Hydrolysis of DFP and the Nerve Agent ( S )-Sarin by DFPase Proceeds along Two Different Reaction Pathways: Implications for Engineering Bioscavengers

Wymore, Troy; Field, Martin J.; Langan, Paul; Smith, Jeremy C.; Parks, Jerry M.

doi:10.1021/jp410422c

Title: Hydrolysis of DFP and the Nerve Agent ( S )-Sarin by DFPase Proceeds along Two Different Reaction Pathways: Implications for Engineering Bioscavengers

Journal Article · Mon Apr 21 00:00:00 EDT 2014 · Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces and Biophysical Chemistry

DOI:https://doi.org/10.1021/jp410422c· OSTI ID:1177836

Wymore, Troy ^[1]; Field, Martin J. ^[2]; Langan, Paul ^[3]; Smith, Jeremy C. ^[1]; Parks, Jerry M. ^[4]

UT/ORNL Center for Molecular Biophysics, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6309, United States, Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, Tennessee 37996, United States
Institut de Biologie Structurale “Jean-Pierre Ebel”, 41 rue Jules Horowitz, 38027 Grenoble Cedex 1, France
Center for Structural and Molecular Biology, Biology and Soft Matter Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6309, United States
UT/ORNL Center for Molecular Biophysics, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6309, United States

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Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA)

Grant/Contract Number:: AC05-00OR22752

OSTI ID:: 1177836

Journal Information:: Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces and Biophysical Chemistry, Journal Name: Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces and Biophysical Chemistry Vol. 118 Journal Issue: 17; ISSN 1520-6106

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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