Water-soluble carbon nanotube compositions for drug delivery and medicinal applications

Tour, James M.; Lucente-Schultz, Rebecca; Leonard, Ashley; Kosynkin, Dmitry V.; Price, Brandi Katherine; Hudson, Jared L.; Conyers, Jr., Jodie L.; Moore, Valerie C.; Casscells, S. Ward; Myers, Jeffrey N.; Milas, Zvonimir L.; Mason, Kathy A.; Milas, Luka

Water-soluble carbon nanotube compositions for drug delivery and medicinal applications

Patent · Tue Jul 22 04:00:00 EDT 2014

OSTI ID:1149690

Tour, James M.; Lucente-Schultz, Rebecca; Leonard, Ashley; Kosynkin, Dmitry V.; Price, Brandi Katherine; Hudson, Jared L.; Conyers, Jr., Jodie L.; Moore, Valerie C.; Casscells, S. Ward; Myers, Jeffrey N.; Milas, Zvonimir L.; Mason, Kathy A.; Milas, Luka

Compositions comprising a plurality of functionalized carbon nanotubes and at least one type of payload molecule are provided herein. The compositions are soluble in water and PBS in some embodiments. In certain embodiments, the payload molecules are insoluble in water. Methods are described for making the compositions and administering the compositions. An extended release formulation for paclitaxel utilizing functionalized carbon nanotubes is also described.

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Research Organization:: William Marsh Rice University, Houston, TX (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-05GO15073

Assignee:: William Marsh Rice University (Houston, TX); Board of Regents, The University of Texas System (Austin, TX)

Patent Number(s):: 8,784,866

Application Number:: 12/245,438

OSTI ID:: 1149690

Country of Publication:: United States

Language:: English

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