X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination

Khvostichenko, Daria S.; Schieferstein, Jeremy M.; Pawate, Ashtamurthy S.; Laible, Philip D.; Kenis, Paul J. A.

doi:10.1021/cg5011488

X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination

Journal Article · Wed Sep 10 00:00:00 EDT 2014 · Crystal Growth and Design

DOI:https://doi.org/10.1021/cg5011488· OSTI ID:1158727

Khvostichenko, Daria S. ^[1]; Schieferstein, Jeremy M. ^[1]; Pawate, Ashtamurthy S. ^[1]; Laible, Philip D. ^[2]; Kenis, Paul J. A. ^[1]

Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana−Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States
Biosciences Division, Argonne National Laboratory, Argonne, Illinois 60439, United States

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States)

Sponsoring Organization:: USDOE Advanced Research Projects Agency - Energy (ARPA-E)

Grant/Contract Number:: AC02-06CH11357

OSTI ID:: 1158727

Alternate ID(s):: OSTI ID: 1225366
OSTI ID: 1393969

Journal Information:: Crystal Growth and Design, Journal Name: Crystal Growth and Design Journal Issue: 10 Vol. 14; ISSN 1528-7483

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: France

Language:: English

References (42)

Recent Progress in the Structure Determination of GPCRs, a Membrane Protein Family with High Potential as Pharmaceutical Targets Cherezov, Vadim; Abola, Enrique; Stevens, Raymond C. Methods in Molecular Biology https://doi.org/10.1007/978-1-60761-762-4_8	book	January 2010
A plug-based microfluidic system for dispensing lipidic cubic phase (LCP) material validated by crystallizing membrane proteins in lipidic mesophases Li, Liang; Fu, Qiang; Kors, Christopher A. Microfluidics and Nanofluidics, Vol. 8, Issue 6 https://doi.org/10.1007/s10404-009-0512-8	journal	October 2009
Behavior of capillary valves in centrifugal microfluidic devices prepared by three-dimensional printing Moore, Jessica L.; McCuiston, Austin; Mittendorf, Isaac Microfluidics and Nanofluidics, Vol. 10, Issue 4 https://doi.org/10.1007/s10404-010-0721-1	journal	November 2010
Lipidic Cubic Phase Crystal Structure of the Photosynthetic Reaction Centre from Rhodobacter sphaeroides at 2.35Å Resolution Katona, Gergely; Andréasson, Ulf; Landau, Ehud M. Journal of Molecular Biology, Vol. 331, Issue 3 https://doi.org/10.1016/S0022-2836(03)00751-4	journal	August 2003
Chapter 4 Monoacylglycerols Caffrey, M.; Lyons, J.; Smyth, T. Current Topics in Membranes https://doi.org/10.1016/S1063-5823(09)63004-0	book	January 2009
Microfluidics for drug discovery and development: From target selection to product lifecycle management Kang, L. Drug Discovery Today, Vol. 13, Issue 1-2 https://doi.org/10.1016/j.drudis.2007.10.003	journal	January 2008
Room to Move: Crystallizing Membrane Proteins in Swollen Lipidic Mesophases Cherezov, Vadim; Clogston, Jeffrey; Papiz, Miroslav Z. Journal of Molecular Biology, Vol. 357, Issue 5 https://doi.org/10.1016/j.jmb.2006.01.049	journal	April 2006
Lipidic Sponge Phase Crystallization of Membrane Proteins Wadsten, Pia; Wöhri, Annemarie B.; Snijder, Arjan Journal of Molecular Biology, Vol. 364, Issue 1 https://doi.org/10.1016/j.jmb.2006.06.043	journal	November 2006
Integrated microfluidic reactors Lin, Wei-Yu; Wang, Yanju; Wang, Shutao Nano Today, Vol. 4, Issue 6 https://doi.org/10.1016/j.nantod.2009.10.007	journal	December 2009
Lipidic cubic phase technologies for membrane protein structural studies Cherezov, Vadim Current Opinion in Structural Biology, Vol. 21, Issue 4 https://doi.org/10.1016/j.sbi.2011.06.007	journal	August 2011
Two-layer multiplexed peristaltic pumps for high-density integrated microfluidics Cole, Matthew C.; Desai, Amit V.; Kenis, Paul J. A. Sensors and Actuators B: Chemical, Vol. 151, Issue 2, p. 384-393 https://doi.org/10.1016/j.snb.2010.07.012	journal	January 2011
