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Title: Method of increasing conversion of a fatty acid to its corresponding dicarboxylic acid

Patent ·
OSTI ID:1175031

A nucleic acid sequence including a CYP promoter operably linked to nucleic acid encoding a heterologous protein is provided to increase transcription of the nucleic acid. Expression vectors and host cells containing the nucleic acid sequence are also provided. The methods and compositions described herein are especially useful in the production of polycarboxylic acids by yeast cells.

Research Organization:
Cognis Corporation, Ambler, PA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FC36-95GO10099
Assignee:
Cognis Corporation (Ambler, PA)
Patent Number(s):
6,790,640
Application Number:
10/400,902
OSTI ID:
1175031
Country of Publication:
United States
Language:
English

References (1)

Characterization of a second alkane-inducible cytochrome P450-encoding gene, CYP52A2, from Candida tropicalis journal September 1991