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Formulations for neutralization of chemical and biological toxants

Patent ·
OSTI ID:1174337
;

A formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents. The formulation of the present invention non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The at least one reactive compound can be an oxidizing compound, a nucleophilic compound or a mixture of both. The formulation can kill up to 99.99999% of bacterial spores within one hour of exposure.

Research Organization:
Sandia National Laboratories (SNL-CA), Livermore, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Number(s):
6,566,574
Application Number:
09/607,586
OSTI ID:
1174337
Country of Publication:
United States
Language:
English

References (8)

Toward a broad spectrum decontaminant for reactive toxic phosphates/phosphonates: N-alkyl-3-iodosopyridinium-4-carboxylates journal September 1993
Structure and Composition of Resistant Layers in Bacterial Spore Coats journal March 1970
Peroxyhydrolysis of nerve agent VX and model compounds and related nucleophilic reactions journal January 1997
Synthesis of hybrid inorganic–organic mesoporous silica by co-condensation of siloxane and organosiloxane precursors journal January 1996
Bacterial spores and chemical sporicidal agents. journal April 1990
Efficient catalytic cleavage of reactive phosphates by a functionalized o-iodosobenzoate surfactant journal February 1986
Comparative sporicidal effects of liquid chemical agents. journal January 1996
Lysis of Bacterial Spores with Hydrogen Peroxide journal December 1969

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Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
59 BASIC BIOLOGICAL SCIENCES