Inhibitors of glycogen synthase 3 kinase
Patent
·
OSTI ID:1175761
Compounds of formula 1: ##STR00001## wherein R.sub.1 is alkyl, cycloalkyl, aryl, aralkyl, heteroaryl, or heteroaralkyl, substituted with 0 3 substituents selected from lower alkyl, halo, hydroxy, lower alkoxy, amino, lower alkyl-amino, and nitro; R.sub.2 is hydroxy, amino, or lower alkoxy; R.sub.3 is H, lower alkyl, lower acyl, lower alkoxy-acyl, or amino-acyl; R.sub.4 is H or lower alkyl; and pharmaceutically acceptable salts and esters thereof; are effective inhibitors of GSK3.
- Research Organization:
- 7 Healthy Communities Institute Corporation; 2 Clinical Computer Systems Incorporated; Chiron Corporation; 3 Pdicta Corporation; 8 Trade Technologies Inc.; 9 Insight Catastrophe Solutions, Llc; 6 Webshade Pty Limited; 0 Pokos Communications Corp; 1 Vaucher Aerospace Corporation; 5 Leica Biosystems Melbourne Pty Lt; 4 Terra Imaging
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- AC03-76SF00098
- Assignee:
- 7 Healthy Communities Institute Corporation; 2 Clinical Computer Systems Incorporated; Chiron Corporation; 3 Pdicta Corporation; 8 Trade Technologies Inc.; 9 Insight Catastrophe Solutions, Llc; 6 Webshade Pty Limited; 0 Pokos Communications Corp; 1 Vaucher Aerospace Corporation; 5 Leica Biosystems Melbourne Pty Lt; 4 Terra Imaging
- Patent Number(s):
- 7,053,097
- Application Number:
- 09/707,548
- OSTI ID:
- 1175761
- Country of Publication:
- United States
- Language:
- English
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