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The tmRNA website

Journal Article · · Nucleic Acids Research
DOI:https://doi.org/10.1093/nar/gku1109· OSTI ID:1183117
 [1];  [1]
  1. Sandia National Lab. (SNL-CA), Livermore, CA (United States)

We report that the transfer-messenger RNA (tmRNA) and its partner protein SmpB act together in resolving problems arising when translating bacterial ribosomes reach the end of mRNA with no stop codon. Their genes have been found in nearly all bacterial genomes and in some organelles. The tmRNA Website serves tmRNA sequences, alignments and feature annotations, and has recently moved to http: //bioinformatics.sandia.gov/tmrna/. New features include software used to find the sequences, an update raising the number of unique tmRNA sequences from 492 to 1716, and a database of SmpB sequences which are served along with the tmRNA sequence from the same organism.

Research Organization:
Sandia National Laboratories (SNL-CA), Livermore, CA (United States)
Sponsoring Organization:
USDOE National Nuclear Security Administration (NNSA)
Grant/Contract Number:
AC04-94AL85000
OSTI ID:
1183117
Report Number(s):
SAND2014--17264J; 537177
Journal Information:
Nucleic Acids Research, Journal Name: Nucleic Acids Research Journal Issue: D1 Vol. 43; ISSN 0305-1048
Publisher:
Oxford University PressCopyright Statement
Country of Publication:
United States
Language:
English

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Cited By (11)

Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA journal September 2018
A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites journal August 2018
Comparing miRNA structure of mirtrons and non-mirtrons journal February 2018
A semi-supervised machine learning framework for microRNA classification journal October 2019
PPI-Detect: A support vector machine model for sequence-based prediction of protein-protein interactions: PPI-Detect: A Support Vector Machine Model for Sequence-Based Prediction of Protein-Protein Interactions journal February 2019
Requirement of transfer-messenger RNA for the growth of Bacillus subtilis under stresses: Physiological role of B. subtilis tmRNA journal August 2000
tmRNAs that encode proteolysis-inducing tags are found in all known bacterial genomes: A two-piece tmRNA functions in Caulobacter journal July 2000
Ribosome pausing, arrest and rescue in bacteria and eukaryotes journal March 2017
Comparing miRNA structure of mirtrons and non-mirtrons journal November 2017
Evaluation of a novel real-time PCR test based on the ssrAgene for the identification of group B streptococci in vaginal swabs journal September 2009
A mutagenesis screen for essential plastid biogenesis genes in human malaria parasites journal February 2019

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