Conserved features of intermediates in amyloid assembly determine their benign or toxic states
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June 2012 |
Shape Complementarity at Protein/Protein Interfaces
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December 1993 |
The Amyloid State of Proteins in Human Diseases
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March 2012 |
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
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December 2009 |
Experimental Constraints on Quaternary Structure in Alzheimer's β-Amyloid Fibrils †
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January 2006 |
The Interaction of an Epidermal Growth Factor/Transforming Growth Factor α Tail Chimera with the Human Epidermal Growth Factor Receptor Reveals Unexpected Complexities
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November 1996 |
Phenolic Compounds Prevent Amyloid β-Protein Oligomerization and Synaptic Dysfunction by Site-specific Binding
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March 2012 |
EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers
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May 2008 |
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B: Imaging Amyloid in AD with PIB
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January 2004 |
Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity
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September 2012 |
RosettaLigand Docking with Full Ligand and Receptor Flexibility
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January 2009 |
Curcumin Inhibits Formation of Amyloid β Oligomers and Fibrils, Binds Plaques, and Reduces Amyloid in Vivo
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December 2004 |
Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
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May 2012 |
Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan
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March 2011 |
SOGGY: Solvent-optimized double gradient spectroscopy for water suppression. A comparison with some existing techniques
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February 2007 |
Structural properties of A protofibrils stabilized by a small molecule
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May 2005 |
Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
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April 2003 |
Towards a Pharmacophore for Amyloid
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June 2011 |
Atomic View of a Toxic Amyloid Small Oligomer
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March 2012 |
3D structure of Alzheimer's amyloid- (1-42) fibrils
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November 2005 |
ZINC − A Free Database of Commercially Available Compounds for Virtual Screening
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December 2004 |
The Amyloid-Congo Red Interface at Atomic Resolution
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May 2011 |
ROSETTALIGAND: Protein-small molecule docking with full side-chain flexibility
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November 2006 |
Natural oligomers of the amyloid-β protein specifically disrupt cognitive function
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December 2004 |
Small Molecule Microarrays Enable the Discovery of Compounds That Bind the Alzheimer’s Aβ Peptide and Reduce its Cytotoxicity
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December 2010 |
The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42
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February 2010 |
Inhibition of Alzheimer’s disease β-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: implications for Alzheimer’s therapy
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May 2001 |
Out-of-register -sheets suggest a pathway to toxic amyloid aggregates
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December 2012 |
The most infectious prion protein particles
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September 2005 |
Self-Propagating, Molecular-Level Polymorphism in Alzheimer's -Amyloid Fibrils
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January 2005 |
Amyloid-β fibrillogenesis: Structural insight and therapeutic intervention
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June 2010 |
Small Molecule Inhibitors of Aggregation Indicate That Amyloid β Oligomerization and Fibrillization Pathways Are Independent and Distinct
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February 2007 |
Molecular basis for amyloid- polymorphism
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September 2011 |
DOCK 4.0: Search strategies for automated molecular docking of flexible molecule databases
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May 2001 |
Peptide and Protein Mimetics Inhibiting Amyloid β-Peptide Aggregation
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October 2008 |
N-Methylated Peptide Inhibitors of β-Amyloid Aggregation and Toxicity. Optimization of the Inhibitor Structure †
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August 2006 |
Native protein sequences are close to optimal for their structures
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September 2000 |
Aromatic Small Molecules Remodel Toxic Soluble Oligomers of Amyloid β through Three Independent Pathways
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November 2010 |
Assessing the performance of OMEGA with respect to retrieving bioactive conformations
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March 2003 |
Heat Shock Proteins 70 and 90 Inhibit Early Stages of Amyloid β-(1–42) Aggregation in Vitro
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September 2006 |
Inhibition of Amyloid Formation
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August 2012 |
Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model
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June 2006 |
Atomic structures of amyloid cross-β spines reveal varied steric zippers
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April 2007 |
Congo red and protein aggregation in neurodegenerative diseases
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January 2007 |
Peptide Inhibitors of Beta Amyloid Aggregation
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April 2002 |
Therapeutic strategies for human amyloid diseases
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April 2002 |
Microcin Amyloid Fibrils A Are Reservoir of Toxic Oligomeric Species
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February 2012 |
Rational design of potent domain antibody inhibitors of amyloid fibril assembly
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November 2012 |
The Blue Obelisk—Interoperability in Chemical Informatics
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May 2006 |
Inhibition of Amyloid Fibril Formation by Polyphenols: Structural Similarity and Aromatic Interactions as a Common Inhibition Mechanism
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January 2006 |
Rosetta3: An Object-Oriented Software Suite for the Simulation and Design of Macromolecules
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January 2011 |
Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils
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November 2011 |
Protein Misfolding, Functional Amyloid, and Human Disease
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June 2006 |
Strategies for the Inhibition of Protein Aggregation in Human Diseases
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April 2010 |
Discovery and Structure Activity Relationship of Small Molecule Inhibitors of Toxic β-Amyloid-42 Fibril Formation
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August 2012 |
Structure of the cross-β spine of amyloid-like fibrils
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June 2005 |