Fabrication of X-ray compatible microfluidic platforms for protein crystallization Guha, Sudipto; Perry, Sarah L.; Pawate, Ashtamurthy S. Sensors and Actuators B: Chemical, Vol. 174 https://doi.org/10.1016/j.snb.2012.08.048	journal	November 2012
From 3D cell culture to organs-on-chips Huh, Dongeun; Hamilton, Geraldine A.; Ingber, Donald E. Trends in Cell Biology, Vol. 21, Issue 12 https://doi.org/10.1016/j.tcb.2011.09.005	journal	December 2011
Diversity and modularity of G protein-coupled receptor structures Katritch, Vsevolod; Cherezov, Vadim; Stevens, Raymond C. Trends in Pharmacological Sciences, Vol. 33, Issue 1 https://doi.org/10.1016/j.tips.2011.09.003	journal	January 2012
Nonlinear Optical Imaging of Integral Membrane Protein Crystals in Lipidic Mesophases Kissick, David J.; Gualtieri, Ellen J.; Simpson, Garth J. Analytical Chemistry, Vol. 82, Issue 2 https://doi.org/10.1021/ac902139w	journal	January 2010
ChipX: A Novel Microfluidic Chip for Counter-Diffusion Crystallization of Biomolecules and in Situ Crystal Analysis at Room Temperature Pinker, Franziska; Brun, Mathieu; Morin, Pierre Crystal Growth & Design, Vol. 13, Issue 8 https://doi.org/10.1021/cg301757g	journal	July 2013
From Macrofluidics to Microfluidics for the Crystallization of Biological Macromolecules ^† Sauter, Claude; Dhouib, Kaouthar; Lorber, Bernard Crystal Growth & Design, Vol. 7, Issue 11 https://doi.org/10.1021/cg700955f	journal	November 2007
Shear Rheology of Lyotropic Liquid Crystals: A Case Study Mezzenga, Raffaele; Meyer, Cedric; Servais, Colin Langmuir, Vol. 21, Issue 8 https://doi.org/10.1021/la046964b	journal	April 2005
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography Weierstall, Uwe; James, Daniel; Wang, Chong Nature Communications, Vol. 5, Issue 1 https://doi.org/10.1038/ncomms4309	journal	February 2014
Crystallizing membrane proteins using lipidic mesophases Caffrey, Martin; Cherezov, Vadim Nature Protocols, Vol. 4, Issue 5 https://doi.org/10.1038/nprot.2009.31	journal	April 2009
How many drug targets are there? Overington, John P.; Al-Lazikani, Bissan; Hopkins, Andrew L. Nature Reviews Drug Discovery, Vol. 5, Issue 12 https://doi.org/10.1038/nrd2199	journal	December 2006
A microfluidic processor for gene expression profiling of single human embryonic stem cells Zhong, Jiang F.; Chen, Yan; Marcus, Joshua S. Lab Chip, Vol. 8, Issue 1 https://doi.org/10.1039/B712116D	journal	January 2008
Toward on-chip X-ray analysis Greaves, Eduardo D.; Manz, Andreas Lab on a Chip, Vol. 5, Issue 4 https://doi.org/10.1039/b415836a	journal	January 2005
X-ray microfocussing combined with microfluidics for on-chip X-ray scattering measurements Barrett, Ray; Faucon, Marc; Lopez, John Lab on a Chip, Vol. 6, Issue 4 https://doi.org/10.1039/b517055a	journal	January 2006
Microfluidic chips for the crystallization of biomacromolecules by counter-diffusion and on-chip crystal X-ray analysis Dhouib, Kaouthar; Khan Malek, Chantal; Pfleging, Wilhelm Lab on a Chip, Vol. 9, Issue 10 https://doi.org/10.1039/b819362b	journal	January 2009
A microfluidic approach for protein structure determination at room temperature via on-chip anomalous diffraction Perry, Sarah L.; Guha, Sudipto; Pawate, Ashtamurthy S. Lab on a Chip, Vol. 13, Issue 16 https://doi.org/10.1039/c3lc50276g	journal	January 2013
From The Cover: Systematic investigation of protein phase behavior with a microfluidic formulator Hansen, C. L.; Sommer, M. O. A.; Quake, S. R. Proceedings of the National Academy of Sciences, Vol. 101, Issue 40, p. 14431-14436 https://doi.org/10.1073/pnas.0405847101	journal	September 2004
Accessing protein conformational ensembles using room-temperature X-ray crystallography Fraser, J. S.; van den Bedem, H.; Samelson, A. J. Proceedings of the National Academy of Sciences, Vol. 108, Issue 39 https://doi.org/10.1073/pnas.1111325108	journal	September 2011
