Embodiments of microfluidic hubs and systems are described that may be used to connect fluidic modules. A space between surfaces may be set by fixtures described herein. In some examples a fixture may set substrate-to-substrate spacing based on a distance between registration surfaces on which the respective substrates rest. Fluidic interfaces are described, including examples where fluid conduits (e.g. capillaries) extend into the fixture to the space between surfaces. Droplets of fluid may be introduced to and/or removed from microfluidic hubs described herein, and fluid actuators may be used to move droplets within the space between surfaces. Continuous flow modules may be integrated with the hubs in some examples.
Bartsch, Michael S, et al. "Microfluidic hubs, systems, and methods for interface fluidic modules." US 8,940,147, United States Patent and Trademark Office, Jan. 2015.
Bartsch, Michael S, Claudnic, Mark R, Kim, Hanyoup, Patel, Kamlesh D, Renzi, Ronald F, & Van De Vreugde, James L (2015). Microfluidic hubs, systems, and methods for interface fluidic modules (U.S. Patent No.
Bartsch, Michael S, Claudnic, Mark R, Kim, Hanyoup, et al., "Microfluidic hubs, systems, and methods for interface fluidic modules," US 8,940,147, issued January 27, 2015.
@misc{osti_1168691,
author = {Bartsch, Michael S and Claudnic, Mark R and Kim, Hanyoup and Patel, Kamlesh D and Renzi, Ronald F and Van De Vreugde, James L},
title = {Microfluidic hubs, systems, and methods for interface fluidic modules},
annote = {Embodiments of microfluidic hubs and systems are described that may be used to connect fluidic modules. A space between surfaces may be set by fixtures described herein. In some examples a fixture may set substrate-to-substrate spacing based on a distance between registration surfaces on which the respective substrates rest. Fluidic interfaces are described, including examples where fluid conduits (e.g. capillaries) extend into the fixture to the space between surfaces. Droplets of fluid may be introduced to and/or removed from microfluidic hubs described herein, and fluid actuators may be used to move droplets within the space between surfaces. Continuous flow modules may be integrated with the hubs in some examples.},
url = {https://www.osti.gov/biblio/1168691},
place = {United States},
year = {2015},
month = {01},
note = {US Patent
IEEE Sixteenth Annual International Conference on Micro Electro Mechanical Systems, The Sixteenth Annual International Conference on Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto. IEEEhttps://doi.org/10.1109/MEMSYS.2003.1189752