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Title: Radio-methyl vorozole and methods for making and using the same

Abstract

Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.

Inventors:
; ;
Publication Date:
Research Org.:
BNL (Brookhaven National Laboratory (BNL), Upton, NY (United States))
Sponsoring Org.:
USDOE
OSTI Identifier:
1150092
Patent Number(s):
8,802,053
Application Number:
13/847,136
Assignee:
Brookhaven Science Associates, LLC (Upton, NY) BNL
DOE Contract Number:
AC02-98CH10886
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Kim, Sung Won, Biegon, Anat, and Fowler, Joanna S. Radio-methyl vorozole and methods for making and using the same. United States: N. p., 2014. Web.
Kim, Sung Won, Biegon, Anat, & Fowler, Joanna S. Radio-methyl vorozole and methods for making and using the same. United States.
Kim, Sung Won, Biegon, Anat, and Fowler, Joanna S. Tue . "Radio-methyl vorozole and methods for making and using the same". United States. doi:. https://www.osti.gov/servlets/purl/1150092.
@article{osti_1150092,
title = {Radio-methyl vorozole and methods for making and using the same},
author = {Kim, Sung Won and Biegon, Anat and Fowler, Joanna S.},
abstractNote = {Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 12 00:00:00 EDT 2014},
month = {Tue Aug 12 00:00:00 EDT 2014}
}

Patent:

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