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Title: Pantothenic acid biosynthesis in zymomonas

Abstract

Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.

Inventors:
; ;
Publication Date:
Research Org.:
E I du Pont de Nemours and Company, Wilmington, DE (USA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1136700
Patent Number(s):
8,765,426
Application Number:
13/433,343
Assignee:
E I du Pont de Nemours and Company (Wilmington, DE)
DOE Contract Number:  
FC36-07GO17056
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas. United States: N. p., 2014. Web.
Tao, Luan, Tomb, Jean-Francois, & Viitanen, Paul V. Pantothenic acid biosynthesis in zymomonas. United States.
Tao, Luan, Tomb, Jean-Francois, and Viitanen, Paul V. Tue . "Pantothenic acid biosynthesis in zymomonas". United States. https://www.osti.gov/servlets/purl/1136700.
@article{osti_1136700,
title = {Pantothenic acid biosynthesis in zymomonas},
author = {Tao, Luan and Tomb, Jean-Francois and Viitanen, Paul V.},
abstractNote = {Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {7}
}

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Works referenced in this record:

Pentose metabolism in Zymomonas mobilis wild-type and recombinant strains
journal, December 1992

  • Feldmann, SigrunD.; Sahm, Hermann; Sprenger, GeorgA.
  • Applied Microbiology and Biotechnology, Vol. 38, Issue 3
  • DOI: 10.1007/BF00170086

KEGG: Kyoto Encyclopedia of Genes and Genomes
journal, January 2000

  • Kanehisa, Minoru; Goto, Susumu
  • Nucleic Acids Research, Vol. 28, Issue 1, p. 27-30
  • DOI: 10.1093/nar/28.1.27

The KEGG databases at GenomeNet
journal, January 2002


An improved synthetic medium for continuous cultivation of Zymomonas mobilis
journal, April 1984

  • Nipkow, A.; Beyeler, W.; Fiechter, A.
  • Applied Microbiology and Biotechnology, Vol. 19, Issue 4
  • DOI: 10.1007/BF00251843

Escherichia coli l-aspartate-╬▒-decarboxylase: preprotein processing and observation of reaction intermediates by electrospray mass spectrometry
journal, May 1997

  • Ramjee, Manoj K.; Genschel, Ulrich; Abell, Chris
  • Biochemical Journal, Vol. 323, Issue 3
  • DOI: 10.1042/bj3230661

The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4
journal, December 2004

  • Seo, Jeong-Sun; Chong, Hyonyong; Park, Hyun Seok
  • Nature Biotechnology, Vol. 23, Issue 1
  • DOI: 10.1038/nbt1045

Metabolic Engineering of a Pentose Metabolism Pathway in Ethanologenic Zymomonas mobilis
journal, January 1995