High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875
- Takeda Cali
- Research Organization:
- Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
- Sponsoring Organization:
- NCINIGMS
- OSTI ID:
- 1162336
- Journal Information:
- Nature, Vol. 513, Issue 09, 2014
- Country of Publication:
- United States
- Language:
- ENGLISH
Similar Records
Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40
Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures
Crystal structures of agonist-bound human cannabinoid receptor CB1
Journal Article
·
Mon Jun 05 00:00:00 EDT 2017
· Nature Structural & Molecular Biology
·
OSTI ID:1162336
+31 more
Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1S,2S,5R,6S-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures
Journal Article
·
Thu Feb 26 00:00:00 EST 2015
· J. Med. Chem.
·
OSTI ID:1162336
+36 more
Crystal structures of agonist-bound human cannabinoid receptor CB1
Journal Article
·
Wed Jul 05 00:00:00 EDT 2017
· Nature (London)
·
OSTI ID:1162336
+17 more