The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as Anticancer Agents

Journal Article · Thu Apr 23 00:00:00 EDT 2015 · J. Med. Chem.

DOI:https://doi.org/10.1021/jm501740a· OSTI ID:1183595

Liu, Yong; Lang, Yunhui; Patel, Narendra Kumar; Ng, Grace; Laufer, Radoslaw; Li, Sze-Wan; Edwards, Louise; Forrest, Bryan; Sampson, Peter B.; Feher, Miklos; Ban, Fuqiang; Awrey, Donald E.; Beletskaya, Irina; Mao, Guodong; Hodgson, Richard; Plotnikova, Olga; Qiu, Wei; Chirgadze, Nickolay Y.; Mason, Jacqueline M.; Wei, Xin ; Lin, Dan Chi-Chia; Che, Yi; Kiarash, Reza; Madeira, Brian; Fletcher, Graham C.; Mak, Tak W.; Bray, Mark R.; Pauls, Henry W. ^[1]

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1. UHN

Abstract not provided

• Research Organization: Advanced Photon Source (APS), Argonne National Laboratory (ANL), Argonne, IL (US)
• Sponsoring Organization: FOREIGN
• OSTI ID: 1183595
• Journal Information: J. Med. Chem., Journal Name: J. Med. Chem. Journal Issue: (8) ; 04, 2015 Vol. 58
• Country of Publication: United States
• Language: ENGLISH