Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy

Bulanov, S. S.; Esarey, E.; Schroeder, C. B.; Leemans, W. P.; Bulanov, S. V.; Margarone, D.; Korn, G.; Haberer, T.

doi:10.1103/PhysRevSTAB.18.061302

Title: Helium-3 and helium-4 acceleration by high power laser pulses for hadron therapy

Journal Article · Wed Jun 24 00:00:00 EDT 2015 · Physical Review Special Topics. Accelerators and Beams

DOI:https://doi.org/10.1103/PhysRevSTAB.18.061302· OSTI ID:1188514

Bulanov, S. S.; Esarey, E.; Schroeder, C. B.; Leemans, W. P.; Bulanov, S. V.; Margarone, D.; Korn, G.; Haberer, T.

The laser driven acceleration of ions is considered a promising candidate for an ion source for hadron therapy of oncological diseases. Though proton and carbon ion sources are conventionally used for therapy, other light ions can also be utilized. Whereas carbon ions require 400 MeV per nucleon to reach the same penetration depth as 250 MeV protons, helium ions require only 250 MeV per nucleon, which is the lowest energy per nucleon among the light ions (heavier than protons). This fact along with the larger biological damage to cancer cells achieved by helium ions, than that by protons, makes this species an interesting candidate for the laser driven ion source. Two mechanisms (magnetic vortex acceleration and hole-boring radiation pressure acceleration) of PW-class laser driven ion acceleration from liquid and gaseous helium targets are studied with the goal of producing 250 MeV per nucleon helium ion beams that meet the hadron therapy requirements. We show that He3 ions, having almost the same penetration depth as He4 with the same energy per nucleon, require less laser power to be accelerated to the required energy for the hadron therapy.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). Accelerator & Fusion Research Division

Sponsoring Organization:: USDOE Office of Science (SC)

Grant/Contract Number:: AC02-05CH11231; FG02-12ER41798; AC02- 05CH11231

OSTI ID:: 1188514

Alternate ID(s):: OSTI ID: 1209689; OSTI ID: 1234541

Report Number(s):: LBNL-186519; PRABFM; 061302

Journal Information:: Physical Review Special Topics. Accelerators and Beams, Journal Name: Physical Review Special Topics. Accelerators and Beams Vol. 18 Journal Issue: 6; ISSN 1098-4402

Publisher:: American Physical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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Cited by: 26 works

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