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism.
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September 1991 |
Regulation of the activity of Sp1-related transcription factors
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September 2002 |
Specificity landscapes of DNA binding molecules elucidate biological function
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February 2010 |
Epigenetic memory in induced pluripotent stem cells
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July 2010 |
The origin of genetic information: viruses as models
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December 1993 |
Hierarchical self-assembly of DNA into symmetric supramolecular polyhedra
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March 2008 |