Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma cruzi Sterol 14α-Demethylase: Two Regions of the Enzyme Molecule Potentiate Its Inhibition
Journal Article
·
· Journal of Medicinal Chemistry
- Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232, United States
- Department of Microbiology and Immunology, Meharry Medical College, Nashville, Tennessee 37208, United States
- Synchrotron Research Center, Life Science Collaborative Access Team, Northwestern University, Argonne, Illinois 60439, United States
- “Istituto Pasteur-Fondazione Cenci Bolognetti”, Department of “Chimica e Tecnologie del Farmaco”, Sapienza University of Rome, Rome, 00185, Italy
- Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232, United States, Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232, United States
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 1158716
- Journal Information:
- Journal of Medicinal Chemistry, Journal Name: Journal of Medicinal Chemistry Vol. 57 Journal Issue: 15; ISSN 0022-2623
- Publisher:
- American Chemical SocietyCopyright Statement
- Country of Publication:
- United States
- Language:
- English
Cited by: 32 works
Citation information provided by
Web of Science
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