How root-mean-square distance (r.m.s.d.) values depend on the resolution of protein structures that are compared Carugo, Oliviero Journal of Applied Crystallography, Vol. 36, Issue 1 https://doi.org/10.1107/S0021889802020502	journal	January 2003
A robotic system for crystallizing membrane and soluble proteins in lipidic mesophases Cherezov, Vadim; Peddi, Avinash; Muthusubramaniam, Lalitha Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 10 https://doi.org/10.1107/S0907444904019109	journal	September 2004
Pros and cons of cryocrystallography: should we also collect a room-temperature data set? Dunlop, Kirsty V.; Irvin, Randall T.; Hazes, Bart Acta Crystallographica Section D Biological Crystallography, Vol. 61, Issue 1 https://doi.org/10.1107/S0907444904027179	journal	December 2004
In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels Ng, Joseph D.; Clark, Peter J.; Stevens, Raymond C. Acta Crystallographica Section D Biological Crystallography, Vol. 64, Issue 2 https://doi.org/10.1107/S0907444907060064	journal	January 2008
The plug-based nanovolume Microcapillary Protein Crystallization System (MPCS) Gerdts, Cory J.; Elliott, Mark; Lovell, Scott Acta Crystallographica Section D Biological Crystallography, Vol. 64, Issue 11 https://doi.org/10.1107/S0907444908028060	journal	October 2008
Radiation damage in macromolecular crystallography: what is it and why should we care? Garman, Elspeth F. Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4 https://doi.org/10.1107/S0907444910008656	journal	March 2010
X-CHIP: an integrated platform for high-throughput protein crystallization and on-the-chip X-ray diffraction data collection Kisselman, Gera; Qiu, Wei; Romanov, Vladimir Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 6 https://doi.org/10.1107/S0907444911011589	journal	May 2011
Laue Crystallography for Studying Rapid Reactions Ren, Z.; Moffat, K. Journal of Synchrotron Radiation, Vol. 1, Issue 1 https://doi.org/10.1107/S0909049594006692	journal	October 1994
From screen to structure with a harvestable microfluidic device Stojanoff, Vivian; Jakoncic, Jean; Oren, Deena A. Acta Crystallographica Section F Structural Biology and Crystallization Communications, Vol. 67, Issue 8 https://doi.org/10.1107/S1744309111024456	journal	July 2011
Miniaturized and highly parallel protein crystallization on a microfluidic disc Steinert, C. P.; Mueller-Dieckmann, J.; Weiss, M. 2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS) https://doi.org/10.1109/MEMSYS.2007.4433159	conference	January 2007
Chaotic Mixer for Microchannels Stroock, A. D. Science, Vol. 295, Issue 5555 https://doi.org/10.1126/science.1066238	journal	January 2002
Serial Femtosecond Crystallography of G Protein-Coupled Receptors Liu, W.; Wacker, D.; Gati, C. Science, Vol. 342, Issue 6165 https://doi.org/10.1126/science.1244142	journal	December 2013
Monoolein Lipid Phases as Incorporation and Enrichment Materials for Membrane Protein Crystallization Wallace, Ellen; Dranow, David; Laible, Philip D. PLoS ONE, Vol. 6, Issue 8 https://doi.org/10.1371/journal.pone.0024488	journal	August 2011
Controlled In Meso Phase Crystallization – A Method for the Structural Investigation of Membrane Proteins Kubicek, Jan; Schlesinger, Ramona; Baeken, Christian PLoS ONE, Vol. 7, Issue 4 https://doi.org/10.1371/journal.pone.0035458	journal	April 2012

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X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination

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X-ray Transparent Microfluidic Chip for Mesophase-Based Crystallization of Membrane Proteins and On-Chip Structure Determination

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