Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum

Li, Xiaochun; Roberti, Rita; Blobel, Günter

doi:10.1038/nature13797

Title: Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum

Journal Article · Wed Mar 21 00:00:00 EDT 2018 · Nature

DOI:https://doi.org/10.1038/nature13797· OSTI ID:1168528

Li, Xiaochun; Roberti, Rita; Blobel, Günter ^[1]

Perugia

Cite

Export

Save

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: UNIVERSITYHHMI

OSTI ID:: 1168528

Journal Information:: Nature, Vol. 517, Issue 01, 2015

Country of Publication:: United States

Language:: ENGLISH

References (30)

A global topology map of the Saccharomyces cerevisiae membrane proteome Kim, H.; Melen, K.; Osterberg, M. Proceedings of the National Academy of Sciences, Vol. 103, Issue 30 https://doi.org/10.1073/pnas.0604075103	journal	July 2006
Malformation syndromes caused by disorders of cholesterol synthesis Porter, Forbes D.; Herman, Gail E. Journal of Lipid Research, Vol. 52, Issue 1 https://doi.org/10.1194/jlr.R009548	journal	October 2010
Primary characterization of dominant cell surface proteins of halotolerant methanotroph Methylomicrobium alcaliphilum 20Z Shchukin, V. N.; Khmelenina, V. N.; Eshinimayev, B. Ts. Microbiology, Vol. 80, Issue 5 https://doi.org/10.1134/S0026261711050122	journal	October 2011
A lamin B receptor in the nuclear envelope. Worman, H. J.; Yuan, J.; Blobel, G. Proceedings of the National Academy of Sciences, Vol. 85, Issue 22 https://doi.org/10.1073/pnas.85.22.8531	journal	November 1988
Sterol dependent regulation of human TM7SF2 gene expression: Role of the encoded 3β-hydroxysterol Δ14-reductase in human cholesterol biosynthesis Bennati, Anna Maria; Castelli, Marilena; Della Fazia, Maria Agnese Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Vol. 1761, Issue 7 https://doi.org/10.1016/j.bbalip.2006.05.004	journal	July 2006
Steroid hormone synthesis in mitochondria Miller, Walter L. Molecular and Cellular Endocrinology, Vol. 379, Issue 1-2 https://doi.org/10.1016/j.mce.2013.04.014	journal	October 2013
Substructure solution with SHELXD Schneider, Thomas R.; Sheldrick, George M. Acta Crystallographica Section D Biological Crystallography, Vol. 58, Issue 10 https://doi.org/10.1107/S0907444902011678	journal	September 2002
A comprehensive classification system for lipids Fahy, Eoin; Subramaniam, Shankar; Brown, H. Alex Journal of Lipid Research, Vol. 46, Issue 5 https://doi.org/10.1194/jlr.E400004-JLR200	journal	February 2005
Smith–Lemli–Opitz syndrome: pathogenesis, diagnosis and management Porter, Forbes D. European Journal of Human Genetics, Vol. 16, Issue 5 https://doi.org/10.1038/ejhg.2008.10	journal	February 2008
Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues vonHeijne, Gunnar Nature, Vol. 341, Issue 6241 https://doi.org/10.1038/341456a0	journal	October 1989
Dali server: conservation mapping in 3D Holm, Liisa; Rosenstrï¿½m, Pï¿½ivi Nucleic Acids Research, Vol. 38, Issue suppl_2 https://doi.org/10.1093/nar/gkq366	journal	May 2010
MolProbity : all-atom structure validation for macromolecular crystallography Chen, Vincent B.; Arendall, W. Bryan; Headd, Jeffrey J. Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1 https://doi.org/10.1107/S0907444909042073	journal	December 2009
Coot model-building tools for molecular graphics Emsley, Paul; Cowtan, Kevin Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 12, p. 2126-2132 https://doi.org/10.1107/S0907444904019158	journal	November 2004
Early steps in steroidogenesis: intracellular cholesterol trafficking: Thematic Review Series: Genetics of Human Lipid Diseases Miller, Walter L.; Bose, Himangshu S. Journal of Lipid Research, Vol. 52, Issue 12 https://doi.org/10.1194/jlr.R016675	journal	October 2011
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice Thompson, Julie D.; Higgins, Desmond G.; Gibson, Toby J. Nucleic Acids Research, Vol. 22, Issue 22, p. 4673-4680 https://doi.org/10.1093/nar/22.22.4673	journal	January 1994
Autosomal Recessive HEM/Greenberg Skeletal Dysplasia Is Caused by 3β-Hydroxysterol Δ14-Reductase Deficiency Due to Mutations in the Lamin B Receptor Gene Waterham, Hans R.; Koster, Janet; Mooyer, Petra The American Journal of Human Genetics, Vol. 72, Issue 4 https://doi.org/10.1086/373938	journal	April 2003
