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Title: Planar flow-by electrode capacitive electrospray ion source

Patent ·
OSTI ID:1174682

An electrospray ion source includes a chamber including a channel region therein, the channel including at least one inlet for directing a solution into the channel and at least a first and a second outlet for transmitting the solution or derivatives therefrom out from channel. Structure for separating ions in the solution is provided from separating the solution into at least a first and a second flow stream portion. The first flow stream portion is enriched in negative ions and the second flow stream portion is enriched in positive ions. The first flow stream portion is adapted to exit the chamber through the first outlet while the second flow stream portion is adapted to exit the chamber through the second outlet. A method of charge separation can include the step of simultaneously providing at least two gas phase ion stream portions having opposite polarity.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-00OR22725
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
Patent Number(s):
6,677,593
Application Number:
10/229,657
OSTI ID:
1174682
Country of Publication:
United States
Language:
English

References (8)

Peer Reviewed: Split-Flow Thin Fractionation. journal April 2000
Isoelectric Split-Flow Thin (SPLITT) Fractionation of Proteins journal December 1997
A brief overview of the present status of the mechanisms involved in electrospray mass spectrometry journal January 2000
Polymer Microspray with an Integrated Thick-Film Microelectrode journal November 2001
Development of Electrical Field-Flow Fractionation journal April 2000
A System Based on Split-Flow Lateral-Transport Thin (SPLITT) Separation Cells for Rapid and Continuous Particle Fractionation journal November 1985
Effect of multiple sprayers on dynamic range and flow rate limitations in electrospray and ionspray mass spectrometry journal July 1994
Hydrodynamic Characterization of SPLITT Fractionation Cells journal December 1995

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