Disorders of sterol synthesis: Beyond Smith-Lemli-Opitz syndrome Herman, Gail E.; Kratz, Lisa American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Vol. 160C, Issue 4 https://doi.org/10.1002/ajmg.c.31340	journal	October 2012
Lamin B receptor: Multi-tasking at the nuclear envelope Olins, Ada L.; Rhodes, Gale; Welch, David B. Mark Nucleus, Vol. 1, Issue 1 https://doi.org/10.4161/nucl.1.1.10515	journal	January 2010
PHENIX: a comprehensive Python-based system for macromolecular structure solution Adams, Paul D.; Afonine, Pavel V.; Bunkóczi, Gábor Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2, p. 213-221 https://doi.org/10.1107/S0907444909052925	journal	January 2010
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders Miller, Walter L.; Auchus, Richard J. Endocrine Reviews, Vol. 32, Issue 1 https://doi.org/10.1210/er.2010-0013	journal	February 2011
Human lamin B receptor exhibits sterol C14-reductase activity in Saccharomyces cerevisiae Silve, Sandra; Dupuy, Pascal-Henry; Ferrara, Pascual Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 1392, Issue 2-3 https://doi.org/10.1016/S0005-2760(98)00041-1	journal	June 1998
Disruption of the gene encoding 3β-hydroxysterol Δ14-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis: Tm7sf2 knockout mice Bennati, Anna M.; Schiavoni, Gianluca; Franken, Sebastian FEBS Journal, Vol. 275, Issue 20 https://doi.org/10.1111/j.1742-4658.2008.06637.x	journal	September 2008
Protein Sensors for Membrane Sterols Goldstein, Joseph L.; DeBose-Boyd, Russell A.; Brown, Michael S. Cell, Vol. 124, Issue 1 https://doi.org/10.1016/j.cell.2005.12.022	journal	January 2006
Mutations causing Greenberg dysplasia but not Pelger anomaly uncouple enzymatic from structural functions of a nuclear membrane protein Clayton, Peter; Fischer, Björn; Mann, Anuska Nucleus, Vol. 1, Issue 4 https://doi.org/10.4161/nucl.1.4.12435	journal	July 2010
Mechanism of Isoprenylcysteine Carboxyl Methylation from the Crystal Structure of the Integral Membrane Methyltransferase ICMT Yang, Jing; Kulkarni, Kiran; Manolaridis, Ioannis Molecular Cell, Vol. 44, Issue 6 https://doi.org/10.1016/j.molcel.2011.10.020	journal	December 2011
Crystal Structure of Human Liver Δ ⁴ -3-Ketosteroid 5β-Reductase (AKR1D1) and Implications for Substrate Binding and Catalysis Di Costanzo, Luigi; Drury, Jason E.; Penning, Trevor M. Journal of Biological Chemistry, Vol. 283, Issue 24 https://doi.org/10.1074/jbc.M801778200	journal	April 2008
[20] Processing of X-ray diffraction data collected in oscillation mode Otwinowski, Zbyszek; Minor, Wladek Macromolecular Crystallography Part A, 307-326 https://doi.org/10.1016/S0076-6879(97)76066-X	book	January 1997
Cloning and expression of sterol Δ14-reductase from bovine liver: Bovine sterol Δ14-reductase cloning Roberti, Rita; Bennati, Anna Maria; Galli, Giovanni European Journal of Biochemistry, Vol. 269, Issue 1 https://doi.org/10.1046/j.0014-2956.2001.02646.x	journal	January 2002
Automated MAD and MIR structure solution Terwilliger, Thomas C.; Berendzen, Joel Acta Crystallographica Section D Biological Crystallography, Vol. 55, Issue 4 https://doi.org/10.1107/S0907444999000839	journal	April 1999
Phaser crystallographic software McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D. Journal of Applied Crystallography, Vol. 40, Issue 4 https://doi.org/10.1107/S0021889807021206	journal	July 2007

Similar Records

Structure of an Integral Membrane Sterol Reductase from Methylomicrobium Alcaliphilum

Journal Article · Thu Jan 01 00:00:00 EST 2015 · Nature (London) · OSTI ID:1168528

Li, X; Roberti, R; Blobel, G

Rare Earth Elements Alter Redox Balance in Methylomicrobium alcaliphilum 20Z^R

Journal Article · Tue Nov 27 00:00:00 EST 2018 · Frontiers in Microbiology · OSTI ID:1168528

Akberdin, Ilya R.; Collins, David A.; Hamilton, Richard; +6 more

Author Correction: Methane utilization in Methylomicrobium alcaliphilum 20ZR: a systems approach

Journal Article · Wed Mar 14 00:00:00 EDT 2018 · Scientific Reports · OSTI ID:1168528

Akberdin, Ilya R.; Thompson, Merlin; Hamilton, Richard; +5 more

Title: Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum

Citation Formats

References (30)

Similar Records

Related Subjects